Mesotherapy in Czechia

PRP (platelet-rich plasma) therapy at ISCARE's dermatology department uses the patient's own blood, centrifuged to concentrate growth factors, which are then micro-injected into the face or scalp to stimulate collagen production and tissue regeneration. At 5,500 Kč per session and administered by dermatologists, ISCARE's PRP service uses a clinical-grade centrifuge to produce a consistent, high-quality plasma fraction, and targets skin texture, fine lines, and hair thinning.

Platelet-rich plasma (PRP) therapy at EsteticUsti uses the patient's own blood as the source material for a regenerative facial treatment. A small blood sample is centrifuged to concentrate the platelets — the cells whose primary function is wound healing and tissue repair — into a plasma solution 3–5 times richer in growth factors than normal blood. This concentrated PRP is then injected into the dermis of the face, neck, décolletage, hands, or scalp. The growth factors (PDGF, TGF-β, VEGF, IGF-1) activate resident fibroblasts and stem cells, driving collagen production, angiogenesis, and tissue regeneration from within. Because PRP is derived from the patient's own blood, the risk of allergic reaction is negligible.

Skinboosters are injectable skin hydration treatments that place hyaluronic acid or next-generation bioactive serums directly into the dermis using a vital injector device, delivering deep moisture that topical creams cannot reach. Neo Beauty Clinic offers six skinbooster formulations ranging from classic HA hydration to the EXOCEAN vegan exosome formula and the ALLSTEM stem-cell serum, so the physician can match the product to your specific skin needs. Sessions take around thirty minutes including the anaesthetic preparation, and the optimal protocol is two treatments four weeks apart. Treated areas include the face, neck, décolletage and hands.

Profhilo bioremodeling injection — high-concentration HA that hydrates deeply and stimulates collagen and elastin across four skin layers from just five injection points, improving skin quality without adding volume.

Xela Rederm is a Swiss-developed injectable skin booster combining hyaluronic acid with amber acid (sodium succinate) — a Krebs cycle metabolite that stimulates fibroblasts to produce collagen and elastin independent of any external laser or RF energy. The injected formula simultaneously provides deep hydration (from the HA component) and active cellular regeneration (from the succinate component), producing visibly smoother, firmer and more radiant skin within three days. Artmedica Clinic Prague was the first clinic in the Czech Republic to offer Xela Rederm, positioning it as an early adopter of this Swiss aesthetic innovation.

Skin revitalisation mesotherapy delivering customised cocktails of hyaluronic acid, vitamins, minerals, antioxidants and nucleic acids by microinjection directly into the mesodermal skin layer. At Artmedica Clinic Prague a single-point cannula or a 9-needle injector delivers the formula in a structured pattern across face, neck, eye area, décolletage or hands. The intradermal delivery bypasses the skin barrier entirely, achieving concentrations of active ingredients that topical products cannot reach. Results include improved elasticity, hydration, skin appearance and collagen stimulation with minimal downtime.

Profhilo bioremodeling delivers a unique combination of high and low molecular weight hyaluronic acid via just ten injection points using the BAP (Bio Aesthetic Points) technique. Unlike standard dermal fillers it does not add volume or structure — it stimulates the skin's own production of collagen, elastin and HA for firmer, more elastic and visibly hydrated skin. The two-session protocol (one month apart) produces gradual improvement in skin quality that continues to develop for weeks after the final session. Artmedica Clinic Prague offers both standard Profhilo and the Profhilo Structura variant for deeper tissue remodelling.

Rejuran is a polynucleotide (PN) bio-revitaliser derived from highly purified salmon DNA that acts as a biological skin repair signal rather than simply hydrating or filling the skin. When injected into the mid-dermis, polynucleotides stimulate the skin's own fibroblasts to produce collagen and elastin, promote cell regeneration, improve skin barrier integrity and exert anti-inflammatory effects. At Klinika Kasiopea, MUDr. Bittner delivers Rejuran through microinjections after topical anaesthetic application, targeting fine lines, loss of firmness and skin dehydration on the face, neck, décolletage and around the eyes. A course of three sessions two to four weeks apart is standard.

Mesotherapy at RAJSKA Clinic uses biocompatible injectable blends — Neauvia Organic Hydrodeluxe for facial skin, and scalp-specific formulations and hair polynucleotides for hair loss — to deliver active ingredients directly into the target tissue layer. Neauvia Organic uses high-purity HA from non-animal bacterial fermentation, enriched with hydroxyapatite and glycine for enhanced biocompatibility. Scalp mesotherapy and hair polynucleotides address androgenic alopecia, telogen effluvium, and stress-related hair loss with a nutrient-rich injection protocol that extends the anagen (growth) phase of the hair cycle. A course of at least three sessions is standard.

Mesotherapy at Art Ethic delivers a customised cocktail of hyaluronic acid, succinic acid, and vitamins into the skin of the face and décolletage via fine microinjections or microneedling, deeply hydrating and firming the skin at the dermal level. The treatment targets the underlying tissue rather than the skin surface, stimulating natural collagen production and improving elasticity from within. It is well suited to patients in their thirties and forties beginning to notice skin quality changes who want a medically supervised preventive approach, and to those wanting non-surgical skin rejuvenation between or alongside surgical procedures.

Deep skin hydration using injectable skinboosters — lightly cross-linked hyaluronic acid placed into the skin by mesotherapy to improve hydration, elasticity and overall skin quality rather than to add volume. At Ambulance estetické dermatologie MUDr. Mojmír Müller two product lines are offered: Restylane Skinboosters and Neuvia Organic Hydro Deluxe, the latter combining hyaluronic acid with hydroxyapatite and the amino acids glycine and proline. An initial series is recommended, with maintenance roughly every six months.

Skin boosters and biorevitalization deliver hyaluronic acid and revitalising micronutrients into the skin through fine micro-injections to improve hydration, elasticity and glow rather than to add volume. At DermaConcept the menu includes beauty boosters, biorevitalization, Microtox and a BabyGlow protocol, plus a Radiesse option for collagen-stimulating firmness. The treatments suit tired, dull or early-ageing skin and work best as a short course, with results building gradually over the weeks that follow.

An injectable skin-regeneration treatment using polynucleotides — fragments derived from purified DNA — to biostimulate, hydrate and firm the skin. At Estemedic MUDr. Ilona Karasová injects polynucleotides through a series of fine injections to regenerate and rejuvenate tired skin as part of the practice's rejuvenation programme. Rather than filling a wrinkle, they act as a biostimulator, so it is well suited to improving skin quality and resilience; results develop over the weeks after treatment and are usually best as a short course. The full-area treatment starts from 6,000 Kč, with a separate eye-area-only option from 3,500 Kč for the thin, delicate under-eye skin.

Mesotherapy delivers fine micro-injections of hyaluronic acid into the superficial layers of the skin to improve hydration, elasticity and overall quality — rather than adding volume. At Medica Aesthetica dermatologist prim. MUDr. Zdena Stratilová treats the face, neck, décolletage and backs of the hands, areas that show early ageing and dehydration. A course of sessions is usually advised for a visible, cumulative result.

Mesotherapy at BESTÉE Clinic delivers targeted active compounds — hyaluronic acid, collagen, polynucleotides, or a multi-ingredient booster complex — via fine-needle microinjections into the superficial dermis, bypassing the skin barrier to achieve direct tissue-level results. The clinic offers four distinct formulas: a 5ml Booster for dehydrated or fatigued skin, 1ml Hyaluronic Acid for structural restoration and fine-line smoothing, 2ml Collagen for immediate contour improvement lasting 12–18 months, and 1.5ml Nucleofill for cell-level biostimulation with antioxidant and hydration benefits. Treatment is suitable for face, neck, décolletage, and body areas.

Equine collagen injections use 100% type I collagen derived from horses — a high-purity, veterinary-grade alternative to bovine-derived collagen — to replenish the structural collagen matrix that diminishes with age. At AV Aesthetics, fine-needle subcutaneous injections deliver the collagen directly into the dermis of the face, neck, décolletage, or hands, where it may support skin elasticity, firmness, and wrinkle reduction. Emla topical anaesthetic is applied as standard to minimise sensation during injection. Results develop progressively over 2–3 applications spaced roughly 15 days apart, and may last up to 12 months from the final session.

Rejuran is an injectable skin-rejuvenation treatment based on polynucleotides, offered by Modrý pavilon's aesthetics team. It is delivered through fine micro-injections to support skin quality, hydration and texture. Two options are available: Rejuran Healer for general facial skin and Rejuran I, formulated specifically for the delicate under-eye area.

Skin rejuvenation using the patient's own blood plasma (PRP — platelet-rich plasma), which is processed from a small venous blood draw to concentrate growth factors, cytokines and bioactive proteins. At AE Derm this autologous plasma is re-injected into the face or scalp using the VITAL INJECTOR device for precise, uniform delivery. Because PRP is derived from the patient's own blood, rejection or allergic reaction is not a concern. The treatment stimulates collagen synthesis, improves skin quality and is also used for alopecia management.

Profhilo is a highly purified, stabilised hyaluronic acid used for bio-remodelling — it spreads through the skin to deeply hydrate and to stimulate the production of collagen and elastin, improving firmness and quality rather than adding volume. It is delivered through about ten precise micro-injection points (the bio-aesthetic points) on the face, with minimal downtime. At Estéea it is offered as a recommended course of two sessions roughly four weeks apart, and also treats the neck, décolletage and backs of the hands.

Mesotherapy at Esthea Medical delivers a solution of hyaluronic acid, vitamins, amino acids and minerals into the superficial layers of the skin via many micro-injections — either with the precision Vital Injector device or by hand with a fine nano-needle. The hyaluronic acid binds water within the skin, producing deep hydration, firming of lax skin and smoothing of fine lines for a rested, naturally refreshed appearance. The face, neck and décolletage can all be treated. An anaesthetic cream keeps the session comfortable, and a repeat treatment after four weeks is recommended for best results.

Needle Shaping is a micro-invasive treatment that firms the skin and softens fine lines by biostimulation — encouraging the skin and underlying tissue to improve themselves and build volume without injecting any foreign material. At Dermaestet it is offered as a near-painless, gentle alternative for clients who cannot or prefer not to have botulinum toxin or hyaluronic acid, and is also used to help correct some scars and restore volume, most often in the cheeks. Because it relies on the body's own collagen response, results develop over the weeks afterward.

SkinBooster injections at SKIN CARE Liberec deliver cross-linked 20% hyaluronic acid deep into the dermis to achieve long-lasting internal hydration and skin quality improvement that topical products cannot replicate. Unlike standard HA fillers that add structural volume, SkinBooster is a low-viscosity, highly hydrophilic gel designed to integrate into the dermis and attract water molecules over time, progressively improving elasticity, radiance, and fine line texture. The protocol requires two to three sessions spaced approximately one month apart, with effect duration of six to eight months. A numbing cream is applied 30 minutes before each session. Areas include localised zones (eye area, lips, or cheeks) from 6,100 Kč, or larger areas (full face, neck, décolletage) at 12,200 Kč per session, with multi-session packages available.

Hydrolifting is an anti-ageing skin treatment that injects hyaluronic acid together with a cocktail of vitamins and amino acids into the upper layer of the skin for deep hydration and nutrient replenishment. At Dermaestet it is used as prevention against ageing and to revive dehydrated, tired or maturing skin, restoring firmness, moisture and radiance without a scalpel. The clinic reports an effect lasting up to around six months, and it suits the face, neck, décolletage and hands.

Polynucleotide (PDRN) salmon DNA mesotherapy — a biological regenerative treatment injected into the dermis to activate tissue repair, stimulate fibroblasts, improve skin hydration, and reduce fine lines through cell regeneration.