Mesotherapy in Czechia

Facial mesotherapy at DiVine Clinic delivers a concentrated blend of hydrating and rejuvenating substances — including hyaluronic acid, vitamins, minerals, and amino acids — directly into the skin via fine micro-injections administered by MUDr. Petra Moravcová. Unlike topical skincare that must penetrate the skin barrier from outside, mesotherapy bypasses the stratum corneum entirely, placing active ingredients precisely in the dermis where they can immediately influence fibroblast activity, skin hydration, and overall skin quality. The injection forms small papules that are barely visible and absorb within 1–2 days, leaving behind improved radiance, elasticity, and suppleness. The eye area treatment is specifically formulated for the delicate periorbital skin, addressing dark circles, fine lines, and under-eye crepiness. Polynucleotides (PDRN) are available as an option within the mesotherapy menu for patients who want a biostimulatory upgrade.

Mesotherapy for the under-eye area at Follow Clinic delivers low-molecular-weight hyaluronic acid directly into the delicate skin below the eye via micro-injections, improving hydration, skin thickness, and the appearance of dark circles caused by thin or dehydrated skin (rather than structural hollowing). At 4,900 Kč per session, it is a gentle, non-volumizing alternative to tear trough filler — ideal for clients with fine-textured periorbital skin. A series of 2–4 sessions spaced 2–4 weeks apart is recommended for cumulative benefit, with maintenance every 4–6 months thereafter.

Mesotherapy at Altos Klinika delivers tailored cocktails of vitamins, minerals, amino acids and hyaluronic acid into the skin of the face, eye area or scalp through superficial micro-injections, from 4,900 Kč per session. The clinic recommends a course of three treatments, and also applies mesotherapy to the body for contour and cellulite improvement.

Skin boosters at Formositas are lightly cross-linked hyaluronic acid injections that deliver deep dermal hydration and a lasting improvement in skin quality, elasticity and glow — without adding volume the way classic fillers do. The clinic uses several certified brands (Dorothy, Neauvia Hydro Deluxe, Revitrane and the SkinFill Bacio lip booster) and publishes per-product pricing, so clients know exactly what is being injected and what it costs.

Mesotherapy neck and décolletage rejuvenation at Estetické centrum Komfort in Jihlava delivers microinjections of hyaluronic acid, vitamins and revitalising agents directly into the superficial dermis of the neck and chest area. The injections are administered by dermatologists using fine needles or the Vital Injector device, which distributes many simultaneous microinjections in a single stamp-action — reducing patient discomfort and increasing treatment consistency. The result is deep skin hydration, improved elasticity, softening of fine wrinkles and reduction of age spots.

Microinjection of vitamins, minerals and hyaluronic acid for facial rejuvenation.

Intradermal injection of salmon-derived polynucleotide (PDRN) gel at CLED — a viscoelastic, biocompatible DNA fragment preparation that hydrates and nourishes dermal fibroblasts, improving skin elasticity and firmness through a trophic rather than purely volumising mechanism. The single-use sterile gel is injected with a fine needle across any skin area including the delicate eye region, forehead, cheeks and full face. PDRN has documented effects on fibroblast proliferation and tissue repair, making it particularly useful for skin that is thin, damaged or slow to recover.

Hyaluronic acid skinbooster injections at CLED deliver a hydrating HA preparation with built-in lidocaine directly into the mid-dermis, creating a deep moisture reservoir that plumps and revitalises from within — an effect that topical serums cannot replicate. A single session takes up to 20 minutes and the deep hydration lasts 9–12 months. Treatment areas include face, hands, neck and décolletage. The gradual onset over three weeks means no immediate swelling visible to others, making it suitable for patients with no downtime.

Hair mesotherapy at Petra Clinic delivers a growth-stimulating active cocktail — including stem cell extracts, peptides, vitamins and minoxidil derivatives — via scalp microinjections directly at the level of the hair follicle. Bypassing the skin barrier to place active molecules beside the follicular bulge and papilla produces a degree of follicular stimulation that topical formulations cannot match. The clinic includes a free trichological examination in the initial consultation, using a specialist microscope to map hair loss distribution and density before determining the injection protocol. Results typically become visible within one to four months as hair shedding decreases and new anagen fibres emerge.

Hair mesotherapy at Klinika Esthé uses micro-injections of vitamins, peptides and revitalising nutrients into the scalp to support hair follicle nutrition and may help slow diffuse thinning. The 20–30-minute session is performed by a physician and pairs naturally with the clinic's FUE hair transplantation programme — either as a standalone option for early thinning or as supportive care around a transplant. Minimal downtime; patients can return to normal activities the same day.

An injectable skin-quality treatment that uses a high concentration of pure hyaluronic acid to remodel the skin from within rather than to add volume. Unlike a shaping filler, the bioremodeling product is designed to spread through the tissue, intensely hydrating it while stimulating the skin's own collagen and elastin. At this Brno practice it is used to improve hydration, firmness and the skin's mechanical properties, tightening fine wrinkles and giving a smoother, healthier-looking surface across areas such as the face, neck and hands.

A regenerative treatment that uses growth factors from your own blood to stimulate skin and hair renewal, sometimes called the 'Dracula' or vampire facial. A small blood sample is spun in a centrifuge to concentrate the platelet-rich plasma, which is then injected back into the skin using a mesotherapy technique to harness the body's own healing signals. At this Brno practice it is used for facial rejuvenation, hair loss, regeneration after laser, cryo or peeling, minor scars, lip modelling and rejuvenation of the neck, décolletage and hands.

Polynucleotide (PDRN) mesotherapy at BODY klinika using Rejuran — an injectable derived from salmon DNA fragments with high biocompatibility — delivered by fine micro-needle injections into the mesoderm layer of the skin. Polynucleotides stimulate the skin's own collagen and elastin synthesis rather than physically filling volume, progressively reducing fine lines, minimising pore size, and improving skin texture and radiance. Suitable for all skin types. Recommended protocol: three sessions at 3–4 week intervals, with maintenance every 6–12 months. From 5,000 Kč per session.

Platelet-rich plasma (PRP) therapy at AV Aesthetics uses the Arthrex ACP double-syringe system — a clinical-grade extraction device originally developed for orthopaedic and sports medicine that produces a highly concentrated, pure PRP fraction. A small volume of the patient's own blood is drawn, centrifuged using the Arthrex ACP protocol, and the resulting plasma — enriched with the patient's own growth factors — is re-injected into the target skin zones. The treatment may support skin regeneration, reduce the appearance of acne and acne scars, fine wrinkles, under-eye circles, and hyperpigmentation, and stimulate hair follicle activity. The initial protocol at this clinic involves three monthly sessions for optimal effect, followed by maintenance every 6–12 months.

Profhilo is an injectable hyaluronic-acid bio-remodelling treatment offered by Modrý pavilon's ophthalmology and aesthetics team. Unlike a volumising filler, Profhilo uses a highly purified, stabilised hyaluronic acid to hydrate the skin and support its quality and firmness across a treated area. It is delivered through a small number of precise injection points and is typically performed as a short course. A more advanced Profhilo Structura option is also available.

Polynucleotides (PDRN — PolyDeoxyRiboNucleotides) are DNA-fragment derivatives extracted from salmon DNA that stimulate skin cell regeneration at a molecular level. At Eva Clinic, MUDr. Chovančíková injects PDRN preparations into the mid-dermis, where they interact with cell-surface receptors (primarily A2A adenosine receptors) to activate fibroblast proliferation and collagen synthesis. The treatment is particularly well-suited to clients aged 30+ seeking to address the accelerating collagen breakdown phase of skin ageing, post-sun damage regeneration, and neck or décolletage quality improvements. Unlike HA fillers, polynucleotides work through biological signalling rather than volume addition, producing gradual but sustained improvements over a course of 2–3 sessions.

Biorevitalisation at Estetika by Medfima uses Jalupro Super Hydro — a premium injectable combining high-concentration hyaluronic acid with amino acids — to deeply hydrate and structurally restore skin from within. Delivered via microinjections by a licensed aesthetic physician, the treatment targets loss of volume, elasticity, and radiance associated with skin ageing and dehydration. The Pardubice aesthetic team tailors injection depth and technique to each individual's skin condition, with the eye area available as a separate protocol at a dedicated lower dose. Expect mild redness and transient swelling post-procedure, resolving within 24–48 hours. Most clients notice firmer, more luminous skin after the first session, with the full regenerative effect visible following the second treatment.

Derma Medical Clinic's skin rejuvenation programme combines three modalities — AquaShine hyaluronic-acid micro-injection mesotherapy, PRP plasma therapy and DermaPen microneedling — selected individually or in combination based on the patient's skin age and concerns. AquaShine delivers 15% hyaluronic acid in micro-injections for immediate plumping and long-term collagen stimulation; PRP uses the patient's own centrifuged blood plasma to flood the dermis with growth factors; DermaPen provides structural micro-channelling to deepen serum penetration. The goal is holistic skin quality restoration — improved hydration, firmness, tone and luminosity.

Intensive skin stimulation treatments delivered through the Vital Injector 2 system, combining a high-efficacy stimulator formula, peptide mesococktails, or platelet-rich plasma for deep dermal activation. The stimulator protocol targets multiple biological pathways simultaneously — collagen stimulation, hydration, and elastin production — with area options spanning the face alone through to face, neck, and décolleté in one session. Peptide cocktails address fine lines and firmness via targeted growth-factor-like signalling peptides, while the PRP option uses the client's own plasma for a fully autologous biostimulant result. A series of 3 sessions is recommended.

Facial mesotherapy at SKIN CARE Liberec delivers a customised cocktail of growth factors, vitamins, hyaluronic acid, and amino acids directly into the mesoderm layer of the skin — approximately 3 mm depth — using an ultra-thin needle protocol. Unlike topical serums, which cannot penetrate beyond the epidermis, mesotherapy bypasses the skin barrier entirely to deposit actives where they have direct cellular effect: stimulating fibroblasts to produce collagen, improving local microcirculation, restoring dermal hydration, and firming the tissue over a series of sessions. The cocktail composition is customised per patient depending on their skin condition and target concerns. Two to three treatments at three-to-four-week intervals constitute the standard course. A rest day is recommended after each session as mild swelling or bruising may occur.

Profhilo at GISANT is an injectable bio-remodelling treatment that uses a highly concentrated, stabilised form of hyaluronic acid to improve skin hydration, elasticity and firmness across an area — rather than adding volume like a traditional filler. It is delivered through a small number of precise injection points from which the product spreads to remodel the skin and stimulate collagen and elastin. A standard course is two sessions about four weeks apart, priced at CZK 5,400 for the first dose and CZK 4,900 for the second, with a group offer of CZK 4,400 each for four people. It suits patients wanting overall skin-quality improvement and subtle tightening rather than reshaping.

PRP Plasmatherapy at Beauty Clinic Synergy uses the Swiss RegenLab system to process a patient's own blood into a concentrated platelet-rich plasma and reintroduce it by injection into the face, scalp, neck, hands or body. The RegenLab protocol activates approximately 90 per cent of growth factors — roughly three times more than classic centrifuge methods — and yields approximately 5 ml of therapeutic plasma per draw. Physician-administered injections deliver the growth factors directly to fibroblasts and dermal tissue, stimulating collagen production, improving skin texture and reducing fine lines and scars over a course of 3–5 sessions.

Injectable lipolysis at Follow Clinic uses a phosphatidylcholine/deoxycholate compound injected directly into subcutaneous fat deposits to permanently destroy and dissolve localized fat cells. Targeted areas include the submental chin (from 3,500 Kč per session), abdomen and flanks (from 5,500 Kč), and inner thighs (from 7,200 Kč). Multi-session packages offer significant savings: up to 3 sessions for the abdomen at 15,000 Kč. Two to three sessions are typically needed for optimal contouring results. Swelling and redness in the treated area are expected for 1–2 weeks. Performed by a doctor.

Décolletage rejuvenation at S-thetics Beauty uses hyaluronic acid injections to improve the skin texture and reduce wrinkles of the chest and neckline area. The décolletage is chronically sun-exposed, often thinner-skinned than the face, and subject to vertical fold creases from sleep posture — all of which accelerate the appearance of ageing wrinkles, crepey texture, and pigmentation. MDDr. Šanšašvili uses a micro-injection technique across the chest area to deliver HA at the dermal level, providing deep hydration, improved elasticity, and a reduction in surface wrinkling. The treatment is available in 1 ml (5,500 Kč) or 2 ml (10,500 Kč) options depending on the area to be treated. A series of two to three sessions is recommended for optimal cumulative skin quality improvement.