4 Best Mesotherapy Clinics in Hradec Králové (2026)

Biorevitalisation at Estetika by Medfima uses Jalupro Super Hydro — a premium injectable combining high-concentration hyaluronic acid with amino acids — to deeply hydrate and structurally restore skin from within. Delivered via microinjections by a licensed aesthetic physician, the treatment targets loss of volume, elasticity, and radiance associated with skin ageing and dehydration. The Pardubice aesthetic team tailors injection depth and technique to each individual's skin condition, with the eye area available as a separate protocol at a dedicated lower dose. Expect mild redness and transient swelling post-procedure, resolving within 24–48 hours. Most clients notice firmer, more luminous skin after the first session, with the full regenerative effect visible following the second treatment.

Polynucleotide (PDRN) therapy at Estetika by Medfima uses purified salmon-derived DNA fragments injected into the dermis to promote deep cellular repair and skin regeneration. Unlike hyaluronic acid fillers that add volume, PDRN works by stimulating the skin's own repair machinery — activating fibroblasts, increasing collagen and elastin production, and promoting tissue oxygenation. The aesthetic team performs the treatment using fine needles or a cannula depending on the area, with anesthetic cream applied if needed. Separate protocols exist for the eye area and the full face, both at 4 500 Kč per session. Results are noticeable after the first session, with the full regenerative effect accumulating over a series.

Profhilo at Estetika by Medfima is an injectable skin remodelling treatment using one of the highest concentrations of hyaluronic acid available in any injectable product. Unlike conventional HA fillers, Profhilo is not cross-linked — it spreads throughout the tissue in a bio-remodelling action, stimulating the production of four types of collagen and elastin while delivering intense hydration. Two sessions four weeks apart are the standard protocol. Profhilo Structura, the deeper-tissue variant at 9 900 Kč, addresses the superficial musculoaponeurotic system (SMAS) layer for more pronounced tissue firming in clients with more advanced laxity. Results last up to 12 months and are notable for being completely natural — no added volume, no changed expressions.

Eva Clinic offers two complementary approaches to hair loss: scalp mesotherapy delivering vitamins, minerals, plant extracts, and amino acids directly into the scalp dermis, and Stem Aesthetic Hair Re!Growth Therapy — an advanced injectable treatment using stem cell-derived preparations to activate dormant hair follicles. MUDr. Chovančíková assesses the type and cause of hair loss at initial consultation — androgenetic, stress-induced (telogen effluvium), hormonal, or nutritional — to prescribe the appropriate treatment protocol. Both approaches improve scalp microcirculation, deliver follicle-activating nutrients, and stimulate the follicular bulge stem cell population responsible for hair cycle re-entry.

Mesotherapy at Eva Clinic delivers a personalised cocktail of hyaluronic acid, vitamins A, C, E, and B-complex, amino acids, peptides, and antioxidants directly into the dermis via microinjections or Dermapen microneedling. The approach bypasses the skin barrier to deliver active ingredients at cellular level — the same substances that are largely wasted in topical products. MUDr. Chovančíková adapts the cocktail formulation to each client's skin condition and concerns: hydration deficit, fine lines, loss of radiance, or oxidative damage. A treatment course of 3–6 sessions produces cumulative improvement in skin luminosity, hydration depth, and fine line density that persists for several months with appropriate maintenance.

Polynucleotides (PDRN — PolyDeoxyRiboNucleotides) are DNA-fragment derivatives extracted from salmon DNA that stimulate skin cell regeneration at a molecular level. At Eva Clinic, MUDr. Chovančíková injects PDRN preparations into the mid-dermis, where they interact with cell-surface receptors (primarily A2A adenosine receptors) to activate fibroblast proliferation and collagen synthesis. The treatment is particularly well-suited to clients aged 30+ seeking to address the accelerating collagen breakdown phase of skin ageing, post-sun damage regeneration, and neck or décolletage quality improvements. Unlike HA fillers, polynucleotides work through biological signalling rather than volume addition, producing gradual but sustained improvements over a course of 2–3 sessions.

Scalp mesotherapy delivering growth factors, vitamins, peptides and amino acids via microinjections directly into the scalp to support hair follicle health and stimulate new growth. Luna Klinik's hair mesotherapy protocol targets the follicular unit in the dermal papilla, supplying nutrients that are often deficient in thinning scalps and signalling dormant follicles back into the active growth phase. Sessions run 30–45 minutes and start at 3,000 Kč. A course of 4–6 sessions spaced 2–3 weeks apart is recommended, with monthly maintenance to sustain results.

Platelet-rich plasma (PRP) therapy using the patient's own blood to deliver concentrated growth factors directly into the skin, stimulating collagen, elastin and cellular renewal. Luna Klinik offers several plasma protocols — from a single-vial standard lift (3,890 Kč) to the RegenPlasma advanced variant, Endoret tubes and the 'Elixir of Youth' combining plasma with 1.5 ml hyaluronic acid. A small blood draw is taken on-site, centrifuged to isolate the growth-factor-rich fraction, then microinjected into the target area — face, neck or décolletage. The procedure takes 60–90 minutes and is well suited to patients with skin laxity, loss of elasticity, fine lines or early volume loss.

Injectable biorevitalization using a range of next-generation skin actives — hyaluronic acid, polynucleotides (Rejuran), exosomes, RRS cocktails with peptides and vitamins — delivered via fine-needle microinjections directly into the dermis. At Luna Klinik practitioners select the protocol by skin concern: RRS hydration for dryness and dullness, polynucleotides for deep skin repair and elasticity, exosomes for advanced cellular renewal. The under-eye area can be treated from 1,900 Kč; the Spanish Glow dual-product protocol (8,400 Kč) combines two RRS products for intense luminosity. Sessions run 60–90 minutes.