Mesotherapy in Písek

Scalp mesotherapy with Dermaheal HL serum delivers a complex of 56 bioactive ingredients — including biotin, peptides, growth factors, vitamins and amino acids — directly into the scalp via fine micro-injections. This bypasses the stratum corneum barrier that limits topical hair products, placing the active ingredients in immediate contact with hair follicles and the dermal papilla. The treatment supports hair follicle nutrition, improves scalp micro-circulation and may help reduce hair loss while stimulating dormant follicles toward active growth. At DermaClinique Písek, scalp mesotherapy is administered by MUDr. Jůzlová, Ph.D., using Dermaheal HL — a Korean-formulated serum produced for medical mesotherapy use.

Stem C'rum scalp mesotherapy uses a premium serum containing stem cell-derived growth factors and bioactive peptides to revitalise hair follicles and support new growth. The Stem C'rum serum (Stem Cell HL series) is a step above the Dermaheal HL formulation — it specifically incorporates stem cell conditioned medium, which contains the paracrine signalling molecules (cytokines, exosomes and growth factors) released by stem cells during culture. These signals activate follicular stem cells in the bulge region of the hair follicle — the reservoir of hair-regenerating capacity. At DermaClinique Písek, this premium treatment is administered by MUDr. Jůzlová, Ph.D. for patients wanting the highest-grade scalp biostimulation available.

Medical scalp mesotherapy for hair loss — a procedure in which a cocktail of active substances is introduced into the scalp's dermal layer using the Dermica Pen microneedling device. The micro-channels created by the pen's fine needles deliver the active compounds directly to the base of each hair follicle, bypassing the barrier of the scalp's outer layer and achieving local concentrations that topical products cannot match. Conditions addressed include androgenetic alopecia (genetic hair thinning), stress-related hair loss, hormone-related shedding, nutritional deficiency hair loss, and poor scalp circulation. At Dermo Písek the protocol may be combined with biostimulatory laser and is overseen by the clinic's dermatovenerology team.

PDRN-VITARAN is a Korean polynucleotide (PDRN — polydeoxyribonucleotide) biostimulator derived from salmon DNA fragments. When micro-injected into the periorbital area, the polynucleotide molecules bind to specific receptors (A2A adenosine receptors) in skin fibroblasts, triggering cellular regeneration, collagen synthesis and improved micro-circulation. The eye area treatment targets crow's feet, under-eye fine lines, dark circles caused by poor micro-circulation, and skin thinning in the periorbital zone — one of the earliest and most delicate areas to show age-related change. At DermaClinique Písek, 1 ml is used per session, administered by MUDr. Jůzlová, Ph.D.

Full-face PDRN-VITARAN biostimulation uses 2 ml of Korean polynucleotide solution micro-injected across the entire face to trigger collagen synthesis, improve micro-circulation and support tissue regeneration. The treatment delivers a higher dose than the eye-area-only protocol, providing whole-face skin quality improvement: reduced fine lines, improved elasticity, brighter complexion and more even skin tone. PDRN (polydeoxyribonucleotide) works at a cellular level by activating fibroblast regeneration pathways — distinct from hyaluronic acid hydration alone. At DermaClinique Písek, MUDr. Jůzlová, Ph.D. administers the treatment using precise micro-injection technique built on her hospital-level injectable medicine training.