Type
Mesotherapy
Duration
50 min
What's included
3 deliverables in this treatment
- 2 ml PDRN-VITARAN micro-injected across the full face
- Pre-treatment skin assessment and personalised injection mapping
- Post-treatment skincare protocol and recommended session spacing
Full-face PDRN-VITARAN biostimulation uses 2 ml of Korean polynucleotide solution micro-injected across the entire face to trigger collagen synthesis, improve micro-circulation and support tissue regeneration. The treatment delivers a higher dose than the eye-area-only protocol, providing whole-face skin quality improvement: reduced fine lines, improved elasticity, brighter complexion and more even skin tone. PDRN (polydeoxyribonucleotide) works at a cellular level by activating fibroblast regeneration pathways — distinct from hyaluronic acid hydration alone. At DermaClinique Písek, MUDr. Jůzlová, Ph.D. administers the treatment using precise micro-injection technique built on her hospital-level injectable medicine training.
About this treatment
The full-face PDRN-VITARAN treatment extends the polynucleotide biostimulation protocol to cover the complete facial surface — cheeks, forehead, perioral area, chin and jaw — using 2 ml of HP VITARAN salmon-derived PDRN solution. This comprehensive dosing ensures fibroblast activation across the full dermal network rather than targeting isolated zones.
Mechanism — same science, whole face
PDRN molecules activate the A2A adenosine receptor on skin fibroblasts, stimulating: - Collagen and elastin synthesis (structural matrix rebuilding) - Angiogenesis (improved capillary circulation → better nutrition and glow) - Wound-repair cascade (accelerated cellular renewal) - Anti-inflammatory modulation (relevant for acne-prone and reactive skin)
Good to know
- Product
- HP VITARAN (salmon PDRN)
- Dose
- 2 ml full-face coverage
- Sessions
- 2–3 × 2–4 weeks apart
- Price
- 4 200 Kč per session
Who is this for?
Overall skin quality improvement, anti-ageing biostimulation, dull or lacklustre complexion, fine lines, acne scars, summer-safe rejuvenation
Preparation required
Avoid aspirin and ibuprofen 1 week before. Come without make-up. EMLA numbing cream available for +100 Kč.
About the clinic
Reviews, team and credentials
Independent review links and clinic-reported team information.
Clinical team
DermaClinique Písek is founded and led by MUDr. Kateřina Jůzlová, Ph.D. She graduated from the 1st Medical Faculty of Charles University, completed her dermatovenerology residency and worked at the dermatovenerology clinic at Na Bulovce Hospital (2009–2017) and then at the dermatovenerology ambulance at IKEM (2015–2017), contributing to teaching, research and clinical studies. She was awarded her Ph.D. from the 2nd…
Languages: Czech
Treatment highlights
- 2 ml PDRN-VITARAN micro-injected across the full face
- Pre-treatment skin assessment and personalised injection mapping
+1 more item in What's included
4 200 Kč per session (2 ml PDRN-VITARAN product covering the full face). Recommended course: 2–3 sessions spaced 2–4 weeks apart, totalling 8 400–12 600 Kč. Maintenance every 3–6 months.