Profhilo — Bioremodeling (1 session)

Profhilo bioremodeling injection — high-concentration HA that hydrates deeply and stimulates collagen and elastin across four skin layers from just five injection points, improving skin quality without adding volume.

Profhilo at Upgrade Clinic is priced at 6,000 CZK for a single session (240 EUR), with a two-session course totalling 11,000 CZK (440 EUR). The standard protocol is two sessions four weeks apart, constituting the primary treatment course; a single annual maintenance session at six months sustains the collagen and elastin stimulation benefits. The product's thermal stabilisation technology — which creates a stable hybrid complex of high and low molecular weight HA without synthetic cross-linkers — allows it to spread through the subcutaneous tissue from just five injection points per side of the face (the Bio Aesthetic Points protocol). This gives Profhilo a uniquely broad tissue-coverage efficiency: 2 ml per session treats the full face from ten injection points, compared to the 30 to 40 microinjections typically needed for conventional mesotherapy to achieve similar coverage. At Upgrade Clinic, Profhilo is used primarily for facial skin quality improvement — addressing the combination of early laxity, dehydration, and loss of elasticity that characterises the mid-30s to mid-40s skin ageing trajectory. It is also suitable for the neck and décolleté, which are often undertreated but highly responsive to biostimulation. The absence of volumising effect means Profhilo does not change facial shape or create the risk of over-filled appearance — it purely improves the quality and resilience of existing skin tissue. At 6,000 CZK per session — versus 400 to 600 EUR per session in Germany or the UK for the same product and protocol — Upgrade Clinic offers a meaningful price advantage for medical tourists who can plan two sessions within a visit or return for maintenance sessions.