Mesotherapy (Mezolift)

Mesotherapy (mezolift) at EsteticUsti delivers a customised cocktail of vitamins, amino acids, and active compounds directly into the dermis via a series of micro-injections, bypassing the poor transdermal absorption that limits topical skincare. The technique was developed in France in the 1950s and refined over decades into the modern 'mezolift' protocols used today. By placing active ingredients precisely in the dermis — the skin layer responsible for structural integrity — mesotherapy achieves deep hydration, improved elasticity, and a brightness that topical products cannot replicate. At EsteticUsti, treatments target the face, neck, décolletage, and back of hands, with a separate scalp protocol for hair growth support.

The clinical rationale for mesotherapy rests on the pharmacological principle of bioavailability: topically applied vitamins and growth factors are largely blocked by the stratum corneum, never reaching the fibroblasts and dermal matrix where they would exert their regenerative effects. Intradermal microinjection delivers these compounds directly to the dermis at controlled concentrations, where they can stimulate fibroblast proliferation, upregulate collagen synthesis, improve microcirculation, and attract water molecules into the dermal matrix. The mesotherapy cocktails used at EsteticUsti — formulated under medical supervision — typically combine hyaluronic acid oligomers (for immediate hydration), vitamins C and E (antioxidants and collagen cofactors), B-complex vitamins (cellular energy metabolism), amino acids (collagen precursors), and growth factor peptides. The specific formulation is adjusted to the patient's skin condition and treatment goals at consultation. The procedure begins with application of a topical numbing cream for 40 minutes. The injections are then delivered via an automated applicator pen that administers multiple micro-doses in a systematic grid pattern across the treatment zone. The recommended protocol is: sessions 1 and 2 spaced one month apart, session 3 three months later, followed by maintenance at 3–4 sessions per year at 3-week intervals within each annual cycle. Recovery is rapid — normal activities resume within 2 hours to 1 day. Minor skin irregularities may be visible for up to 3 days; makeup should be avoided for 24 hours, and SPF is recommended. The hair mesotherapy protocol (scalp) targets follicular micro-circulation and nutrient delivery to stimulate growth and reduce telogen effluvium. Contraindications for all mesotherapy include active infections, fever, herpes labialis/zoster, acute skin infections, and sensitivity to any cocktail component.