Mesotherapy

Medical scalp mesotherapy for hair loss — a procedure in which a cocktail of active substances is introduced into the scalp's dermal layer using the Dermica Pen microneedling device. The micro-channels created by the pen's fine needles deliver the active compounds directly to the base of each hair follicle, bypassing the barrier of the scalp's outer layer and achieving local concentrations that topical products cannot match. Conditions addressed include androgenetic alopecia (genetic hair thinning), stress-related hair loss, hormone-related shedding, nutritional deficiency hair loss, and poor scalp circulation. At Dermo Písek the protocol may be combined with biostimulatory laser and is overseen by the clinic's dermatovenerology team.

FaceExpert's Skincare Consultation uses the Observ diagnostic system — a professional multi-spectral illumination device that reveals skin characteristics invisible under standard lighting — to give patients and the physician a complete, evidence-based picture of their skin health before selecting any treatment. The Observ uses six different light modes (including UV fluorescence and cross-polarisation) to assess surface texture, pore size, pigmentation depth, sebum distribution, and the condition of deeper skin layers. The session at FaceExpert includes a physician-led consultation, the Observ diagnostic imaging assessment, personalised treatment recommendations matched to the patient's actual skin biology rather than visible surface appearance alone, and skincare product recommendations from the clinic's SkinCeuticals range. At 1,500 Kč, this consultation is an accessible entry point for new patients and is recommended before committing to more intensive treatments such as chemical peels, laser, or RF microneedling. The consultation price is credited against the first treatment booked at the same visit.

Mesotherapy at Estetika Tábor delivers active compounds directly into the middle layer of the skin (mesoderm) using a fine-needle pen injector or traditional syringe, bypassing the barrier of the epidermis that limits topical skincare. Sessions at this clinic use pharmaceutical-grade serums including Dermaheal peptide complexes, Revitrane HA20 hyaluronic skinbooster, PROFHILO, and Genosys microneedling solutions — each targeting different skin concerns such as dehydration, fine lines, pigmentation, or overall radiance. Treatment costs 1,890 Kč per session for the face or décolletage and takes 15–80 minutes depending on the treatment scope selected. Clients typically return to normal activities the same day or next day after mild redness resolves.

Hair loss mesotherapy at Estetika Tábor delivers Dermaheal S. C'rum HL — a pharmaceutical serum containing 56 active substances including peptides, minerals, trace elements, and DHT-blocking compounds — directly into the scalp via microinjection. This bypasses the barrier effect of the scalp skin and places the active agents in direct contact with hair follicles and the dermal papilla, the vascular structure that determines follicle health and hair calibre. The treatment is suitable for clients experiencing excessive hair loss, diffuse thinning, or early-stage alopecia. A minimum course of 5 sessions at 14-day intervals is recommended, repeated twice yearly for ongoing maintenance. Sessions take 30–45 minutes and are performed by a physician.

Mesotherapy at DermaEsthetic delivers a cocktail of non-crosslinked hyaluronic acid and vitamins via micro-injections directly into the dermis, rapidly restoring skin hydration, elasticity and firmness. The treatment is carried out by MUDr. Hana Šulcová MBA, whose specialist background in aesthetic dermatology ensures precise depth targeting and personalised active-substance selection. Unlike superficial cosmetic facials, mesotherapy delivers bioactive ingredients exactly where skin cells need them — bypassing the barrier function of the epidermis for measurably superior hydration. Treatment areas include the face, forehead, chin, neck, décolletage and back of the hands, making it one of the most versatile rejuvenation options at the clinic.

PRP plasma therapy (platelet-rich plasma, also called plasma lifting) at Estetika Tábor uses the client's own blood to produce a concentrated growth factor solution that is microinjected back into the skin. The clinic extracts 10–20 ml of blood, centrifuges it to separate the plasma fraction rich in platelets and growth factors, and re-injects this autologous material into the face, décolletage, or scalp. The procedure triggers collagen synthesis, improves skin texture and hydration, and reduces fine lines and dark circles. Results develop over several weeks and last up to 12 months. Treatment takes approximately 50 minutes and is performed by a physician at the Světlogorská medical centre.

Skinbooster treatment at DiVine Clinic uses lightly cross-linked hyaluronic acid injected superficially via microcannulas to deeply hydrate the skin from within. Unlike volumising dermal fillers that add visible projection, skinboosters are designed to stay in the skin rather than create lift — dispersing evenly through the tissue to attract and hold water in the dermis, improving skin texture, luminosity, and elasticity. MUDr. Petra Moravcová applies numbing cream before the treatment; the session itself takes 15–20 minutes for the full face. A soothing aloe vera mask is applied post-treatment. Patients should arrive in good general health with no active skin inflammation. Small injection papules visible immediately after the session are normal and absorb within 24 hours. The result — plump, radiant, youthful-looking skin — is best maintained with repeat sessions every 3–6 months.

Mesotherapy at Esthetic Medical involves the microinjection of a customised cocktail of vitamins, hyaluronic acid, amino acids, and peptides directly into the dermis or subcutaneous layer, delivering active ingredients precisely where they are needed for maximum effect. The clinic is certified for mesotherapy and offers it for facial skin rejuvenation (hydration, fine line reduction, radiance), hair loss (stimulating follicle activity), and body treatments (cellulite, localised fat). Sessions take approximately 45 minutes and require no general anaesthesia — a topical cream is applied before the microinjections.

HydraFacial at FaceExpert combines six sequential steps in a single session: lymphatic drainage, deep cleansing, exfoliation using glycolic and salicylic acid blend, vacuum-assisted pore extraction via Vortex-Fusion technology, deep hydration delivery (hyaluronic acid and antioxidants), and LED light therapy via the LightStim Elipsa LED panel. The treatment is suitable for all skin types including sensitive, oily, dry, and problematic skin, with no downtime and immediate results visible. Three tier levels are available at FaceExpert — Standard (core protocol), Elite (adds LED and booster serum), and Expert (adds lymphatic drainage) — plus four signature variants targeting specific concerns: Men's Vitality, Clear Skin Anti-Acne, and Lymphatic Boost. The HydraFacial's Vortex-Fusion nozzle simultaneously exfoliates and infuses active serums, making it more effective than passive product application. Patients describe a significant visible improvement in skin clarity, hydration, and glow immediately after the session.

Mesotherapy at CLED delivers active cocktails — hyaluronic acid, amino acids, vitamins, botulotoxin or lipolytic compounds — via microinjections precisely into the target tissue layer, bypassing the skin barrier entirely for dramatically higher bioavailability than topical application. MUDr. Moskalyková offers multiple mesotherapy variants tailored to the clinical goal: MesoLift for face and neck revitalisation, MesoBotox for pore size and sebum control, MesoSculpting for localised fat reduction, Lipodissolve for fat deposit dissolution, and bio-rejuvenation cocktails for scalp, décolletage and hands.

Deep skin hydration and quality restoration using Revitrane HA20 skin booster (2 ml) or Fillmed mesotherapy cocktails, administered by MUDr. Irena Hejcmanová. Revitrane HA20 delivers non-cross-linked hyaluronic acid in high concentration directly into the dermis, creating a sustained hydration reservoir that improves elasticity, turgor and luminosity from within. Fillmed mesotherapy uses a proprietary blend of HA, vitamins, amino acids and minerals for broad-spectrum skin revitalisation. Numbing cream is included.

Mesotherapy at DermaStar delivers nutrient cocktails into the skin's middle layer (the mesoderm) via a series of microinjections, stimulating hydration, collagen production, and cellular regeneration without surgery. The clinic uses premium injectables including Dermaheal HSR — a formula containing 58 active substances (hyaluronic acid, amino acids, peptides, and vitamins) — as well as Neauvia and Redensity I pure HA. Treatments cover the face, neck, and décolletage. Three sessions at 2–4 week intervals are the standard course. Numbing cream is applied before treatment to minimise discomfort.

Superficial injection of non-crosslinked hyaluronic acid — alone or combined with vitamins, amino acids and trace ions — into the middle skin layer of the face, neck, décolletage or hands to restore deep moisture, improve skin elasticity and produce a hydrated, luminous complexion. Known as Mesolift when applied to the face and neck, this treatment delivers active ingredients directly to the dermis where topical products cannot penetrate, rebuilding the skin's hydration reservoir from within over a course of sessions. At Estetické centrum Praha MUDr. Renata Handlová uses ultra-thin 30–32 gauge needles and a specialist injector for consistent, uniform product distribution.

Facial mesotherapy at DiVine Clinic delivers a concentrated blend of hydrating and rejuvenating substances — including hyaluronic acid, vitamins, minerals, and amino acids — directly into the skin via fine micro-injections administered by MUDr. Petra Moravcová. Unlike topical skincare that must penetrate the skin barrier from outside, mesotherapy bypasses the stratum corneum entirely, placing active ingredients precisely in the dermis where they can immediately influence fibroblast activity, skin hydration, and overall skin quality. The injection forms small papules that are barely visible and absorb within 1–2 days, leaving behind improved radiance, elasticity, and suppleness. The eye area treatment is specifically formulated for the delicate periorbital skin, addressing dark circles, fine lines, and under-eye crepiness. Polynucleotides (PDRN) are available as an option within the mesotherapy menu for patients who want a biostimulatory upgrade.

Mesotherapy for the under-eye area at Follow Clinic delivers low-molecular-weight hyaluronic acid directly into the delicate skin below the eye via micro-injections, improving hydration, skin thickness, and the appearance of dark circles caused by thin or dehydrated skin (rather than structural hollowing). At 4,900 Kč per session, it is a gentle, non-volumizing alternative to tear trough filler — ideal for clients with fine-textured periorbital skin. A series of 2–4 sessions spaced 2–4 weeks apart is recommended for cumulative benefit, with maintenance every 4–6 months thereafter.

Intradermal injection of salmon-derived polynucleotide (PDRN) gel at CLED — a viscoelastic, biocompatible DNA fragment preparation that hydrates and nourishes dermal fibroblasts, improving skin elasticity and firmness through a trophic rather than purely volumising mechanism. The single-use sterile gel is injected with a fine needle across any skin area including the delicate eye region, forehead, cheeks and full face. PDRN has documented effects on fibroblast proliferation and tissue repair, making it particularly useful for skin that is thin, damaged or slow to recover.

Hyaluronic acid skinbooster injections at CLED deliver a hydrating HA preparation with built-in lidocaine directly into the mid-dermis, creating a deep moisture reservoir that plumps and revitalises from within — an effect that topical serums cannot replicate. A single session takes up to 20 minutes and the deep hydration lasts 9–12 months. Treatment areas include face, hands, neck and décolletage. The gradual onset over three weeks means no immediate swelling visible to others, making it suitable for patients with no downtime.

Injectable lipolysis at Follow Clinic uses a phosphatidylcholine/deoxycholate compound injected directly into subcutaneous fat deposits to permanently destroy and dissolve localized fat cells. Targeted areas include the submental chin (from 3,500 Kč per session), abdomen and flanks (from 5,500 Kč), and inner thighs (from 7,200 Kč). Multi-session packages offer significant savings: up to 3 sessions for the abdomen at 15,000 Kč. Two to three sessions are typically needed for optimal contouring results. Swelling and redness in the treated area are expected for 1–2 weeks. Performed by a doctor.

Polynucleotide biostimulation with PDRN (polydeoxyribonucleotide) at DiVine Clinic uses salmon-derived DNA fragments to activate dormant skin cells, stimulate collagen and elastin production, and restore elasticity, firmness, and hydration. Administered by MUDr. Petra Moravcová, PDRN is injected into the target skin zone — eye area, face, or neck and décolletage — where it acts on A2A adenosine receptors to trigger cell proliferation and tissue remodelling pathways. The treatment is an injectable biostimulator rather than a filler — it does not add visible volume but instead improves the quality of the skin's own structural matrix. DiVine Clinic offers courses of three sessions for each zone, with the eye area priced at 6,500 Kč and the face or neck at 8,500 Kč per session. Results are gradual and progressive, with visible improvement in skin elasticity, tone, and firmness over 4–8 weeks per session.

Plasma therapy (PRP) at DiVine Clinic uses the patient's own platelet-rich plasma to stimulate skin regeneration, collagen production, and tissue repair. MUDr. Petra Moravcová draws 8–10 ml of venous blood, centrifuges it to isolate the platelet-rich plasma fraction concentrated with growth factors, and re-injects the PRP into the target skin zone via fine needles or cannulas after numbing cream application. The growth factors released from activated platelets — PDGF, TGF-β, and VEGF — recruit fibroblasts to produce new collagen and elastin and improve local vascularisation. Because PRP is derived from the patient's own blood, the risk of allergy or immune reaction is essentially zero. The treatment is used at DiVine Clinic for facial skin rejuvenation, improved skin radiance, acne improvement, and hair loss treatment. Collagen remodelling begins below the surface within days, with visible skin quality improvement appearing over 6–8 weeks.

PRP plasma therapy at FaceExpert uses the patient's own blood — drawn, centrifuged to isolate the platelet-rich plasma fraction, and re-injected into the target tissue — to deliver a concentrated payload of growth factors that stimulate collagen production, improve skin quality, and support tissue regeneration. The treatment is completely autologous: because it uses the patient's own plasma, the risk of allergy or immune reaction is essentially zero. FaceExpert performs PRP with either 1 vial (6,900 Kč) or 2 vials (10,900 Kč) of processed plasma depending on the treatment zone and concentration needed. The therapy is used for facial skin rejuvenation, acne scarring, hair loss on the scalp, and general skin quality enhancement. Growth factors from activated platelets — PDGF, TGF-β, VEGF, EGF — trigger fibroblast proliferation, collagen synthesis, and angiogenesis. Visible improvement in skin luminosity and texture appears over 4–8 weeks per session, with 2–3 sessions recommended for sustained results.

Polynucleotide (PDRN) injections at FaceExpert use salmon-derived DNA fragments to activate natural skin cell regeneration — stimulating collagen and elastin production, improving tissue hydration, and evening skin tone without adding volume. PDRN acts on A2A adenosine receptors on skin fibroblasts and keratinocytes, triggering cell proliferation and tissue remodelling pathways backed by peer-reviewed clinical evidence. At FaceExpert, the treatment is applied to two primary areas: the eye contour (targeting the delicate under-eye skin for dark circle improvement and periorbital crepiness reduction) and atrophic scar treatment (particularly boxcar and rolling acne scars). Single sessions are available at 7,900 Kč, with 2- and 3-session packages offering meaningful savings. Results are progressive, appearing over 4–8 weeks per session as new collagen matures. Polynucleotide biostimulation is increasingly preferred over traditional mesotherapy by patients who want deeper skin regeneration without volumisation or the foreign-body response of synthetic fillers.

Profhilo at Esthé Laser Clinic is an injectable skin remodelling treatment using one of the highest concentrations of pure, stabilised hyaluronic acid available — 64 mg in 2 ml, formulated without BDDE cross-linking agents. Unlike conventional dermal fillers that add volume in targeted zones, Profhilo spreads bio-revitalising hyaluronic acid across a wide skin area via a patented NAHYCO Hybrid Technology matrix. It stimulates four types of collagen and elastin simultaneously, producing a deep moisturisation and firmness effect that transforms skin quality from within rather than augmenting or reshaping it. The protocol uses five precisely mapped injection points per side of the face (the BAP technique), minimising discomfort while maximising diffusion. Two sessions four weeks apart constitute the primary course; results are visible from the second week and continue improving for up to three months. Ideal for anyone noticing a loss of skin elasticity, laxity on the jawline or neck, or general dullness.

Biostimulation at FaceExpert uses two of the most clinically established collagen-stimulating injectables — Radiesse (calcium hydroxyapatite) and Sculptra (poly-L-lactic acid) — to trigger the skin's own collagen and elastin production without adding unwanted bulk volume. Unlike HA fillers that restore lost volume directly, biostimulatory injectables stimulate the tissue to regenerate itself: Radiesse (13,900 Kč) uses calcium hydroxyapatite microspheres suspended in a gel that is progressively replaced by new collagen over 12–24 months; Sculptra (14,900 Kč) uses PLLA microparticles where clinical studies demonstrate a 66.5% increase in collagen production in the first month alone. The result is progressive improvement in skin firmness, texture, and lift rather than immediate volumisation. MUDr. Macko's international training credentials make her a high-proficiency injector of both products. Both treatments are fully natural in origin and carry no allergy risk.