Type
Mesotherapy
Duration
45 min
What's included
4 deliverables in this treatment
- Medical consultation and skin quality assessment
- Profhilo 64 mg/2 ml product (BDDE-free hybrid HA)
- BAP technique injection at 10 anatomical points
- Post-treatment cooling and aftercare guidance
Profhilo at Esthé Laser Clinic is an injectable skin remodelling treatment using one of the highest concentrations of pure, stabilised hyaluronic acid available — 64 mg in 2 ml, formulated without BDDE cross-linking agents. Unlike conventional dermal fillers that add volume in targeted zones, Profhilo spreads bio-revitalising hyaluronic acid across a wide skin area via a patented NAHYCO Hybrid Technology matrix. It stimulates four types of collagen and elastin simultaneously, producing a deep moisturisation and firmness effect that transforms skin quality from within rather than augmenting or reshaping it. The protocol uses five precisely mapped injection points per side of the face (the BAP technique), minimising discomfort while maximising diffusion. Two sessions four weeks apart constitute the primary course; results are visible from the second week and continue improving for up to three months. Ideal for anyone noticing a loss of skin elasticity, laxity on the jawline or neck, or general dullness.
About this treatment
Profhilo belongs to the category of bioremodellers — a distinct class of injectable product from both traditional hyaluronic acid fillers and mesotherapy cocktails. Its defining characteristic is its concentration: 64 mg of hyaluronic acid in a 2 ml syringe, approximately double the HA concentration found in standard tissue fillers, yet without the BDDE (1,4-butanediol diglycidyl ether) cross-linking that makes conventional fillers volumetric and…
At Esthé Laser Clinic in Prague's Na Příkopě, Profhilo is administered by qualified medical practitioners using the BAP (Bio Aesthetic Points) technique: five injection points per side of the face, positioned at anatomically defined coordinates that allow the product to spread into multiple tissue planes without pooling. The points cover the cheek body, pre-jowl zone, chin, and midface. Each injection delivers the product precisely into the superficial…
Once in the tissue, the HA matrix acts as a scaffold that simultaneously stimulates fibroblasts to produce type I and type III collagen and elastin. The high-MW component of the hybrid provides the structural scaffold; the low-MW component drives the immediate bio-stimulating activity. The net effect, which becomes measurable at 4–6 weeks post-treatment, is a visible firming of the skin across the whole treated area — not a volumetric change, but an…
Good to know
- Product
- Profhilo 64 mg HA — BDDE cross-link free
- Technique
- BAP — 5 anatomical injection points per side
- Protocol
- 2 sessions × 4 weeks apart
- Mechanism
- Stimulates collagen types I & III + elastin
- Downtime
- Minimal — papules absorb within 1 hour
Who is this for?
Skin laxity, loss of elasticity, jawline or neck softening, dull or dehydrated skin, clients wanting quality improvement without volumetric augmentation
Preparation required
No blood-thinning medications or supplements 10 days before. No dental procedures 2 weeks prior. Clean, makeup-free skin on arrival.
About the clinic
Reviews, team and credentials
Independent review links and clinic-reported team information.
120 clinic reviews
From independent platforms
Clinical team
The clinic was founded by MUDr. Hana Raková, a dermatologist recognised as a pioneer of laser dermatology in the Czech Republic, with over 20 years of laser and aesthetic medicine practice. Clinical treatments including Botox injections and medical laser procedures are performed exclusively by qualified medical staff. The team holds certifications relevant to Candela laser platforms (V-Beam Perfecta, SMOOTHBEAM) and…
Languages: cs, en, de
What clients say
"{"author":"Google reviewer","text":"Professional clinic in a great location. Had Profhilo and the skin looks noticeably firmer and more hydrated. The team was attentive and the results speak for themselves.","source":"google"}"
"{"author":"Google reviewer","text":"I came for laser vascular treatment on my face and was impressed by how professional the whole process was. The doctor explained everything clearly, the treatment was quick, and the results were exactly what I hoped for.","source":"google"}"
Treatment highlights
- Medical consultation and skin quality assessment
- Profhilo 64 mg/2 ml product (BDDE-free hybrid HA)
+2 more items in What's included
8,000 Kč per session. Standard protocol is 2 sessions spaced 4 weeks apart for the full remodelling effect (16,000 Kč total course). Maintenance session recommended every 6–12 months. Price includes the Profhilo product and physician administration.