Mesotherapy

GUNA MD mesotherapy injections at Infinity Clinic use GUNA-brand homeopathic/biopuncture products — an Italian medical technology line that combines ultra-low-dose biologically active molecules (cytokines, growth factors, interleukins) with homeopathic dilution principles. Administered via intradermal or peri-articular micro-injection, GUNA MD products are used in the clinic's trauma-orthopaedic and rehabilitation context for pain modulation, joint and tendon support, and post-injury tissue recovery. At 600 Kč per dose, the treatment is a cost-effective adjunct to physiotherapy and orthopaedic care for patients seeking non-steroidal biological pain management.

Mesotherapy at MEDIKAP Pardubice delivers a customised cocktail of micro-nutrients — vitamins, hyaluronic acid, and growth factors — directly into the dermis via multiple shallow injections. By bypassing the epidermis, active substances reach their target tissue at concentrations unattainable through topical application. The treatment stimulates fibroblasts, increases collagen production, and restores dermal hydration. Priced at 1 300 Kč per session, it is one of the more accessible aesthetic treatments on the MEDIKAP menu. MUDr. Natálie Kaplanová selects the mesotherapy cocktail based on the patient's skin condition and goals, with a series of 3–6 sessions producing cumulative benefit.

Mesotherapy at Medest involves microinjections of a personalised cocktail of vitamins, hyaluronic acid, peptides, and minerals directly into the mid-layers of the skin — the mesoderm — where active ingredients have immediate bioavailability. Unlike topical serums that must penetrate multiple skin barriers, mesotherapy delivers nutrients precisely where skin regeneration occurs. MUDr. Vojtková applies mesotherapy to the face, neck, décolleté, and backs of hands to combat dullness, fine lines, dehydration, and early skin ageing. Sessions take approximately 45 minutes and the skin absorbs the active ingredients over the following 24–48 hours.

Mesotherapy at Estetika by Medfima delivers a customised blend of vitamins, enzymes, peptides, and other active ingredients directly into the mid-dermis via a series of microinjections, bypassing the skin barrier that prevents topical products from reaching the deeper layers where change actually occurs. The physician-formulated cocktails are tailored to each client's specific concern — anti-ageing, hydration, fine lines, scarring, stretch marks, pigmentation, or hair loss. Because the clinic does not charge a uniform price, the treatment can be precisely calibrated to each case rather than forcing clients into a standard package. Suitable for all skin types and ages. No adverse side effects are described; downtime is minimal.

Biorevitalization at Infinity Clinic delivers highly purified non-crosslinked hyaluronic acid and growth-stimulating compounds via micro-injections into the superficial dermis, restoring hydration, skin elasticity, and natural radiance. Unlike volumising fillers that add structural support, biorevitalization products (such as Restylane Skin Boosters or Juvederm Hydrate) act at the level of the dermis to attract water, stimulate collagen synthesis, and improve skin texture over time. MUDr. Petra Meluzinová, Ph.D., performs the treatment across the face, neck, décolletage, and hands. A standard course of 3 sessions spaced 3–4 weeks apart is recommended, with maintenance every 6 months.

Mesotherapy at OK Medical delivers personalised cocktails of unlinked hyaluronic acid, vitamins, plasma, and rejuvenating active ingredients directly into the dermis via microinjections — bypassing the skin barrier that limits topical skincare. Unlike filler HA (which is cross-linked and volumising), mesotherapy HA is thin and unlinked, spreading broadly through the dermis to improve hydration, firmness, and luminosity across entire zones rather than filling specific creases. The technique also allows addition of polynucleotides (DNA fragments that stimulate fibroblast activity) and exosomes (growth factor-rich cell signalling particles) for enhanced regeneration. Sessions last approximately 30 minutes; four sessions spaced for optimal long-term results.

Skinbooster treatment at MEDIKAP Pardubice uses micro-injections of low-viscosity hyaluronic acid to hydrate and restore elasticity across the skin surface rather than targeting specific lines or volumes. Available in two versions at MEDIKAP: the standard skinbooster (3 100 Kč) addresses superficial dermal hydration, while the deep skinbooster (5 800 Kč) penetrates to a greater tissue depth for more intensive restoration. The result is improved skin texture, radiance, and resilience — particularly beneficial for sun-damaged, dehydrated, or dull skin. A series of 2–3 sessions is recommended for optimal results, with maintenance every 6–12 months.

Mesotherapy and biorevitalization at Beauty Clinic Synergy inject active formulations — hyaluronic acid, amino acids, peptides, vitamins and brightening agents — directly into the dermis using fine needles or cannulas under topical anaesthesia. The clinic uses LinErase and SuneKOS, evidence-based European products, to match the cocktail to the patient's skin condition. Mesotherapy reaches the papillary dermis (2–4 mm) for surface hydration and texture improvement; biorevitalization penetrates the deeper reticular dermis (4–6 mm) with concentrated HA for structural plumping. Both are recommended in courses of 4–6 sessions every two weeks for cumulative benefit.

PRP plasma therapy at SKIN CARE Liberec uses the patient's own blood to extract and concentrate growth factors that regenerate skin tissue, stimulate collagen synthesis, and accelerate cell turnover. Between 10 and 20 mL of blood is drawn by the clinic's physician team, then centrifuged to separate the platelet-rich plasma from red cells. The concentrated plasma — loaded with PDGF, TGF-β, VEGF, and other bioactive proteins — is injected into the skin using fine needles after topical anaesthetic is applied. The autologous source means virtually no risk of allergic reaction. The standard course is two to three treatments: the second at four weeks, the third at two months, with results visibly improving three weeks after the series completes. Localised areas (eye, lips, cheeks) cost 3,700 Kč; full face or neck with included light therapy costs 7,500 Kč.

Hair mesotherapy at SKIN CARE Liberec delivers a bespoke growth-factor cocktail directly into the scalp via micro-injection to stimulate dormant hair follicles, improve follicle blood supply, and reduce the inflammatory processes underlying diffuse hair loss. The cocktail is individually formulated per patient following a diagnostic evaluation, and may include growth factors, vitamins (biotin, B-complex), amino acids, and scalp-specific minerals. Unlike topical products that cannot penetrate to follicle depth, scalp mesotherapy places the actives at exactly the depth needed — immediately adjacent to the follicle bulb and its supporting vasculature. Five sessions at one-to-two-week intervals constitute the standard course; results become visible at three to four months as hair density and thickness improve. Suitable for both men and women experiencing hereditary, diffuse, or circular alopecia.

ILK's mesotherapy formula contains 58 active ingredients delivered by micro-injection directly into the dermis — bypassing the epidermal barrier entirely. The cocktail includes biomimetic peptides, nanoencapsulated hyaluronic acid, amino acids, nucleic acids, vitamins, minerals, and coenzymes, all working synergistically to stimulate collagen production, restore skin hydration and improve elasticity. Unlike topical serums, intradermal delivery places these actives at the depth of the fibroblasts where they stimulate new collagen and elastin. The procedure uses fine needles; a consultation assesses skin condition and maps the treatment zones. Microneedling can be added for enhanced channel penetration.

Mesotherapy (mezolift) at EsteticUsti delivers a customised cocktail of vitamins, amino acids, and active compounds directly into the dermis via a series of micro-injections, bypassing the poor transdermal absorption that limits topical skincare. The technique was developed in France in the 1950s and refined over decades into the modern 'mezolift' protocols used today. By placing active ingredients precisely in the dermis — the skin layer responsible for structural integrity — mesotherapy achieves deep hydration, improved elasticity, and a brightness that topical products cannot replicate. At EsteticUsti, treatments target the face, neck, décolletage, and back of hands, with a separate scalp protocol for hair growth support.

Polynucleotide (PDRN) therapy at Estetika by Medfima uses purified salmon-derived DNA fragments injected into the dermis to promote deep cellular repair and skin regeneration. Unlike hyaluronic acid fillers that add volume, PDRN works by stimulating the skin's own repair machinery — activating fibroblasts, increasing collagen and elastin production, and promoting tissue oxygenation. The aesthetic team performs the treatment using fine needles or a cannula depending on the area, with anesthetic cream applied if needed. Separate protocols exist for the eye area and the full face, both at 4 500 Kč per session. Results are noticeable after the first session, with the full regenerative effect accumulating over a series.

Mesotherapy neck and décolletage rejuvenation at Estetické centrum Komfort in Jihlava delivers microinjections of hyaluronic acid, vitamins and revitalising agents directly into the superficial dermis of the neck and chest area. The injections are administered by dermatologists using fine needles or the Vital Injector device, which distributes many simultaneous microinjections in a single stamp-action — reducing patient discomfort and increasing treatment consistency. The result is deep skin hydration, improved elasticity, softening of fine wrinkles and reduction of age spots.

Derma Medical Clinic's skin rejuvenation programme combines three modalities — AquaShine hyaluronic-acid micro-injection mesotherapy, PRP plasma therapy and DermaPen microneedling — selected individually or in combination based on the patient's skin age and concerns. AquaShine delivers 15% hyaluronic acid in micro-injections for immediate plumping and long-term collagen stimulation; PRP uses the patient's own centrifuged blood plasma to flood the dermis with growth factors; DermaPen provides structural micro-channelling to deepen serum penetration. The goal is holistic skin quality restoration — improved hydration, firmness, tone and luminosity.

Biorevitalisation at Estetika by Medfima uses Jalupro Super Hydro — a premium injectable combining high-concentration hyaluronic acid with amino acids — to deeply hydrate and structurally restore skin from within. Delivered via microinjections by a licensed aesthetic physician, the treatment targets loss of volume, elasticity, and radiance associated with skin ageing and dehydration. The Pardubice aesthetic team tailors injection depth and technique to each individual's skin condition, with the eye area available as a separate protocol at a dedicated lower dose. Expect mild redness and transient swelling post-procedure, resolving within 24–48 hours. Most clients notice firmer, more luminous skin after the first session, with the full regenerative effect visible following the second treatment.

Facial mesotherapy at SKIN CARE Liberec delivers a customised cocktail of growth factors, vitamins, hyaluronic acid, and amino acids directly into the mesoderm layer of the skin — approximately 3 mm depth — using an ultra-thin needle protocol. Unlike topical serums, which cannot penetrate beyond the epidermis, mesotherapy bypasses the skin barrier entirely to deposit actives where they have direct cellular effect: stimulating fibroblasts to produce collagen, improving local microcirculation, restoring dermal hydration, and firming the tissue over a series of sessions. The cocktail composition is customised per patient depending on their skin condition and target concerns. Two to three treatments at three-to-four-week intervals constitute the standard course. A rest day is recommended after each session as mild swelling or bruising may occur.

Platelet-rich plasma (PRP) therapy at EsteticUsti uses the patient's own blood as the source material for a regenerative facial treatment. A small blood sample is centrifuged to concentrate the platelets — the cells whose primary function is wound healing and tissue repair — into a plasma solution 3–5 times richer in growth factors than normal blood. This concentrated PRP is then injected into the dermis of the face, neck, décolletage, hands, or scalp. The growth factors (PDGF, TGF-β, VEGF, IGF-1) activate resident fibroblasts and stem cells, driving collagen production, angiogenesis, and tissue regeneration from within. Because PRP is derived from the patient's own blood, the risk of allergic reaction is negligible.

PRP Plasmatherapy at Beauty Clinic Synergy uses the Swiss RegenLab system to process a patient's own blood into a concentrated platelet-rich plasma and reintroduce it by injection into the face, scalp, neck, hands or body. The RegenLab protocol activates approximately 90 per cent of growth factors — roughly three times more than classic centrifuge methods — and yields approximately 5 ml of therapeutic plasma per draw. Physician-administered injections deliver the growth factors directly to fibroblasts and dermal tissue, stimulating collagen production, improving skin texture and reducing fine lines and scars over a course of 3–5 sessions.

SkinBooster injections at SKIN CARE Liberec deliver cross-linked 20% hyaluronic acid deep into the dermis to achieve long-lasting internal hydration and skin quality improvement that topical products cannot replicate. Unlike standard HA fillers that add structural volume, SkinBooster is a low-viscosity, highly hydrophilic gel designed to integrate into the dermis and attract water molecules over time, progressively improving elasticity, radiance, and fine line texture. The protocol requires two to three sessions spaced approximately one month apart, with effect duration of six to eight months. A numbing cream is applied 30 minutes before each session. Areas include localised zones (eye area, lips, or cheeks) from 6,100 Kč, or larger areas (full face, neck, décolletage) at 12,200 Kč per session, with multi-session packages available.

Polynucleotide (PDRN/PN) biostimulation at Medest uses injectable DNA fragments derived from wild Korean salmon milt — highly purified and extensively biocompatibility-tested — to activate the skin's natural repair mechanisms from within. The polynucleotides bind to adenosine receptors in skin cells, triggering a cascade of regenerative processes: increased hydration, improved structural integrity, collagen and elastin stimulation, and measurable anti-inflammatory and antioxidant activity. Unlike hyaluronic acid fillers that add volume mechanically, polynucleotides work biologically — they do not fill or volumise but instead restore the functional quality of skin that has thinned or lost resilience with age. MUDr. Vojtková applies the treatment to the eye area, face, neck, and décolleté with results developing gradually over several weeks.

Profhilo at Estetika by Medfima is an injectable skin remodelling treatment using one of the highest concentrations of hyaluronic acid available in any injectable product. Unlike conventional HA fillers, Profhilo is not cross-linked — it spreads throughout the tissue in a bio-remodelling action, stimulating the production of four types of collagen and elastin while delivering intense hydration. Two sessions four weeks apart are the standard protocol. Profhilo Structura, the deeper-tissue variant at 9 900 Kč, addresses the superficial musculoaponeurotic system (SMAS) layer for more pronounced tissue firming in clients with more advanced laxity. Results last up to 12 months and are notable for being completely natural — no added volume, no changed expressions.

Profhilo is a pure stabilised hyaluronic-acid injectable that works as a bio-remodeler rather than a volumising filler: instead of adding volume at specific points, it spreads within the tissue after injection, attracting and binding water across a broad zone while stimulating the skin's own collagen and elastin production. The result is improved skin hydration, tone, texture and elasticity — a general quality uplift rather than targeted volume correction. At Derma Medical Clinic, Profhilo is used for dehydrated, tired, lax or textured skin of the face, neck and décolletage.

Polynucleotide (PDRN/PN) biostimulation injections at SKIN CARE Liberec deliver a highly purified preparation of long-chain DNA fragments — derived from salmon sperm or medical-grade plant sources — into the dermis to trigger deep cellular regeneration, improve skin hydration, and stimulate collagen and elastin synthesis through a receptor-mediated pathway. Unlike growth factor mesotherapy which delivers signalling proteins, polynucleotides work by activating the purinergic receptor (A2A) on fibroblasts, which upregulates the entire cellular repair programme — collagen synthesis, antioxidant defence, and ECM restoration — from within the cell. The treatment requires three sessions at monthly intervals for full effect. Pricing from 10,000 Kč for whole face; a three-session under-eye package is available at 15,000 Kč.