Mesotherapy — Face, Neck & Décolletage

Mesotherapy at Estetika by Medfima delivers a customised blend of vitamins, enzymes, peptides, and other active ingredients directly into the mid-dermis via a series of microinjections, bypassing the skin barrier that prevents topical products from reaching the deeper layers where change actually occurs. The physician-formulated cocktails are tailored to each client's specific concern — anti-ageing, hydration, fine lines, scarring, stretch marks, pigmentation, or hair loss. Because the clinic does not charge a uniform price, the treatment can be precisely calibrated to each case rather than forcing clients into a standard package. Suitable for all skin types and ages. No adverse side effects are described; downtime is minimal.

Mesotherapy is one of the oldest injectable techniques in aesthetic medicine, originating in France in the 1950s and refined extensively over subsequent decades. The fundamental principle remains unchanged: by bypassing the stratum corneum (the skin's waterproof outer barrier), injected active compounds reach the dermis at pharmacological concentrations — concentrations that topical application can never achieve. What has changed is the sophistication of the cocktails used and the precision of the delivery technique. At Estetika by Medfima, mesotherapy cocktails are customised by the treating physician at consultation. For facial anti-ageing and hydration, formulations typically combine cross-linked and non-cross-linked hyaluronic acid for structural and hydration effects, a B-complex vitamin blend (particularly B5, B6, B12), coenzyme Q10, amino acids including glycine and proline for collagen support, and peptide complexes such as acetyl hexapeptide for muscle-relaxing effects on expression lines. For pigmentation concerns, kojic acid, tranexamic acid, or ascorbic acid derivatives may be added to the cocktail. For scar and stretch mark treatment, fibroblast-activating enzymes and growth factors extend the protocol. The injection technique uses a mesotherapy gun or manual injection method with a very fine-gauge needle, delivering the cocktail across multiple micro-points spaced 1–2cm apart over the target surface. The face, neck, and décolletage can be treated in sequence in a single session. The treatment produces a transient erythema (redness) and occasionally small papules at injection points that resolve within a few hours; bruising is rare with the fine-gauge technique but possible. Clients can typically apply mineral makeup the next day. For hair loss (androgenic or diffuse alopecia), a separate scalp mesotherapy protocol delivers a cocktail of growth factors, minoxidil, vitamins, and DHT blockers directly into the scalp dermis in the thinning zones. The 5ml protocol (2 400 Kč) covers the full scalp; the 2.5ml protocol (1 500 Kč) is suitable for localised thinning. Hair mesotherapy is typically performed monthly for 4–6 sessions in the active phase, followed by quarterly maintenance. The absence of cross-linkers or synthetic polymers makes mesotherapy among the lowest-risk injectable procedures available. The clinic notes no adverse side effects for appropriately selected candidates; contraindications are limited to pregnancy, breastfeeding, blood-clotting disorders, and needle phobia. Sessions can be spaced 2–4 weeks apart depending on concern and cocktail composition, with most clients undergoing 4–6 sessions in a starting course before transitioning to quarterly maintenance. Mesotherapy pairs naturally with Profhilo, polynucleotides, or HA fillers in a multi-modality treatment plan — the Estetika team will advise on the optimal combination and sequencing at the initial consultation.