Microneedling

PRISTINE Diamond Microdermabrasion at Miracle Esthetic Clinic uses the Pristine™ device to mechanically exfoliate the outer epidermal layers with a diamond-tipped applicator while simultaneously applying gentle vacuum suction that stimulates blood flow, enhances oxygen delivery to the dermis, and promotes collagen and elastin production. The treatment addresses acne-prone skin, blackheads, stretch marks, scars, oily or congested skin, hyperpigmentation, sun damage, ingrown hairs, and mature skin — providing controlled epidermal renewal without chemical agents or downtime. It also serves as an effective preparation step before other skin treatments, enhancing their ingredient penetration.

Microneedling at Estetika Tábor uses a pen-type automated needling device to create thousands of controlled micro-channels in the dermis, combined with the simultaneous delivery of active serums — specifically Genosys (a Korean growth-factor complex) or Dermaheal peptide blends — directly into the puncture channels. This approach achieves two effects simultaneously: the mechanical micro-injury stimulates the skin's natural wound-healing response (collagen and elastin synthesis), while the serum infused into the channels works at the dermal level without the barrier resistance of intact epidermis. Sessions cost 1,890 Kč per zone (face or décolletage) and take 30–60 minutes with topical anaesthetic applied beforehand.

Skinology's microneedling with mesotherapy cocktail combines Dermapen microneedling — a controlled skin puncturing device that creates micro-channels in the dermis — with the application of a customised active ingredient cocktail matched to the client's primary skin concern. The mesotherapy cocktail is applied before and after the Dermapen pass, with the micro-channels dramatically improving the depth and uptake of active ingredients versus topical application alone. Four cocktail formulations are available: a tranexamic acid and vitamin C blend for pigmentation, a hyaluronic acid and B-vitamin mix for anti-ageing and hydration, a collagenase enzyme preparation for acne scars, and a hyaluronic acid, polynucleotide, and exosome combination for rosacea and couperose. The 75-minute session includes topical anaesthesia for comfort. A course of 3–5 sessions at 7–14 day intervals produces the most significant and lasting results.

Microneedling at Forever You pairs collagen-induction needling with next-generation exosome and polynucleotide serums, finished with a calming alginate mask. The micro-channels both trigger the skin's repair cascade and carry regenerative actives deep into the dermis — a strong option for texture, pores, fine lines and post-acne skin.

The exosome microneedling treatment at Skinology elevates the standard Dermapen protocol with the application of a concentrated exosome solution — extracellular vesicles derived from stem cells that carry growth factors, microRNAs, and signalling proteins capable of triggering multi-pathway skin regeneration. Unlike single-active mesotherapy cocktails, exosomes simultaneously address multiple skin concerns: they reduce inflammation (beneficial for rosacea and sensitive skin), stimulate fibroblast activity (collagen and elastin production for anti-ageing and scar remodelling), regulate melanin synthesis (for pigmentation correction), and support vascular normalisation. A defining feature of this protocol is that the exosome solution remains on the face for 12 hours after the session — the micro-channels remain open during this window, allowing sustained uptake of the bioactive cargo. The 60-minute session is slightly shorter than the mesococktail protocol because the pre-anaesthesia and double-cocktail application steps are streamlined. Course of 3–5 sessions at 7–14 day intervals.

Medical microneedling with mesotherapy cocktail at FaceExpert creates thousands of controlled micro-channels across the skin using fine sterile needles, then immediately delivers customised active ingredients — collagen-stimulating peptides, growth factors, hyaluronic acid, vitamins, or anti-pigment agents — directly into the dermis where passive product application cannot reach. The dual action triggers the wound-healing collagen cascade while flooding the tissue with bioactives that directly target the treatment concern. FaceExpert offers six distinct protocols: Anti-Age for rejuvenation, Anti-Pigment for hyperpigmentation, Anti-Acne for active breakouts and scarring, Glow Booster for radiance, Hair Plus for scalp stimulation and hair loss, and Eye Area for under-eye puffiness and fine lines. Each cocktail is composed for the specific concern, and an optional chemical peeling add-on (1,900 Kč) amplifies surface renewal when combined. Sessions take approximately 45–60 minutes with minimal redness resolving within 24 hours.

Microneedling at Skinity Clinic uses a precision medical microneedling device to create a controlled pattern of micro-channels in the skin, triggering a natural wound-healing cascade that stimulates new collagen and elastin production in the dermis. MUDr. Martin Bortlík performs or supervises all microneedling sessions, adjusting needle depth (0.5–2.5 mm) to the target concern and skin zone — superficial for brightening and texture, deeper for acne scarring and stretch marks. The procedure is performed with topical anaesthetic cream for comfort, and a therapeutic serum (hyaluronic acid, vitamin C, or PRP from the patient's own blood) is infused through the open channels immediately after needling to maximise absorption. Most patients experience 24–48 hours of redness similar to mild sunburn, after which skin looks noticeably smoother and more luminous.

Viora V20 V-FR (fractional radiofrequency) is a non-ablative skin resurfacing treatment that uses RF energy to create controlled micro-zones of deep collagen remodelling in the dermis, stimulating significant new collagen synthesis for improvement in skin texture, acne scars, stretch marks, and deep wrinkles. Unlike ablative laser resurfacing, V-FR does not remove the epidermis, so there is no open wound — downtime is minimal. At Miracle Esthetic Clinic, V-FR is one of the more intensive skin renewal options available, supported by clinical data showing 81% skin texture improvement after a single session.

Microneedling (mikrojehličkování) využívá jemné jehličky k vytvoření kontrolovaných mikro-kanálků v kůži, čímž spouští přirozenou hojivou kaskádu a tvorbu nového kolagenu. Na Swiss Esthetic se microneedling provádí lékařsky certifikovanými přístroji s nastavitelnou hloubkou vpichu 0,5–2,5 mm dle ošetřované oblasti a cíle. Procedura zlepšuje texturu pleti, redukuje jizvy po akné a strie, zmenšuje póry a zpevňuje kůži. V kombinaci s aplikací vitamínového séra nebo hyaluronové kyseliny se výsledky prohlubují díky zvýšené penetraci aktivních látek přes otevřené kanálky.

Medical microneedling at Esthé Laser Clinic uses a motorised needle device to create thousands of controlled microchannels in the dermis, triggering the skin's natural wound-healing response and driving a sustained collagen and elastin synthesis that improves skin texture, pore appearance, fine lines, and superficial acne scarring. Unlike cosmetic rollers used in home settings, the clinic's medical device achieves controlled depths of 0.5–2.5 mm with consistent needle entry angle and speed — critical factors for predictable results and safety. Topical anaesthetic is applied before the procedure to ensure comfort. Sessions take 45–60 minutes. The skin's healing cascade peaks at 4–6 weeks post-treatment, meaning visible improvements continue well after the session itself. A course of 3–6 treatments spaced 4–6 weeks apart delivers compounding collagen remodelling across multiple healing cycles.

Medical microneedling using an adjustable-depth needle applicator (0.25–2.5 mm) to create thousands of controlled micro-channels in the skin, stimulating the body's own collagen and elastin production. Laser Esthetic's dermatology team treats wrinkles, sagging skin, large pores, hyperpigmentation, rosacea, acne scars and stretch marks. Results are visible after the first session and accumulate over three to four treatments. A hyaluronic acid or whitening serum can be infused immediately post-needling for enhanced absorption.

Dermapen + Biorevitalization at Follow Clinic combines motorized microneedling with the transdermal application of a hyaluronic acid biorevitalization serum, delivered through the micro-channels created by the Dermapen for deep skin hydration, wrinkle reduction, and firming. At 4,200 Kč per session, this treatment improves skin moisture levels, elasticity, and radiance over a recommended series of 3 sessions. The HA serum — including vitamins and supporting actives — penetrates the dermis directly through the open microneedling channels before they seal, achieving far greater effect than topical application alone. Ideal for dehydrated or early-aging skin.

Dermapen + Exosomes at Follow Clinic pairs Dermapen microneedling with a topical exosome serum for advanced cellular regeneration and skin repair. At 4,200 Kč per session, this combination targets UV-induced damage, pigmentation, and textural irregularities. Exosomes — nano-sized extracellular vesicles carrying growth factors and signalling proteins — are delivered transdermally through the micro-channels created by the Dermapen, amplifying the skin's natural repair response. The stratum corneum, which normally blocks large molecules, is bypassed during the 20–30 minute open-channel window. A series of 3 sessions is recommended.

Medical microneedling at DiVine Clinic uses a precision motorised microneedling device with adjustable penetration depth to create controlled micro-channels in the skin, triggering the body's natural wound-healing response and stimulating new collagen and elastin production in the dermis. A numbing cream is applied before treatment for comfort; immediately after needling, a nutrient serum of vitamins and active substances is applied to penetrate through the open channels and enhance the result. A cooling and calming mask is applied at the end of the session. The treatment is suitable for enlarged pores, fine wrinkles, hyperpigmentation, rosacea, and acne scarring, and is appropriate for sensitive skin types where stronger modalities might be too aggressive. Redness lasts around 24 hours post-treatment. DiVine Clinic recommends 2–3 sessions spaced approximately one month apart for best results, with 3-session packages available at a discounted rate.

Dermapen 4 microneedling at RAJSKA Clinic uses the fourth generation of the industry-standard automated microneedling pen — with sixteen fine needles oscillating at up to 120 stamps per second — to create thousands of controlled micro-injuries in the dermis, triggering the skin's natural wound-healing cascade to produce new collagen and elastin. Unlike VIVACE RF, standard Dermapen microneedling relies entirely on the biological response to needling, without additional energy delivery, making it the gentler option with shorter recovery and a lower price point. Dermapen 4's speed and precision make it suitable for delicate areas including the periorbital zone and neck. Treats ageing, pigmentation, acne scarring, rosacea, and stretch marks.

Microneedling at Altos Klinika creates thousands of controlled micro-channels in the skin to trigger collagen induction and boost the absorption of active serums, at 4,900 Kč per area with a 3-session subscription for 14,990 Kč. An anti-fibrotic variant using PB enzyme serums targets scars and fibrotic skin changes.

VIVACE microneedle radiofrequency at RAJSKA Clinic delivers simultaneous mechanical collagen induction (from the microneedles) and thermal energy (from RF current between needle tips) into the precise dermis depth where collagen and elastin form. Unlike standard microneedling which relies only on wound-healing stimulus, VIVACE RF adds controlled heating to denature existing collagen, triggering a remodelling response that produces denser, more organised new collagen over four to six weeks. VIVACE is performed under topical anaesthetic and is suitable for all skin types, including darker skin tones where laser resurfacing carries pigmentation risk. The clinic offers combination sessions pairing VIVACE with polynucleotide injections for a significantly enhanced outcome.

Morpheus8 at Esthesia Clinic is an InMode RF microneedling device that combines deep microneedling with fractional radiofrequency energy to simultaneously remodel the dermis and stimulate collagen synthesis at depths of up to 8 mm — significantly deeper than surface-level RF or standard microneedling alone. The treatment targets skin laxity, deep wrinkles and folds, acne scarring, enlarged pores, uneven texture, and early jowl descent on both the face and body. A topical anaesthetic is applied before the session to ensure comfort; treatment takes 20–30 minutes per area. Morpheus8 is particularly valued for the combination of surface skin renewal (from microneedling) and deep structural tightening (from RF heating of the subcutaneous layer), making it effective for patients who want a visible lifting result without injectables or surgery.

Morpheus 8 at DiVine Clinic is a radiofrequency microneedling treatment that delivers thermal energy directly into the dermis and subcutaneous fat via a matrix of gold-tipped insulated microneedles — penetrating up to 7 mm deep, significantly further than standard microneedling devices. Manufactured by InMode, the Morpheus 8 platform combines the collagen-induction effect of microneedling with the deep tissue remodelling of fractional radiofrequency (RF), simultaneously tightening the skin surface and remodelling the fat layer underneath. MUDr. Petra Moravcová uses it for facial contouring, pigmentation reduction, fine wrinkle treatment, skin resurfacing, acne scar reduction, and post-liposuction skin laxity. An anaesthetic cream and local cooling are applied before treatment; redness lasts about 24 hours with swelling and possible scabbing resolving within 1–3 weeks. Sessions are typically repeated every 6–8 weeks.

Secret DUO at Formositas is a two-in-one platform combining fractional microneedle radiofrequency (insulated needles to 3.5 mm depth) with a 1540 nm Er:glass non-ablative laser — treating skin laxity, wrinkles, acne scars, pores and stretch marks from two directions in a single session. Sessions include 40 minutes of topical anaesthesia and a healing mask; face, neck and décolletage from 11,000 Kč.

Morpheus8 is an FDA-cleared radiofrequency microneedling device by InMode that delivers RF energy through insulated microneedles at programmable depths into the dermis and subcutaneous fat. At Lili Clinic, it is used to tighten lax skin on the face, neck, décolletage, jaw, and body, reduce submental fat, improve acne scarring, and stimulate deep collagen remodelling. Numbing cream is applied before the session; mild redness clears within 1–3 days and normal activities resume within 24–48 hours.

Morpheus 8 at FaceExpert is an InMode radiofrequency microneedling device that combines the collagen-induction effect of microneedling with deep RF thermal energy delivery — penetrating up to 7 mm, well into the subcutaneous fat layer. This dual mechanism simultaneously resurfaces the skin surface and remodels the deeper structural tissue, making Morpheus 8 uniquely suited to both skin quality improvement and body contouring applications. FaceExpert offers Morpheus 8 for the face, neck, décolletage, submental region, abdomen, arms, and knees — covering both facial rejuvenation and body skin tightening in one device. The surface treatment mode addresses texture, pores, and fine wrinkles; the deep mode targets fat remodelling, scar revision, and structural tightening. MUDr. Macko's team programmes depth and energy precisely for each zone, with topical anaesthesia applied before treatment. Redness lasts approximately 24 hours; minor scabbing resolves within 7–14 days. Three to four sessions spaced 6–8 weeks apart are typically recommended for optimal results.

Microneedle radiofrequency (MNRF) at Petra Clinic combines the skin-remodelling depth of fractional microneedling with the collagen-stimulating heat of radiofrequency energy. Arrays of ultra-fine insulated needles penetrate to a precisely set depth in the dermis, then discharge RF energy at the tip — heating collagen and elastin precisely where they sit, without damaging the overlying epidermis. This dual-stimulation approach treats wrinkles, acne scars, enlarged pores, post-pregnancy stretch marks and general skin laxity more effectively than either needling or RF alone. A topical anaesthetic is applied beforehand for comfort; most clients experience 2 days without makeup as the only noticeable post-treatment effect. A course of three sessions is standard.

The Genius Laser is Petra Clinic's most advanced microneedle radiofrequency device, distinguishing itself from conventional MNRF by incorporating real-time automatic energy control (AEC) that adjusts the RF output mid-pulse based on continuous tissue impedance readings. This closed-loop feedback prevents under- or over-treatment of variable skin layers, delivering a consistent thermal dose to the deep dermis regardless of regional skin thickness. Suitable for year-round use, the Genius Laser treats the face, neck and décolletage for wrinkles, skin laxity and scars, while its precision temperature management makes it safe across all skin phototypes. Expect approximately four days without makeup, versus the two days typical of standard MNRF.