Microneedling in Prague

PRISTINE Diamond Microdermabrasion at Miracle Esthetic Clinic uses the Pristine™ device to mechanically exfoliate the outer epidermal layers with a diamond-tipped applicator while simultaneously applying gentle vacuum suction that stimulates blood flow, enhances oxygen delivery to the dermis, and promotes collagen and elastin production. The treatment addresses acne-prone skin, blackheads, stretch marks, scars, oily or congested skin, hyperpigmentation, sun damage, ingrown hairs, and mature skin — providing controlled epidermal renewal without chemical agents or downtime. It also serves as an effective preparation step before other skin treatments, enhancing their ingredient penetration.

Skinology's microneedling with mesotherapy cocktail combines Dermapen microneedling — a controlled skin puncturing device that creates micro-channels in the dermis — with the application of a customised active ingredient cocktail matched to the client's primary skin concern. The mesotherapy cocktail is applied before and after the Dermapen pass, with the micro-channels dramatically improving the depth and uptake of active ingredients versus topical application alone. Four cocktail formulations are available: a tranexamic acid and vitamin C blend for pigmentation, a hyaluronic acid and B-vitamin mix for anti-ageing and hydration, a collagenase enzyme preparation for acne scars, and a hyaluronic acid, polynucleotide, and exosome combination for rosacea and couperose. The 75-minute session includes topical anaesthesia for comfort. A course of 3–5 sessions at 7–14 day intervals produces the most significant and lasting results.

Microneedling at Forever You pairs collagen-induction needling with next-generation exosome and polynucleotide serums, finished with a calming alginate mask. The micro-channels both trigger the skin's repair cascade and carry regenerative actives deep into the dermis — a strong option for texture, pores, fine lines and post-acne skin.

Medical-grade dermapen microneedling at My Best Care creates thousands of controlled micro-channels that trigger collagen production and dramatically boost absorption of active serums — refining texture, fine lines, enlarged pores and shallow scarring on the face, neck and décolleté. A salmon-DNA (polynucleotide) serum upgrade is available, and discounted 3-session courses are published.

Microneedling at DermaEsthetic uses single-use sterile needle cartridges to create thousands of controlled microchannels through the epidermis and into the dermis, triggering a wound-healing cascade that produces new collagen and elastin. Unlike laser-based remodelling, microneedling does not remove or ablate tissue — it is purely a stimulative microtrauma technique, making it suitable for a broader range of Fitzpatrick skin types including darker complexions where laser carries a higher hyperpigmentation risk. MUDr. Šulcová uses it for wrinkle reduction, facial contouring improvement, hyperpigmentation, rosacea management, acne scars and stretch marks.

The exosome microneedling treatment at Skinology elevates the standard Dermapen protocol with the application of a concentrated exosome solution — extracellular vesicles derived from stem cells that carry growth factors, microRNAs, and signalling proteins capable of triggering multi-pathway skin regeneration. Unlike single-active mesotherapy cocktails, exosomes simultaneously address multiple skin concerns: they reduce inflammation (beneficial for rosacea and sensitive skin), stimulate fibroblast activity (collagen and elastin production for anti-ageing and scar remodelling), regulate melanin synthesis (for pigmentation correction), and support vascular normalisation. A defining feature of this protocol is that the exosome solution remains on the face for 12 hours after the session — the micro-channels remain open during this window, allowing sustained uptake of the bioactive cargo. The 60-minute session is slightly shorter than the mesococktail protocol because the pre-anaesthesia and double-cocktail application steps are streamlined. Course of 3–5 sessions at 7–14 day intervals.

Collagen induction therapy with Dermapen for skin renewal.

Collagen induction therapy for skin rejuvenation, texture improvement, and scar treatment.

Medical microneedling with mesotherapy cocktail at FaceExpert creates thousands of controlled micro-channels across the skin using fine sterile needles, then immediately delivers customised active ingredients — collagen-stimulating peptides, growth factors, hyaluronic acid, vitamins, or anti-pigment agents — directly into the dermis where passive product application cannot reach. The dual action triggers the wound-healing collagen cascade while flooding the tissue with bioactives that directly target the treatment concern. FaceExpert offers six distinct protocols: Anti-Age for rejuvenation, Anti-Pigment for hyperpigmentation, Anti-Acne for active breakouts and scarring, Glow Booster for radiance, Hair Plus for scalp stimulation and hair loss, and Eye Area for under-eye puffiness and fine lines. Each cocktail is composed for the specific concern, and an optional chemical peeling add-on (1,900 Kč) amplifies surface renewal when combined. Sessions take approximately 45–60 minutes with minimal redness resolving within 24 hours.

Viora V20 V-FR (fractional radiofrequency) is a non-ablative skin resurfacing treatment that uses RF energy to create controlled micro-zones of deep collagen remodelling in the dermis, stimulating significant new collagen synthesis for improvement in skin texture, acne scars, stretch marks, and deep wrinkles. Unlike ablative laser resurfacing, V-FR does not remove the epidermis, so there is no open wound — downtime is minimal. At Miracle Esthetic Clinic, V-FR is one of the more intensive skin renewal options available, supported by clinical data showing 81% skin texture improvement after a single session.

Microneedling at Skinity Clinic uses a precision medical microneedling device to create a controlled pattern of micro-channels in the skin, triggering a natural wound-healing cascade that stimulates new collagen and elastin production in the dermis. MUDr. Martin Bortlík performs or supervises all microneedling sessions, adjusting needle depth (0.5–2.5 mm) to the target concern and skin zone — superficial for brightening and texture, deeper for acne scarring and stretch marks. The procedure is performed with topical anaesthetic cream for comfort, and a therapeutic serum (hyaluronic acid, vitamin C, or PRP from the patient's own blood) is infused through the open channels immediately after needling to maximise absorption. Most patients experience 24–48 hours of redness similar to mild sunburn, after which skin looks noticeably smoother and more luminous.

Microneedling (mikrojehličkování) využívá jemné jehličky k vytvoření kontrolovaných mikro-kanálků v kůži, čímž spouští přirozenou hojivou kaskádu a tvorbu nového kolagenu. Na Swiss Esthetic se microneedling provádí lékařsky certifikovanými přístroji s nastavitelnou hloubkou vpichu 0,5–2,5 mm dle ošetřované oblasti a cíle. Procedura zlepšuje texturu pleti, redukuje jizvy po akné a strie, zmenšuje póry a zpevňuje kůži. V kombinaci s aplikací vitamínového séra nebo hyaluronové kyseliny se výsledky prohlubují díky zvýšené penetraci aktivních látek přes otevřené kanálky.

Medical microneedling using an adjustable-depth needle applicator (0.25–2.5 mm) to create thousands of controlled micro-channels in the skin, stimulating the body's own collagen and elastin production. Laser Esthetic's dermatology team treats wrinkles, sagging skin, large pores, hyperpigmentation, rosacea, acne scars and stretch marks. Results are visible after the first session and accumulate over three to four treatments. A hyaluronic acid or whitening serum can be infused immediately post-needling for enhanced absorption.

Skin treatment promoting collagen production and overall skin regeneration.

Medical microneedling at Esthé Laser Clinic uses a motorised needle device to create thousands of controlled microchannels in the dermis, triggering the skin's natural wound-healing response and driving a sustained collagen and elastin synthesis that improves skin texture, pore appearance, fine lines, and superficial acne scarring. Unlike cosmetic rollers used in home settings, the clinic's medical device achieves controlled depths of 0.5–2.5 mm with consistent needle entry angle and speed — critical factors for predictable results and safety. Topical anaesthetic is applied before the procedure to ensure comfort. Sessions take 45–60 minutes. The skin's healing cascade peaks at 4–6 weeks post-treatment, meaning visible improvements continue well after the session itself. A course of 3–6 treatments spaced 4–6 weeks apart delivers compounding collagen remodelling across multiple healing cycles.

Dermapen + Biorevitalization at Follow Clinic combines motorized microneedling with the transdermal application of a hyaluronic acid biorevitalization serum, delivered through the micro-channels created by the Dermapen for deep skin hydration, wrinkle reduction, and firming. At 4,200 Kč per session, this treatment improves skin moisture levels, elasticity, and radiance over a recommended series of 3 sessions. The HA serum — including vitamins and supporting actives — penetrates the dermis directly through the open microneedling channels before they seal, achieving far greater effect than topical application alone. Ideal for dehydrated or early-aging skin.

Dermapen + Exosomes at Follow Clinic pairs Dermapen microneedling with a topical exosome serum for advanced cellular regeneration and skin repair. At 4,200 Kč per session, this combination targets UV-induced damage, pigmentation, and textural irregularities. Exosomes — nano-sized extracellular vesicles carrying growth factors and signalling proteins — are delivered transdermally through the micro-channels created by the Dermapen, amplifying the skin's natural repair response. The stratum corneum, which normally blocks large molecules, is bypassed during the 20–30 minute open-channel window. A series of 3 sessions is recommended.

Medical microneedling at DiVine Clinic uses a precision motorised microneedling device with adjustable penetration depth to create controlled micro-channels in the skin, triggering the body's natural wound-healing response and stimulating new collagen and elastin production in the dermis. A numbing cream is applied before treatment for comfort; immediately after needling, a nutrient serum of vitamins and active substances is applied to penetrate through the open channels and enhance the result. A cooling and calming mask is applied at the end of the session. The treatment is suitable for enlarged pores, fine wrinkles, hyperpigmentation, rosacea, and acne scarring, and is appropriate for sensitive skin types where stronger modalities might be too aggressive. Redness lasts around 24 hours post-treatment. DiVine Clinic recommends 2–3 sessions spaced approximately one month apart for best results, with 3-session packages available at a discounted rate.

Dermapen 4 microneedling at RAJSKA Clinic uses the fourth generation of the industry-standard automated microneedling pen — with sixteen fine needles oscillating at up to 120 stamps per second — to create thousands of controlled micro-injuries in the dermis, triggering the skin's natural wound-healing cascade to produce new collagen and elastin. Unlike VIVACE RF, standard Dermapen microneedling relies entirely on the biological response to needling, without additional energy delivery, making it the gentler option with shorter recovery and a lower price point. Dermapen 4's speed and precision make it suitable for delicate areas including the periorbital zone and neck. Treats ageing, pigmentation, acne scarring, rosacea, and stretch marks.

Microneedling at Altos Klinika creates thousands of controlled micro-channels in the skin to trigger collagen induction and boost the absorption of active serums, at 4,900 Kč per area with a 3-session subscription for 14,990 Kč. An anti-fibrotic variant using PB enzyme serums targets scars and fibrotic skin changes.

BB Perfect Skin is a nano-needle serum treatment that applies a certified German cosmetic serum into the outermost layer of the skin (stratum corneum — the dead cell layer) to unify complexion tone, add a natural radiance, and provide up to one year of skin-tone correction without the permanence of conventional micropigmentation. The serum contains light-reflecting mineral particles, vitamins B5, C, and E, almond and grapeseed oils, zinc oxide and titanium dioxide for UV protection, and magnesium sulfate for anti-inflammatory effect. It contains no PEGs, paraffins, or microplastics. Because the application reaches only the dead cell layer, the skin is not damaged and there is no recovery period. The treatment is suitable for uneven complexion, dull or fatigued-looking skin, redness, and loss of natural radiance. Two to three sessions four weeks apart give the most even cumulative result.

Skin tightening and rejuvenation using RF microneedling technology.

RF lifting at Impera Clinic combines microneedling with radiofrequency energy for intensive skin rejuvenation and firming. This technology stimulates collagen and elastin production, improves skin structure, reduces wrinkles and pores, and restores firmness and a youthful appearance. It is also effective for acne scarring and for improving overall skin texture and tone. An advantage of the treatment is minimal recovery time, with visible results after just a few sessions. RF microneedling is suitable for both women and men.

Vivace microneedle radiofrequency at My Best Care combines gold-tipped microneedling with fractional RF energy delivered in the dermis, tightening skin and stimulating collagen on the face, chin, neck, décolleté and body areas such as the abdomen and buttocks. A course of three sessions is recommended, with discounted 3-session packages published; results build over 3–6 months as new collagen matures.