Facial Rejuvenation in Prague

Botulinum toxin treatment for dynamic wrinkles - forehead, crow's feet, frown lines.

Luxury facial using SkinCeuticals products including CE Ferulic, Triple Lipid Restore, and A.G.E. Complex.

Professional facial treatment using ZO SkinHealth product line for targeted skin concerns.

Skinity Clinic is a certified HydraFacial operator, with treatments performed by Ondřej Pyrochta (Dis.) — a specialist trained specifically in the HydraFacial protocol. The HydraFacial Ultimate DeluXe is a three-step vortex-fusion treatment completed in approximately 30 minutes: hydro-dermabrasion exfoliation to remove dead skin, a gentle chemical peel combined with vacuum extraction to clear pores and remove blackheads, followed by infusion of a personalised booster serum (selected from antioxidants, peptides, hyaluronic acid, or brightening actives based on skin type) and LED light therapy with either red (collagen stimulation, anti-inflammatory) or blue (anti-bacterial, anti-acne) light. Suitable for all skin types with no downtime — the face is immediately radiant, hydrated, and smooth.

Medical-grade microneedling for face and décolletage — controlled micro-injuries stimulating collagen production, improving skin texture, reducing pore size, and addressing fine lines and mild pigmentation.

Esthesia Clinic offers the Moleqlar genetic proteomics test — a next-generation precision health assessment that goes beyond conventional DNA testing to analyse 6,500+ proteins currently being expressed in the body. While standard genetic tests reveal inherited DNA variants, proteomics measures what those genes are actually doing right now — identifying biological age, metabolic stress patterns, hidden inflammation, lifestyle impact scores (sleep, diet, exercise, stress), and early-risk signals for cardiovascular, metabolic, and inflammatory conditions. The test uses a saliva and blood sample collected at the clinic in minutes, with results returned in approximately four weeks. Interpretation sessions with a physician or nutritional therapist are available to translate the data into actionable health changes.

Botulinum toxin treatment for dynamic wrinkles.

Platelet-rich plasma therapy for facial rejuvenation, using the patient's own concentrated growth factors injected into the skin to stimulate collagen production, improve skin texture, and promote natural tissue regeneration.

Signature 75-minute Hollywood facial with heat dome, deep extraction, vacuum, galvanic current delivering Zinc and Vitamin C. No downtime.

Esthesia Clinic's Longevity Comprehensive Blood Panel is a wide-spectrum preventive blood test covering 30+ markers across metabolism, lipid health, liver and kidney function, inflammatory status, thyroid and hormonal balance, and key vitamins and minerals. The panel is designed for proactive health monitoring rather than diagnosing specific acute conditions, giving a detailed snapshot of biological function that can be tracked over time. Blood is drawn by a clinic nurse in a 10–15-minute appointment; results are emailed within approximately two business days. An optional add-on interpretation session with a nutritional therapist is available for 1,000 Kč additional, helping patients understand which results require dietary or lifestyle changes and which warrant physician follow-up.

Regenerative skin biostimulation using PDRN polynucleotides and Rejuran salmon-DNA, injected by Forever You's aesthetic medicine doctors. These purified DNA-fragment biostimulators are associated with improved skin repair, elasticity and thickness rather than added volume — a natural-results option for skin quality, eye-area rejuvenation and early laxity.

The dark circles treatment at S-thetics Beauty targets periorbital hyperpigmentation and under-eye volume loss — two of the most common and most visible signs of facial fatigue and ageing. The primary approach is hyaluronic acid tear trough filler (Stylage) placed along the orbital rim to restore volume in the hollow under-eye area, reducing the shadow that gives skin the dark, sunken appearance. Tear trough filler is one of the most technically demanding facial injection zones due to the thin skin, proximity to the eye, and complex anatomy of the inferior orbital rim — a zone where MDDr. Darina Šanšašvili's training in facial aesthetics and orofacial anatomy is directly applicable. Results are typically immediate and last six to twelve months. Consultation with MDDr. Šanšašvili establishes which component of the dark circle (volume loss, pigmentation, or both) is most prominent and which approach — filler, PRP, or a combination — is most appropriate.

IPL photorejuvenation at Formositas uses the BTL EXILITE III intense pulsed light platform with crystal cooling to treat sun damage, hyperpigmentation, broken capillaries and overall skin tone in one session — the full-face maximum-scope treatment combines photorejuvenation with vascular and pigment correction for 5,500 Kč. Smaller targeted areas, photoepilation and acne protocols are also available.

Complete facial treatment including iDerm, LED therapy, gel peel, and lifting massage for comprehensive skin renewal.

Lili Clinic offers one of the most comprehensive biostimulator menus in the Prague region, including Rejuran, Profhilo, Gouri, Radiesse, HArmoniCa, Plenhyage, Hyalift 75Pro, and Vitaran. These injectables stimulate the skin's own collagen and elastin production from within — unlike conventional fillers which simply add volume, biostimulators trigger biological regeneration and tissue remodelling. Sessions take 20–30 minutes with no downtime; effects develop over 4–6 weeks and last 6–18 months.

Microinjection of a concentrated cocktail of hyaluronic acid, vitamins, amino acids and coenzymes directly into the mesoderm (mid-layer of the skin) at approximately 4 mm depth, bypassing the epidermal barrier that prevents topical products from reaching target cells. Laser Esthetic uses Renophase Paris formulations for their mesotherapy protocols. Results — improved hydration, reduced fine lines and a visible glow — appear from the second day; normal activities resume the day after treatment.

Profhilo is the best-known injectable bio-remodelling treatment: ultra-high-concentration hyaluronic acid placed at a few strategic points spreads through the tissue to deeply hydrate, smooth surface wrinkles and tighten lax skin. Formositas also offers Profhilo Structura, the deeper variant that naturally restores volume lost through age-related fat tissue atrophy. The standard Profhilo protocol is two sessions a month apart; Structura takes one to two.

An extended PRP therapy session covering the face, neck, and décolleté for comprehensive rejuvenation across all visible ageing zones of the upper body.

Autologous PRP (platelet-rich plasma) treatment using the Cellular Matrix RegenLab system — a Swiss protocol that combines the patient's own plasma with hyaluronic acid before injection. Ten millilitres of blood is drawn, centrifuged to concentrate growth factors, mixed with an activator and injected via fine needles over a 10–15 minute session. Results become visible after two to three weeks and are sustained for eight to twelve months. A course of two to three sessions, 14–20 days apart, is recommended for optimal outcome.

Non-ablative Nd:YAG laser rejuvenation at Altos Klinika heats the dermis to stimulate collagen without breaking the skin surface, addressing early laxity, fine lines and dull tone with no social downtime. Single sessions cost 9,900 Kč for most face/neck/décolleté combinations and a discounted 3-session series is 19,900 Kč; IPL photorejuvenation for pigment and redness starts at 4,900 Kč.

The Longevity Personal Protocol at Esthesia Clinic is a comprehensive, physician-led preventive health programme that combines five diagnostic modalities into one coordinated 60–120-minute assessment. Participants undergo a full Longevity blood panel covering metabolic, hormonal, inflammatory, vitamin and immune markers; InBody 970 multi-frequency bioimpedance analysis measuring segmental muscle mass, visceral fat, cellular phase angle and metabolic age; MaxPulse cardiovascular and stress-resilience assessment measuring heart rate variability, vessel elasticity, and autonomic nervous system function; a Moleqlar proteomics genetic test analysing 6,500+ proteins for early disease signals and biological ageing factors; and a personalised consultation with a physician and nutritional therapist to synthesise findings into an actionable longevity plan covering lifestyle, supplements, nutrition, and clinical follow-up. The programme is best suited to proactive health managers, people with family history of cardiovascular or metabolic disease, and anyone seeking a rigorous baseline against which to track their biological age over time.

Hand rejuvenation at S-thetics Beauty restores lost volume to the backs of the hands using hyaluronic acid injections — the same Stylage filler technology used for facial volumisation. Age-related volume loss in the dorsal hand causes the skin to thin, the tendons to become prominent, and the veins to stand out visually, giving the hands an aged appearance that often contrasts with a refreshed face. Restoring volume with HA filler smooths the surface, reduces tendon and vein visibility, and improves skin texture. Two millilitres of filler per session typically covers both hands. MDDr. Darina Šanšašvili performs the procedure using a cannula or fine-needle technique, distributing the filler evenly to avoid lumpiness and achieve a natural result. Results last twelve months or more in the hand dorsum.

Beautification at Klinika Esthé is a planned, whole-face approach to injectable harmonisation: instead of treating one wrinkle or one lip, the physician analyses facial proportions and places small amounts of hyaluronic acid across several strategic points — cheekbones, chin, jawline, lips, temples or nose — to balance and refresh the face as a whole. The result is a rested, harmonious appearance rather than any single obviously 'done' feature. Pricing starts at 10,500 Kč and scales with the product volume the plan requires.

Non-surgical facial rejuvenation combining Alma Harmony's ClearLift Q-switched Nd:YAG technology with gentle remodelling laser energy — no needles, no ablation, no downtime. The Bio-Boost protocol delivers collagen stimulation, skin brightening, improved hydration and elasticity, and fine-line reduction in a single session. At Artmedica Clinic Prague the treatment is used as a premium alternative to injectable rejuvenation for patients who want meaningful skin improvement without recovery time or injection-related side effects. A Lip-Boost add-on targets perioral lines and lip definition using the same platform.