Hyaluronic Acid Dissolution — Filler Correction

Hyaluronic acid dissolution at S-thetics Beauty uses hyaluronidase enzyme injections to break down and reverse previously injected hyaluronic acid fillers — whether from S-thetics Beauty or another provider. Hyaluronidase is a naturally occurring enzyme that cleaves hyaluronic acid at the molecular level, causing the filler to dissolve within twenty-four to seventy-two hours. The treatment is used to correct overfilled areas, resolve filler asymmetry, address complications from previous injections (such as the Tyndall effect — a bluish discolouration from superficially placed filler), or fully reverse HA fillers where the client no longer wants the treatment. MDDr. Šanšašvili can also perform hyaluronidase as an emergency procedure to address suspected vascular compromise from filler — a rare but serious complication that requires immediate treatment. The dissolving process is typically complete within 48 to 72 hours, after which new filler can be placed if desired.

Hyaluronidase is a class of enzymes that catalyse the depolymerisation of hyaluronic acid — the sugar polymer backbone that gives HA fillers their gel-like structure. When injected in proximity to or directly into an existing filler deposit, hyaluronidase degrades the cross-linked HA chains in the filler, converting the solid gel into a soluble form that is cleared naturally by the tissue. The effect is rapid: within twelve to twenty-four hours of the injection, a noticeable reduction in filler volume is apparent; the full dissolution is typically complete within forty-eight to seventy-two hours. At S-thetics Beauty, hyaluronidase dissolution is available for several clinical scenarios. Filler correction — where a previous treatment produced asymmetry, overcorrection, or an undesired aesthetic outcome — is the most common use. Tyndall effect correction addresses the blue-grey skin discolouration that occurs when HA filler is placed too superficially in thin-skinned areas such as the tear trough or lips; dissolving the superficial deposit resolves the optical artefact. Full reversal is offered for clients who wish to return to their pre-filler appearance, whether due to aesthetic preference change or lifestyle reasons. MDDr. Šanšašvili can also perform hyaluronidase dissolution as an urgent medical intervention if there is any suspicion of vascular occlusion — the rare but serious complication where HA filler inadvertently compresses or enters a blood vessel, compromising tissue perfusion. This requires high-dose hyaluronidase administered immediately to dissolve the obstructing filler; the fact that this capability is available at the clinic is a significant patient safety consideration. Hyaluronidase preparations used in medical aesthetics are typically bovine-derived or recombinant. A skin allergy test is recommended for patients with known sensitivities to bee or wasp stings (which contain hyaluronidase) before the full dose is administered. The injection itself is performed by the same technique as a standard filler appointment: fine-gauge needle to the area of existing filler, with or without topical anaesthetic as needed. After hyaluronidase, the dissolved area may appear slightly deflated or uneven for forty-eight to seventy-two hours while the tissue re-establishes its natural structure. Any new filler treatment should be delayed at least two weeks to allow the hyaluronidase activity to fully clear and the baseline tissue volume to stabilise. Contraindications: known allergy to hyaluronidase or bovine proteins (an allergy test should be performed first), pregnancy, active infection at the intended injection site.