Hyaluronic Acid Dissolution — Filler Correction

Hyaluronidase is a class of enzymes that catalyse the depolymerisation of hyaluronic acid — the sugar polymer backbone that gives HA fillers their gel-like structure. When injected in proximity to or directly into an existing filler deposit, hyaluronidase degrades the cross-linked HA chains in the filler, converting the solid gel into a soluble form that is cleared naturally by the tissue. The effect is rapid: within twelve to twenty-four hours of the…

At S-thetics Beauty, hyaluronidase dissolution is available for several clinical scenarios. Filler correction — where a previous treatment produced asymmetry, overcorrection, or an undesired aesthetic outcome — is the most common use. Tyndall effect correction addresses the blue-grey skin discolouration that occurs when HA filler is placed too superficially in thin-skinned areas such as the tear trough or lips; dissolving the superficial deposit resolves…

MDDr. Šanšašvili can also perform hyaluronidase dissolution as an urgent medical intervention if there is any suspicion of vascular occlusion — the rare but serious complication where HA filler inadvertently compresses or enters a blood vessel, compromising tissue perfusion. This requires high-dose hyaluronidase administered immediately to dissolve the obstructing filler; the fact that this capability is available at the clinic is a significant patient…