Type
Facial Rejuvenation
Duration
30 min
What's included
3 deliverables in this treatment
- Choice of biostimulator product matched to skin indication (Rejuran, Profhilo, Radiesse, Gouri, Plenhyage, HArmoniCa, or Vitaran)
- Pre-treatment facial assessment and product selection consultation
- Post-treatment care instructions
Lili Clinic offers one of the most comprehensive biostimulator menus in the Prague region, including Rejuran, Profhilo, Gouri, Radiesse, HArmoniCa, Plenhyage, Hyalift 75Pro, and Vitaran. These injectables stimulate the skin's own collagen and elastin production from within — unlike conventional fillers which simply add volume, biostimulators trigger biological regeneration and tissue remodelling. Sessions take 20–30 minutes with no downtime; effects develop over 4–6 weeks and last 6–18 months.
About this treatment
Biostimulators and collagen stimulators are a distinct category of injectable skin treatment that activate endogenous regenerative processes rather than merely replacing lost volume. At Lili Clinic, the range covers several distinct biological mechanisms:
PDRN (Polynucleotide) products — Rejuran, Plenhyage, Vitaran
These products contain polydeoxyribonucleotides derived from salmon DNA, which are highly compatible with human tissue. PDRN activates A2A adenosine receptors, promoting cell proliferation, fibroblast recruitment, and collagen synthesis. Rejuran (2 ml face, 8,500 CZK) is the flagship Korean product in this category. Plenhyage (face 5,900 CZK; eye area 3,000 CZK) and Vitaran (eye area 3,000 CZK) are its Italian counterparts. All are used for facial skin…
Good to know
- Products offered
- Rejuran, Profhilo, Radiesse, Gouri, HArmoniCa, Plenhyage, Hyalift 75Pro, Vitaran
- Session time
- 20–30 minutes
- Downtime
- None — return to activities immediately
- Duration
- 6–18 months depending on product
Who is this for?
Skin laxity, early aging, dehydration, loss of facial radiance, skin quality improvement, under-eye treatment, scar remodelling
Booking options & clinic offers
Gift vouchers from 1,000 CZK available at objednavky.liliclinic.cz (6-month validity). Multi-area laser hair removal discount: 15% off 2 areas, 20% off 3+ areas.
About the clinic
Reviews, team and credentials
Independent review links and clinic-reported team information.
6 clinic reviews
From independent platforms
Clinical team
The medical team is led by MUDr. Hana Komrsová (board-certified dermatologist since 1997, specialising in cosmetic dermatology and laser procedures) and MUDr. Peter Jakubík (cardiologist and internist with cardiology attestation 2018, performing aesthetic medicine). MUDr. Zuzana Goldberg (graduated 2019) specialises in hair loss treatment and anti-aging. MUDr. Simona Sefzig (board-certified 2019) holds botulinum…
Languages: cs
What clients say
"{"author":"Blankachal","text":"Very satisfied, thank you.","source":"Firmy.cz","date":"2024-10"}"
"{"author":"Dajanapracuchova","text":"Great approach by the doctor.","source":"Firmy.cz","date":"2025-04"}"
Treatment highlights
- Choice of biostimulator product matched to skin indication (Rejuran, Profhilo, Radiesse, Gouri, Plenhyage, HArmoniCa, or Vitaran)
- Pre-treatment facial assessment and product selection consultation
+1 more item in What's included
Profhilo face 5,900 CZK. Plenhyage face 5,900 CZK. Plenhyage eye area 3,000 CZK. Hyalift 75Pro face 5,500 CZK. Rejuran face (2 ml) 8,500 CZK. Rejuran eye area 3,000–5,500 CZK. Vitaran eye area 3,000 CZK. Gouri (liquid PCL) 8,500 CZK. HArmoniCa (hybrid HA + CaHA) 18,000 CZK. Radiesse one area 10,500 CZK. Recommended course: 3–4 sessions at 2–3 week intervals.