Ozone Therapy in United States of America

Ozone autotransfusion at WholeHealth Chicago involves drawing a small volume of the patient's own blood, mixing it with a precisely calibrated ozone-oxygen mixture, and returning it intravenously — a method also known as minor autohemotherapy or major autohemotherapy depending on volume. Ozone therapy is used in integrative medicine as a modality associated with immune modulation and oxidative stress response. Sessions run approximately 30 to 45 minutes and are priced at $140 per session, with a minimum course of 10 sessions typically recommended. The clinic has offered ozone therapy since at least 2019.

iVitality MD Houston offers ozone therapy through three distinct modalities: IV ozone autohemotherapy (blood drawn, ozonated, and reinfused), HOCATT whole-body ozone sauna chamber sessions combining ozone steam with far-infrared heat and carbonic acid transdermal therapy, and EBOO — an advanced extracorporeal blood oxygenation and ozonation protocol. All sessions are physician-supervised and cash-based.

The HOCATT™ (Hyperthermic Ozone and Carbonic Acid Transdermal Therapy) sauna chamber combines ozone, carbonic acid gas, far-infrared heat, steam, and aromatherapy in a single full-body session. The multi-modal environment may support detoxification, circulation, and relaxation. Sessions run approximately 25 to 30 minutes with the patient seated inside the sealed chamber. Angel Longevity is one of a small number of LA-area clinics operating the HOCATT system.

Angel Longevity Medical Center offers ozone therapy and HOCATT (Hyperthermic Ozone and Carbonic Acid Transdermal Technology) infrared sauna sessions. HOCATT combines whole-body transdermal ozone exposure with carbonic acid therapy, infrared heat, and steam in a single session, supporting circulation, cellular oxygenation, and detoxification. All ozone protocols are administered under Dr. Mathur's supervision as part of a personalised integrative wellness plan.

Intravenous ozone therapy at Angel Longevity Medical Center involves the administration of a precisely measured ozone-oxygen mixture. Ozone is a reactive form of oxygen associated with supporting immune modulation and oxidative stress response in research contexts. Sessions typically complete within one hour under medical supervision. The clinic offers both standard ozone IV infusion and EBOO (Extracorporeal Blood Ozonation), a more advanced ozone protocol.

Medical ozone therapy using major autohemotherapy (MAH) — drawing a small volume of blood, mixing it with ozone gas, and reinfusing — alongside local ozone application and UV blood irradiation options. Associated with systemic antioxidant activation, immune modulation, and improved microcirculation. Physician-supervised at Patients Medical's Upper East Side NYC clinic. Sessions run 30–60 minutes.

WholeHealth Chicago's combined Ozone IV plus Ultraviolet Blood Irradiation (UVB) session pairs ozone autotransfusion with exposure of the patient's blood to ultraviolet light before re-infusion. UV blood irradiation — also called photobiomodulation or biophotonic therapy — has been used in integrative medicine as a complement to ozone therapy. The combined session is priced at $240 and is offered as the premium ozone protocol at the Lincoln Park clinic. Sessions run approximately 45 to 60 minutes.

Medical ozone therapy at StemWave Pro LA administered via IV autohemotherapy, rectal insufflation, localized injections, and topical application. Under Dr. Padra Nourparvar, DO, ozone therapy is used as a regenerative adjunct to stimulate immune response, reduce inflammation, and enhance tissue oxygenation. A course of 6–12 sessions is typically recommended. Located at Cedars Sinai Medical Office Towers in Los Angeles.

Revived offers two tiers of ozone treatment. Standard ozone+UVBI uses the TriVette device to infuse medical-grade O3 and expose blood to triple ultraviolet irradiation before returning it to the patient ($289/session). EBOO — Extracorporeal Blood Oxygenation and Ozonation — processes 2–4 litres of blood through a dialyzer with simultaneous ozone and oxygen infusion, the clinic's most intensive regenerative protocol ($1,500/session).

Ozone IV infusion at Infusion IV Lounge in Denver's Uptown neighborhood is a premium specialty treatment priced at $350 per session. Major autohemotherapy-style ozone administration is used to support immune modulation, antioxidant defense activation, and circulation. Available in-lounge at 663 E 19th Ave by registered nurses.

Extracorporeal Blood Ozonation and Oxygenation (EBOO) — also known as 10-pass ozone — circulates blood through an external circuit where it is treated with ozone before being returned to the body. More ozone exposure per session than standard major autohemotherapy. Associated with enhanced antioxidant response and immune modulation. Sessions run approximately 60–90 minutes under physician supervision at Patients Medical, New York City.

Medical ozone therapy at $1,099 per session. Ozone (O3) is administered via established protocols to deliver an oxidative stimulus supporting cellular response and recovery. Next Health Houston offers ozone therapy as part of its advanced medical services menu, requiring a physician consultation before treatment. Sessions approximately 60 minutes.

Next Health Century City offers EBOO — Extracorporeal Blood Oxygenation and Ozonation — one of the most advanced ozone protocols available in Los Angeles. Blood is drawn, ozonated through a medical-grade reactor, and returned via a dedicated IV line in a private suite. Sessions run 60–90 minutes with two IV lines in place. No fasting is required; hydration beforehand is recommended. A series of sessions is typically advised. Single sessions are priced at $1,099.

Ten-pass ozone therapy using an EBOO-style (Extracorporeal Blood Oxygenation and Ozonation) protocol in which blood is drawn, mixed with medical-grade ozone, and reinfused over multiple passes. May support immune function, circulation, and cellular energy. $1,099 per session at Next Health West Hollywood. Administered by clinical staff under physician supervision.

Next Health Aventura offers 10-Pass ozone therapy — an advanced blood ozonation protocol in which blood is drawn, saturated with medical-grade ozone, and reinfused through ten consecutive passes. This intensive protocol is administered under medical supervision and is sought for immune modulation, enhanced oxygen utilization, and detoxification support. Priced at $1,099, the 10-Pass is one of the most advanced ozone delivery methods available in South Florida.

Extracorporeal Blood Ozone and Oxygenation (EBOO) therapy at Next Health Bellevue, available at $1,099 per session. Blood is drawn, filtered through medical-grade ozone, and re-infused — combining ozone exposure with a filtration step that removes inflammatory byproducts. Approximately 60–90 minutes of active treatment time, with a total appointment of around 2 hours. Pre- and post-consultation included. Conducted in a private treatment suite at Lincoln Square North.

Medical ozone therapy at $1,099 per session at Next Health Buckhead, Atlanta. Ozone (O3) is administered via established protocols to deliver a controlled oxidative stimulus supporting cellular antioxidant response and recovery. A physician consultation is required before the first session. Sessions run approximately 60 minutes and are part of the clinic's advanced medical services tier.

Extracorporeal Blood Ozonation and Oxygenation (EBOO) passes blood through an external circuit where it is infused with ozone and oxygen before being returned to the body. Sessions cost $1,200 each or $3,500 for a three-pack. Appointments are 90 minutes with an active infusion time of 45-60 minutes, supervised by the clinic's regenerative medicine physician.

EBOO (Extracorporeal Blood Oxygenation and Ozonation) is an advanced ozone therapy at $1,499 per session in which blood is continuously drawn, passed through a specialised ozone reactor that simultaneously oxygenates and ozonates it, then returned to the patient. Processes a larger blood volume than major autohemotherapy. Requires physician clearance and labs before treatment at Next Health Houston.

OH Wellness Center is one of the few Houston clinics offering EBOO (Extracorporeal Blood Oxygenation and Ozonation)—a medical-grade ozone protocol that filters and ozonates 2–3 liters of blood outside the body before returning it. Sessions are conducted one-on-one with RN monitoring throughout. A G6PD lab result is required before the first session. Packages of 2–4 sessions are available at discounted rates. MAH (Major Autohemotherapy) ozone is also offered.

EBOO (Extracorporeal Blood Oxygenation and Ozonation) at $1,499 per session — an advanced ozone therapy at Next Health Buckhead, Atlanta, in which blood is continuously drawn, passed through a specialised ozone reactor that simultaneously oxygenates and ozonates it, then returned to the patient. Processes a larger blood volume than standard major autohemotherapy. Physician clearance and lab testing required before treatment.

EBO2 (Extracorporeal Blood Oxygenation and Ozonation) at Liondale Medical combines an apheresis machine with hemealumination — simultaneous exposure of blood to UVA, UVC, red, green, and blue light wavelengths — while ozone is infused. Used for autoimmune conditions, chronic infections, systemic inflammation, and brain fog. A highly advanced ozone-adjacent blood purification protocol offered by Dr. Bissoon in Manhattan.

Extracorporeal Blood Oxygenation and Ozonation (EBOO) therapy — an advanced ozone treatment in which blood is drawn from the body, passed through an ozone-infused oxygenation process using a medical dialysis-type filtration system, and returned to the patient. Sessions run approximately 60–90 minutes for the procedure with a total visit of approximately 2 hours. Price not published; contact Next Health Lincoln Park at (312) 624-7513.

Next Health Boston offers EBOO (Extracorporeal Blood Oxygenation and Ozonation), an advanced ozone therapy protocol confirmed for the Chestnut Hill flagship. In an EBOO session, blood is drawn out, passed through a medical-grade ozone and oxygen mixture in an extracorporeal circuit, then returned — a process that saturates red blood cells with ozone and removes circulating toxins and inflammatory compounds. It is used in the longevity space to support immune function, energy, and systemic detoxification.