Ozone Therapy (10-Pass)

Ten-pass ozone therapy using an EBOO-style (Extracorporeal Blood Oxygenation and Ozonation) protocol in which blood is drawn, mixed with medical-grade ozone, and reinfused over multiple passes. May support immune function, circulation, and cellular energy. $1,099 per session at Next Health West Hollywood. Administered by clinical staff under physician supervision.

Ozone therapy at Next Health West Hollywood is delivered as a ten-pass protocol inspired by the EBOO (Extracorporeal Blood Oxygenation and Ozonation) approach, in which the patient's blood is processed through an extracorporeal circuit where it is exposed to a precise, medically controlled concentration of ozone gas before being re-infused. In the ten-pass protocol, this process is repeated up to ten times in a single session, meaning significantly more blood volume is treated per appointment than in the single-pass major autohemotherapy approach. The ozone (O3) molecule is an unstable trioxygen species that reacts rapidly with biological molecules, including lipids, proteins, and nucleic acids; when introduced to blood in controlled therapeutic concentrations, it is thought to trigger a cascade of secondary reactive oxygen species (ROS) that, at non-cytotoxic levels, may activate antioxidant enzyme systems (catalase, superoxide dismutase, glutathione peroxidase), modulate inflammatory mediators, enhance oxygen delivery by improving red blood cell deformability and 2,3-DPG levels, and exert antimicrobial effects by direct oxidative damage to microbial membranes. The EBOO-style approach uses a closed, sterile extracorporeal circuit to separate plasma from red cells, expose the plasma fraction to ozone, and then recombine and reinfuse, which is associated with more complete ozone-plasma reaction and a larger volume of treatment compared to simple bubble exposure methods. Clients at Next Health West Hollywood typically pursue ozone therapy as part of a longevity protocol alongside NAD+ IV and HBOT. At $1,099 per session, the ten-pass protocol represents the clinic's most intensive single-session immune-supportive offering. Sessions are conducted by trained clinical staff with physician oversight.