EBOO Therapy (Extracorporeal Blood Oxygenation & Ozonation)

EBOO (Extracorporeal Blood Oxygenation and Ozonation) is an advanced ozone therapy at $1,499 per session in which blood is continuously drawn, passed through a specialised ozone reactor that simultaneously oxygenates and ozonates it, then returned to the patient. Processes a larger blood volume than major autohemotherapy. Requires physician clearance and labs before treatment at Next Health Houston.

EBOO — Extracorporeal Blood Oxygenation and Ozonation — is the most advanced ozone-based therapy available at Next Health Houston, priced at $1,499 per session and representing a significant step up in both treatment intensity and processed blood volume compared to standard major autohemotherapy. In EBOO, blood is drawn from one peripheral vein via a standard IV catheter and passed through a closed-circuit extracorporeal system that contains a specialised ozone reactor module. Inside the reactor, the blood is simultaneously exposed to high-concentration medical ozone and oxygen in a continuous-flow process, with the ozonated and oxygenated blood returned to the patient through a second IV line, creating a circuit. This extracorporeal approach allows a substantially larger volume of blood to be treated per session compared to batch major autohemotherapy protocols, in which blood is drawn into a bag, treated, then re-infused before the cycle repeats. The continuous-flow EBOO circuit also maintains a more consistent treatment environment throughout the session. The oxidative challenge delivered by EBOO triggers the same hormetic biological responses as standard ozone therapy — antioxidant enzyme upregulation, Nrf2 pathway activation, cytokine modulation, and improved oxygen utilisation — but at a greater systemic scale. Because of the extracorporeal blood handling involved, EBOO requires more thorough medical clearance than standard ozone therapy; patients must complete laboratory testing (including a full blood count and coagulation screening) and a physician consultation before the first session. The approximately 90-minute session is monitored throughout by clinical staff. EBOO is positioned at Next Health as an option for patients seeking deeper systemic oxidative support within their longevity protocol, often combined with NAD+ IV therapy and biomarker tracking.