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Liondale Medical

New York City, United States of America 7 treatments

About

Liondale Medical is a boutique integrative and regenerative medicine practice located at 10 West 74th Street, Suite 1E, on Manhattan's Upper West Side — a practice Dr. Lionel Bissoon D.O. has operated for over 20 years. The clinic limits itself to a maximum of 10 patients per day, and initial consultations run two hours, reflecting a depth-first philosophy uncommon in New York City's longevity market. Dr. Bissoon specializes in anti-aging, regenerative, and integrative medicine, bioidentical hormone replacement therapy, men's health, ozone therapy, and IV and NAD+ infusions. The treatment menu is among the most advanced available in NYC: medical ozone therapy includes the hyperbaric 10-pass protocol and EBO2 (extracorporeal blood oxygenation and ozonation with hemealumination), which Liondale claims to be among the first to offer in New York City. Therapeutic plasma exchange (TPE) — a procedure where blood plasma is removed via apheresis and replaced with fresh albumin — is offered at $8,000–$10,000+ per session as a premium longevity intervention, with evidence from a 2025 RCT showing measurable reductions in biological age. Comprehensive hormone testing covers sex hormones, thyroid, metabolic markers, cortisol, and lipid profiles, with bioidentical hormone replacement therapy (BHRT) protocols using pellets, topical gels, creams, patches, and oral formulations. Regenerative medicine services include PRP, stem cell, and exosome treatments for musculoskeletal injuries, hair restoration, and skin rejuvenation. NAD+ IV infusions are a core offering, paced slowly for tolerability. The clinic is open Monday through Thursday 9:30am–5:00pm and is closed Friday through Sunday.
Price range
$8,000.00
Treatments
7
Locations
1

Treatments

7 treatments

prp-prf

PRP Regenerative Medicine (Joints & Musculoskeletal)

Platelet-rich plasma (PRP) and regenerative medicine at Liondale Medical for musculoskeletal conditions including arthritis, rotator cuff injuries, tendonitis, and plantar fasciitis. Blood is drawn, centrifuged to concentrate platelets at 3–5 times normal levels, and injected at the target site. Stem cell treatments using bone marrow or adipose-derived stem cells, and exosome infusions from placental tissue, are also offered as standalone or combination regenerative protocols.

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ozone-therapy

EBO2 — Extracorporeal Blood Oxygenation and Ozonation

EBO2 (Extracorporeal Blood Oxygenation and Ozonation) at Liondale Medical combines an apheresis machine with hemealumination — simultaneous exposure of blood to UVA, UVC, red, green, and blue light wavelengths — while ozone is infused. Used for autoimmune conditions, chronic infections, systemic inflammation, and brain fog. A highly advanced ozone-adjacent blood purification protocol offered by Dr. Bissoon in Manhattan.

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prp-hair

PRP Hair Restoration

PRP scalp injections for hair restoration at Liondale Medical on Manhattan's Upper West Side, using concentrated platelet-rich plasma injected into the scalp to stimulate hair follicle activity and reduce hair thinning. Combined with stem cell and exosome treatments as needed. If hair loss is hormone-driven, BHRT and IV nutritional therapy are incorporated. Supervised by Dr. Lionel Bissoon D.O., who also manages the underlying hormonal and nutritional causes of hair loss.

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iv-therapy

Therapeutic Plasma Exchange (TPE)

Therapeutic plasma exchange (TPE) at Liondale Medical removes aging blood plasma via an apheresis machine and replaces it with fresh albumin solution — effectively diluting circulating inflammatory proteins, senescent factors, and accumulated metabolic byproducts. Industry pricing runs $8,000–$10,000+ per session. A 2025 randomized controlled trial found TPE reduced biological age by 1.32 years per session. Each session runs 2–3 hours under physician supervision at the Upper West Side clinic.

$8,000.00

hormone-testing

Comprehensive Hormone Testing & BHRT

Comprehensive hormone panel and bioidentical hormone replacement therapy (BHRT) at Liondale Medical, covering sex hormones (testosterone, estradiol, progesterone, DHEA-S), thyroid (TSH, free T3, free T4), metabolic markers (glucose, insulin, HbA1c), lipid panel, cortisol, and SHBG. Dr. Bissoon manages both men's health and menopause programs. BHRT options include pellets (5–6 month duration), topical gels, patches, and oral formulations. Follow-up labs at 6–8 weeks; semi-annual monitoring thereafter.

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ozone-therapy

Hyperbaric 10-Pass Medical Ozone Therapy

The hyperbaric 10-pass ozone protocol at Liondale Medical draws a volume of blood, mixes it with medical-grade ozone under pressure, and reinfuses it — repeating the cycle ten times in a single session. Dr. Lionel Bissoon D.O. uses this advanced protocol for anti-aging maintenance (monthly), and for individuals managing chronic fatigue, Lyme disease, or persistent infections (one to two sessions per week). Liondale claims to be among New York City's first practices to offer this technology.

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iv-therapy

NAD+ IV Infusion

Physician-guided NAD+ (nicotinamide adenine dinucleotide) IV infusion at Liondale Medical on Manhattan's Upper West Side. Infused slowly over 1.5–3 hours under Dr. Bissoon's supervision to support cellular energy production, mitochondrial function, and longevity pathways. NAD+ is a core offering at the practice, used alongside ozone therapy and hormone optimization programs.

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Locations

1 location

Frequently Asked Questions about Liondale Medical

Liondale Medical
7 treatments available