Type
IV Vitamin Therapy
Duration
3 hours
Therapeutic plasma exchange (TPE) at Liondale Medical removes aging blood plasma via an apheresis machine and replaces it with fresh albumin solution — effectively diluting circulating inflammatory proteins, senescent factors, and accumulated metabolic byproducts. Industry pricing runs $8,000–$10,000+ per session. A 2025 randomized controlled trial found TPE reduced biological age by 1.32 years per session. Each session runs 2–3 hours under physician supervision at the Upper West Side clinic.
About this treatment
Therapeutic plasma exchange (TPE) at Liondale Medical is one of the most clinically substantiated and technically complex longevity interventions currently available in private clinical practice in New York City. The procedure uses an apheresis machine — a device that separates blood components by centrifugation or membrane filtration — to continuously withdraw blood from the patient, remove the liquid plasma fraction, and return the cellular components…
Good to know
- Apheresis-based plasma removal and albumin replacement
- 2025 RCT: -1.32 biological years per session (TPE alone)
- $8,000–$10,000+ per session; initial series 3–6 sessions
- Pre/post biomarker tracking (CRP, IL-6, epigenetic markers)
About the clinic
Reviews, team and credentials
Independent review links and clinic-reported team information.
41 clinic reviews
From independent platforms
Industry range $8,000–$10,000+ per session; Liondale-specific pricing discussed at consultation. Initial series of 3–6 sessions recommended, then monthly or quarterly maintenance. Requires certified apheresis nurse and physician supervision.