Comprehensive Hormone Testing & BHRT

Comprehensive hormone panel and bioidentical hormone replacement therapy (BHRT) at Liondale Medical, covering sex hormones (testosterone, estradiol, progesterone, DHEA-S), thyroid (TSH, free T3, free T4), metabolic markers (glucose, insulin, HbA1c), lipid panel, cortisol, and SHBG. Dr. Bissoon manages both men's health and menopause programs. BHRT options include pellets (5–6 month duration), topical gels, patches, and oral formulations. Follow-up labs at 6–8 weeks; semi-annual monitoring thereafter.

Hormone testing and bioidentical hormone replacement therapy at Liondale Medical is conducted under the direct supervision of Dr. Lionel Bissoon D.O., who has specialized in this area for over two decades on Manhattan's Upper West Side. The evaluation begins with a comprehensive hormone panel designed to characterize the patient's complete hormonal status across multiple axes: the gonadal axis (total testosterone, free testosterone, estradiol, progesterone, DHEA-S, sex hormone-binding globulin), the thyroid axis (TSH, free T3, free T4), the adrenal stress axis (cortisol pattern through the day), and metabolic health indicators (fasting glucose, insulin, HbA1c for insulin resistance assessment, and a full lipid panel). This multi-axis approach reflects the integrative medicine perspective that hormonal health cannot be assessed in isolation — thyroid dysfunction affects sex hormone metabolism, insulin resistance disrupts SHBG and therefore free testosterone availability, and adrenal cortisol output interacts with both reproductive and thyroid hormone function. Dr. Bissoon manages both a men's health program and a menopause program using this same framework, individualized to patient sex, age, symptoms, and lab findings. Following an initial evaluation and the establishment of baseline hormone levels, BHRT is initiated if clinically appropriate. Delivery options offered at the clinic include testosterone pellets implanted subcutaneously with 5–6 month duration, topical testosterone gels and creams for daily application, transdermal patches, and oral formulations for appropriate hormones. HCG therapy and Clomid (used off-label in men for endogenous testosterone stimulation) are also available as part of the men's health program. Follow-up laboratory assessment at 6–8 weeks after initiation allows dose titration based on measured hormone levels and symptom response. Semi-annual monitoring is the standard cadence for established patients on BHRT programs. The clinic notes that many of its programs are at least partly self-pay given the comprehensive and often non-standard nature of the work relative to insurance coverage norms.