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DENIFE (Centrum estetické medicíny MUDr. Hana Plachá)

Karlovy Vary, Czechia 19 treatments

About

DENIFE is a physician-led aesthetic medicine and laser centre founded in 2003 by MUDr. Hana Plachá, located inside Alžbětiny lázně (Elizabeth's Spa), a landmark spa building in central Karlovy Vary, western Bohemia. The clinic combines injectable treatments — botulinum toxin for expression lines and excessive sweating, hyaluronic acid fillers for deep wrinkles, lips, neck and the backs of the hands, and mesotherapy biorevitalisation — with thread (mezonitě) lifts, laser work and device-based facials. Lasers include a fractional CO2 system for resurfacing and growth removal and a Velure S vascular laser for broken capillaries and spider veins. Device facials use Synergy radiofrequency, Hydrafacial, ultrasonic cleansing, an Elaxen PLLA collagen-stimulating mask, an Omnilux Contour FACE LED mask and the ICOONE body system. MUDr. Plachá graduated from Charles University Faculty of Medicine in Pilsen in 1991, is certified in both ophthalmology and plastic surgery with more than twenty years of eyelid surgery experience, lectures internationally and trains physicians in botulinum toxin, hyaluronic acid and mesotherapy. She is supported by chief nurse Lenka Smutná and clinician Monika Rolencová, who perform chemical peels and instrumented facials. The clinic holds a 5.0 out of 5 rating from 14 reviews on Estheticon with 100% of reviewers recommending it. Open Monday to Friday, 10:00–16:00.
Price range
Kč 1,000–Kč 10,000
Treatments
19
Locations
1
Languages
3

Treatments

19 treatments

skin-tightening

ICOONE Body Treatment (Cellulite & Contouring)

A non-invasive body treatment using the ICOONE device, whose patented roller handpieces apply micro-stimulation across the skin and underlying tissue to target cellulite, improve body contour and firm the skin. The multi-microalveolar action gently mobilises fat cells and the tissue matrix without injections or downtime, and is gentle enough to use over veins. At DENIFE it is offered as a comfortable, massage-like body treatment best done as a course.

Kč 1,500

laser

Fractional CO2 Laser Resurfacing

Fractional CO2 laser resurfacing that improves fine lines, scars, enlarged pores and pigmentation while stimulating new collagen. The laser delivers a controlled grid of micro-columns of energy that ablate the top layer of skin and trigger a renewing peel, so smoother, firmer skin regenerates underneath. At DENIFE the treatment is used on the face, neck, décolleté and hands and is performed under medical supervision by the clinic's team.

Kč 4,500

botox-fillers

Anti-Wrinkle Injections (Botulinum Toxin)

Botulinum toxin treatment that softens the dynamic expression lines of the upper face — the vertical frown lines between the brows (glabella), the horizontal forehead lines and the crow's feet at the corners of the eyes. Tiny doses temporarily relax the small mimic muscles so the skin above them creases less when you frown, squint or raise your brows. At DENIFE the injections are placed with a very fine needle under local anaesthesia by MUDr. Hana Plachá, who trains other physicians in botulinum toxin application, aiming for a refreshed rather than frozen look.

Kč 3,000
3% below Karlovy Vary avg

skin-tightening

Synergy+ Radiofrequency Facial

A non-invasive multi-phase device facial using the Synergy+ system to refresh skin tone, texture and firmness. The treatment combines a deep cleanse with oxygen, radiofrequency energy to restore collagen and elastin, and ultrasonic infusion of serums into the skin. At DENIFE it is offered as a comfortable, no-downtime facial suitable for all ages, addressing fine lines and uneven texture in a single visit.

Kč 2,000

chemical-peels

Ultrasonic Skin Cleansing

A gentle deep-cleansing facial that uses an ultrasonic spatula to lift away dead skin cells, excess oil and impurities without the trauma of aggressive mechanical extraction. High-frequency vibrations loosen debris from the pores while serums or a mask suited to your skin type are worked in. At DENIFE this is a comfortable, no-downtime facial that leaves the skin cleaner, smoother and better able to absorb skincare.

Kč 1,200

botox-fillers

Hand Rejuvenation (Hyaluronic Acid)

A filler treatment that restores volume to the backs of the hands, where ageing thins the skin and makes tendons, veins and bones more prominent. Soft hyaluronic acid gel is placed under the skin to plump the area, soften the bony, hollow look and improve skin quality so the hands better match a rejuvenated face. At DENIFE the treatment is performed by MUDr. Hana Plachá using the same precise needle-or-cannula technique and local anaesthesia as for facial fillers.

Kč 6,000

thread-lift

3D Mesothread Face Lift (Lifting Without a Scalpel)

A non-surgical face lift using 3D mesothreads to reposition and support sagging facial tissue without a scalpel. The threads create a supportive mesh under the skin and stimulate collagen, producing a visible lift — often noticeable by the second day — and they can be combined with fillers for fuller rejuvenation. At DENIFE this is performed by MUDr. Hana Plachá and suits more significant tissue laxity, such as after weight loss.

Kč 3,000
Cheapest in Karlovy Vary

skin-tightening

Omnilux LED Light Therapy Mask

LED light therapy using the Omnilux Contour FACE mask, which delivers near-infrared (830 nm) and red (633 nm) light to stimulate skin-cell metabolism, support healing and boost collagen — a gentle 'light lifting' for skin rejuvenation and acne-prone skin. The light penetrates to around 3 mm and triggers the skin's own repair processes without heat or downtime. At DENIFE the session follows a cleanse and lasts around 15–20 minutes, with an optional hydrogel mask add-on.

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mesotherapy

Mesotherapy & Biorevitalisation

Mesotherapy is a skin-revitalising treatment that delivers a cocktail of hyaluronic acid, vitamins and amino acids directly into the skin through a series of micro-injections. Rather than adding volume like a filler, it hydrates the skin from within, improves firmness and elasticity and softens fine lines. At DENIFE it is used on the face, neck, décolleté and the backs of the hands, applied through tiny punctures or a very fine cannula under local anaesthesia by MUDr. Hana Plachá, who trains physicians in the technique.

Kč 2,000

chemical-peels

Hydrafacial

Hydrafacial is a multi-step device facial that cleanses, gently exfoliates and resurfaces the skin while infusing it with hydrating and nourishing serums. Using a patented Vortex-Fusion tip, it combines a deep cleanse, a mild chemical peel and the delivery of actives into the skin in one comfortable session with no downtime. At DENIFE it is offered as an overall rejuvenating facial that leaves skin clearer, smoother and more hydrated straight away.

Kč 2,000

skin-tightening

Elaxen PLLA Mask with Ultrasonic Cleansing

A collagen-boosting facial that pairs ultrasonic deep cleansing with the Elaxen mask, which contains poly-L-lactic acid (PLLA) to stimulate the skin's own collagen, plus niacinamide (vitamin B3) to hydrate, calm redness and help with acne-prone skin. The session finishes with an oxygen-and-peptide fluid for an extra boost. At DENIFE it is offered as a comfortable, no-downtime treatment suitable for all skin types, including rosacea-prone skin.

Kč 2,000

botox-fillers

Neck Rejuvenation (Hyaluronic Acid)

A hyaluronic acid treatment for the neck, where thin, crepey skin and horizontal 'necklace' lines reveal age. Rather than dramatic volumising, this is a biorevitalising filler treatment that hydrates the neck skin, improves its quality and softens fine horizontal lines. At DENIFE the hyaluronic acid is introduced under local anaesthesia by MUDr. Hana Plachá, who also treats the neck as part of broader facial rejuvenation.

Kč 6,000

thread-lift

Chin & Jawline Lift with Meso-Threads

A non-surgical lift for a sagging chin and jawline using meso-threads — fine cosmetic-therapeutic threads inserted into the deeper layers of the skin through hollow needles. The threads stimulate the skin's own collagen and tighten loose contours, giving a result comparable to a surgical lift but without incisions or scarring. At DENIFE the threads are placed under numbing cream or local anaesthesia by MUDr. Hana Plachá, with minimal downtime.

Kč 3,000
Cheapest in Karlovy Vary

laser

CO2 Laser Removal of Skin Growths & Moles

Precise removal of benign skin growths — fibromas, moles and other small lesions — using a CO2 laser. The focused laser beam vaporises the growth with minimal bleeding and supports faster, cleaner healing than some traditional methods. At DENIFE a mandatory dermatological evaluation is carried out before any growth is removed, so that only lesions confirmed as benign are treated.

Kč 1,000
2% below Karlovy Vary avg

botox-fillers

Lip Fillers (Hyaluronic Acid)

Lip enhancement using soft hyaluronic acid gel to add volume, improve definition and balance the shape of the lips, or to restore lips that have thinned with age. At DENIFE the filler is placed through a single puncture with a needle or cannula under local anaesthesia by MUDr. Hana Plachá, with a visible result straight away and the option to dissolve the filler if an adjustment is ever wanted.

Kč 6,000

laser

Vascular Laser (Velure S) for Capillaries & Spider Veins

Laser treatment with the Velure S system to close off unwanted blood vessels in the skin — broken capillaries on the cheeks and nose, small spider veins and hemangiomas. The laser beam is absorbed by the blood in the targeted vessel, heating and sealing it so it fades from view, while sparing the surrounding skin. At DENIFE the Velure S vascular laser is used by the clinic's team to improve facial redness and visible vessels.

Kč 1,000
2% below Karlovy Vary avg

botox-fillers

Deep Wrinkle Fillers (Hyaluronic Acid)

Hyaluronic acid dermal filler used to soften deep folds and restore volume in the cheeks and the nasolabial folds (the lines running from the nose to the corners of the mouth). A soft gel based on hyaluronic acid is placed beneath the skin to lift and smooth the treated area, with a visible result straight away. At DENIFE the filler is placed with a needle or a cannula through a single puncture under local anaesthesia by MUDr. Hana Plachá, an experienced plastic surgeon.

Kč 6,000

botox-fillers

Excessive Sweating Treatment (Botulinum Toxin)

An injectable treatment for excessive sweating (hyperhidrosis) that uses botulinum toxin to temporarily switch off the overactive sweat glands in a treated area. It is most commonly used for the armpits, but the palms and soles can also be treated. At DENIFE the toxin is delivered through a fine needle under local anaesthesia by MUDr. Hana Plachá in a quick, almost painless session, giving relief from sweating and the staining and odour that come with it for several months at a time.

Kč 10,000

chemical-peels

Retinol (Chemical) Peel

A retinol-based chemical peel that resurfaces the skin to soften fine lines and wrinkles, improve the signs of acne, fade pigmentation and even out skin tone, while firming the skin. Retinol (a vitamin-A derivative) speeds cell turnover and stimulates renewal, so a controlled peeling reveals fresher skin underneath. At DENIFE the peel is applied by the clinic's trained team and is offered for the face, or the face and neck together.

Kč 2,000

Locations

1 location

What clients say

{"quote":"Satisfied with the approach, the procedure and the result — Botox, upper-lip filler and nasolabial folds.","author":"Hanka73","source":"Estheticon"}

{"quote":"Everything was fine. The nurse and the doctor are both very nice!","author":"Adela P.","source":"Estheticon"}

{"quote":"I'm completely satisfied with everything — cellulite treatment, Botox and lip augmentation.","author":"Verified patient","source":"Estheticon"}

Frequently Asked Questions about DENIFE (Centrum estetické medicíny MUDr. Hana Plachá)

DENIFE (Centrum estetické medicíny MUDr. Hana Plachá)
19 treatments available