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DENIFE clinic interior, Alžbětiny lázně, Karlovy Vary
Consultation room at DENIFE
Treatment room at DENIFE

Anti-Wrinkle Injections (Botulinum Toxin)

Type

Botox & Fillers

Duration

20 min

Botulinum toxin treatment that softens the dynamic expression lines of the upper face — the vertical frown lines between the brows (glabella), the horizontal forehead lines and the crow's feet at the corners of the eyes. Tiny doses temporarily relax the small mimic muscles so the skin above them creases less when you frown, squint or raise your brows. At DENIFE the injections are placed with a very fine needle under local anaesthesia by MUDr. Hana Plachá, who trains other physicians in botulinum toxin application, aiming for a refreshed rather than frozen look.

Anti-wrinkle injections use small, precisely placed doses of botulinum toxin to temporarily reduce the activity of the facial mimic muscles. When those muscles contract less forcefully, the overlying skin folds less, and the dynamic lines etched over years of repeated expression gradually soften over the days that follow. The treatment is most commonly used across the upper third of the face — the glabellar frown line, the forehead and the crow's feet — either individually or in combination for a balanced result. At DENIFE in Karlovy Vary the session begins with a consultation in which MUDr. Hana Plachá assesses how your face moves at rest and in animation and agrees which areas to treat. A very thin needle is used and local anaesthesia is applied for comfort, so the injections themselves take only a few minutes. Most people return to normal activities the same day while avoiding heat, lying flat and vigorous exercise for the rest of the day. The effect is not immediate: onset is typically two to three days, the full result settles around day 15, and softened expression then lasts roughly three to nine months before muscle movement gradually returns and the treatment can be repeated. Because MUDr. Plachá is certified in plastic surgery and lectures internationally on botulinum toxin, dosing and placement are tailored to your individual anatomy. She reviews your suitability and any reasons to avoid treatment — such as pregnancy or breastfeeding — before proceeding. The treatment suits adults who want to soften upper-face expression lines while keeping natural movement.

Key Details

Areas
Frown line, forehead, crow's feet
Onset
2–3 days; full effect ~day 15
Duration
3–9 months
Performed by
MUDr. Hana Plachá

Who Is This For?

Adults wanting to soften dynamic upper-face wrinkles while keeping a natural look

What's Included

Consultation and assessment of facial movement
Local anaesthesia for comfort
Botulinum toxin application with a very fine needle to the agreed area(s)

Preparation Required

Avoid blood-thinning medication and alcohol before treatment where possible. After treatment, avoid heat, lying flat and vigorous exercise for the rest of the day.

Compare Botox & Fillers in Czechia →
Price
Kč 3,000

3,000–9,000 Kč per treatment, depending on how many areas are treated (frown line, forehead, crow's feet) and the number of units used. The final price is agreed at consultation; from 3,000 Kč for a single area.

3% below Karlovy Vary avg
Category
Skin Treatments
Duration
20 min
DENIFE (Centrum estetické medicíny MUDr. Hana Plachá)

DENIFE (Centrum estetické medicíny MUDr. Hana Plachá)

Physician-led aesthetic medicine and laser centre inside the historic Elizabeth's Spa in central Karlovy Vary, offering botulinum toxin, hyaluronic acid fillers, mesotherapy, thread lifts, laser and device-based facial and body treatments.

Client Review

"{"quote":"Satisfied with the approach, the procedure and the result — Botox, upper-lip filler and nasolabial..."

Kč 3,000