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DENIFE clinic interior, Alžbětiny lázně, Karlovy Vary
Consultation room at DENIFE
Treatment room at DENIFE

Anti-Wrinkle Injections (Botulinum Toxin)

Type

Botox & Fillers

Duration

20 min

What's included

3 deliverables in this treatment

  • Consultation and assessment of facial movement
  • Local anaesthesia for comfort
  • Botulinum toxin application with a very fine needle to the agreed area(s)

Botulinum toxin treatment that softens the dynamic expression lines of the upper face — the vertical frown lines between the brows (glabella), the horizontal forehead lines and the crow's feet at the corners of the eyes. Tiny doses temporarily relax the small mimic muscles so the skin above them creases less when you frown, squint or raise your brows. At DENIFE the injections are placed with a very fine needle under local anaesthesia by MUDr. Hana Plachá, who trains other physicians in botulinum toxin application, aiming for a refreshed rather than frozen look.

About this treatment

Anti-wrinkle injections use small, precisely placed doses of botulinum toxin to temporarily reduce the activity of the facial mimic muscles. When those muscles contract less forcefully, the overlying skin folds less, and the dynamic lines etched over years of repeated expression gradually soften over the days that follow. The treatment is most commonly used across the upper third of the face — the glabellar frown line, the forehead and the crow's feet —…

At DENIFE in Karlovy Vary the session begins with a consultation in which MUDr. Hana Plachá assesses how your face moves at rest and in animation and agrees which areas to treat. A very thin needle is used and local anaesthesia is applied for comfort, so the injections themselves take only a few minutes. Most people return to normal activities the same day while avoiding heat, lying flat and vigorous exercise for the rest of the day. The effect is not…

Good to know

Areas
Frown line, forehead, crow's feet
Onset
2–3 days; full effect ~day 15
Duration
3–9 months
Performed by
MUDr. Hana Plachá

Who is this for?

Adults wanting to soften dynamic upper-face wrinkles while keeping a natural look

Preparation required

Avoid blood-thinning medication and alcohol before treatment where possible. After treatment, avoid heat, lying flat and vigorous exercise for the rest of the day.

About the clinic

Reviews, team and credentials

Independent review links and clinic-reported team information.

5.0

14 clinic reviews

From independent platforms

Clinical team

Founded and led by MUDr. Hana Plachá, who graduated from the Charles University Faculty of Medicine in Pilsen in 1991 and is certified in both ophthalmology and plastic surgery, with more than twenty years of eyelid-surgery experience. She is a member of the Czech Medical Association of J. E. Purkyně (ČLS JEP), has completed international internships in Princeton, France, Italy, Switzerland, Germany and London, and…

Languages: Czech, English, German

What clients say

"{"quote":"Satisfied with the approach, the procedure and the result — Botox, upper-lip filler and nasolabial folds.","author":"Hanka73","source":"Estheticon"}"

"{"quote":"Everything was fine. The nurse and the doctor are both very nice!","author":"Adela P.","source":"Estheticon"}"

View the full DENIFE (Centrum estetické medicíny MUDr. Hana Plachá) profile
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