Longevity.haus
DENIFE clinic interior, Alžbětiny lázně, Karlovy Vary
Consultation room at DENIFE
Treatment room at DENIFE

Deep Wrinkle Fillers (Hyaluronic Acid)

Type

Botox & Fillers

Duration

45 min

What's included

3 deliverables in this treatment

  • Consultation and treatment planning
  • Local anaesthesia for comfort
  • Hyaluronic acid filler placement via a single puncture with needle or cannula

Hyaluronic acid dermal filler used to soften deep folds and restore volume in the cheeks and the nasolabial folds (the lines running from the nose to the corners of the mouth). A soft gel based on hyaluronic acid is placed beneath the skin to lift and smooth the treated area, with a visible result straight away. At DENIFE the filler is placed with a needle or a cannula through a single puncture under local anaesthesia by MUDr. Hana Plachá, an experienced plastic surgeon.

About this treatment

Dermal fillers based on hyaluronic acid replace volume that the face loses with age and soften deep static lines that remain visible even at rest. Hyaluronic acid is a substance found naturally in the skin that binds water and supports the tissue; in soft gel form it can be placed precisely to lift a hollow cheek, support a deep nasolabial fold or smooth an established wrinkle, restoring a more youthful contour.

At DENIFE in Karlovy Vary the treatment begins with a consultation in which MUDr. Hana Plachá assesses the face and agrees a plan — often supporting a neighbouring structure such as the cheek gives a more natural result than treating a line directly. Local anaesthesia is applied and the gel is introduced through a single entry point using a fine needle or a blunt cannula, then shaped by hand. The result is visible immediately and continues to settle over…

Good to know

Areas
Cheeks, nasolabial folds, deep wrinkles
Result
Immediate; settles in 1–3 days
Duration
6–12 months
Adjustable
Yes — hyaluronic acid can be dissolved

Who is this for?

Adults wanting to restore facial volume and soften deep static folds

Preparation required

Avoid blood-thinning medication and alcohol beforehand to reduce bruising. Avoid heat, saunas and heavy exercise for 24–48 hours after treatment.

About the clinic

Reviews, team and credentials

Independent review links and clinic-reported team information.

5.0

14 clinic reviews

From independent platforms

Clinical team

Founded and led by MUDr. Hana Plachá, who graduated from the Charles University Faculty of Medicine in Pilsen in 1991 and is certified in both ophthalmology and plastic surgery, with more than twenty years of eyelid-surgery experience. She is a member of the Czech Medical Association of J. E. Purkyně (ČLS JEP), has completed international internships in Princeton, France, Italy, Switzerland, Germany and London, and…

Languages: Czech, English, German

What clients say

"{"quote":"Satisfied with the approach, the procedure and the result — Botox, upper-lip filler and nasolabial folds.","author":"Hanka73","source":"Estheticon"}"

"{"quote":"Everything was fine. The nurse and the doctor are both very nice!","author":"Adela P.","source":"Estheticon"}"

View the full DENIFE (Centrum estetické medicíny MUDr. Hana Plachá) profile
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