10 Best Botox & Fillers Clinics in Prague (2026)
We ranked the top 10 of 42 botox & fillers clinics in Prague by patient reviews, pricing, and international patient services. Prices from Kč 2,500 to Kč 8,500.
Clinics
42
Avg Rating
4.9/5
From
Kč 2,500
Top Rated
Artmedica Clinic
Best Value
Laser Esthetic
Botox & Fillers Clinics
Artmedica Clinic
Žatecká 55/14, Staré Město (Josefov), Praha 1, 110 00, Czech Republic
Artmedica Clinic is a private aesthetic medicine practice in the heart of Prague's Staré Město (Old Town), founded and led by MUDr. Kateřina Adamcová — an ENT surgeon from Charles University's 3rd Medical Faculty who holds international certification in aesthetic and anti-aging medicine and is one of only three APTOS thread-lift trainers in the entire Czech Republic. The clinic operates the Alma Harmony multi-platform laser system (ClearLift, ClearSkin, Dye-VL and Bio-Boost modules) and the Candela GentleLASE alexandrite laser with dual dynamic cooling, covering permanent hair removal, skin rejuvenation, pigmentation and vascular lesion treatment. Injectable services include Allergan botulinum toxin for wrinkles and hyperhidrosis, premium hyaluronic-acid fillers, Profhilo bioremodeling, polynucleotide biostimulation (PDRN), Xela Rederm Swiss redermalization — which Artmedica introduced to Czech Republic as the first clinic — and PRP plasma therapy. Body contouring is handled with LESC cold-ultrasonic liposuction under local anaesthesia only, and injectable lipolysis. The multidisciplinary team includes MUDr. Alena Stumpfová (board-certified dermatovenerologist), head nurse Marcela Štěpánková (50+ years' specialist experience in laser hair removal and Dermapen), and nurse Petra Pavlíková with ICU and cosmetology background. The clinic holds accreditation from the Czech Medical Chamber, IMCAS Academy, AMWC and the Allergan Medical Institute. On Reservio the clinic carries a perfect 5.0 / 5.0 score across 75 verified reviews.
Available Botox & Fillers:
Botulinum toxin injections administered by physician to temporarily relax facial muscles driving expression lines — forehead, frown lines between the brows, crow's feet, nasal root, neck platysma, jaw masseter (bruxism), drooping mouth corners and smoker's lines. The injection session takes around 10 minutes; fine needles make the procedure nearly painless. Results last three to six months and with repeat treatments wrinkles gradually diminish as muscles are trained to contract less forcefully. Artmedica Clinic also offers botulinum toxin for hyperhidrosis (excessive sweating of underarms, palms and soles) and migraine prevention.
Hyaluronic acid filler injections by physician for volume restoration, lip augmentation, nasolabial fold smoothing, under-eye hollow correction, non-surgical nose reshaping, jawline and chin definition, and cheekbone enhancement. A thin needle or blunt cannula delivers the cross-linked gel precisely into the target tissue layer. Results are immediate and develop fully at 21 days; duration is six to eighteen months depending on the area and product density. Artmedica Clinic offers hyaluronidase dissolution if correction is needed.
Eternal Clinic
Chlumčanského 497/5, 180 00 Praha 8 - Libeň (Bulovka Business & Medical Centre)
Eternal Clinic is a premium aesthetic medicine center in Prague led by two experienced surgeons from Motol University Hospital - MUDr. Patrik Palenčár and MUDr. Alena Mušálková. They combine years of surgical expertise with modern aesthetic procedures for natural, long-lasting results. Services include comprehensive hair loss treatment, hair transplantation, skin rejuvenation, botulinum toxin, dermal fillers, and blepharoplasty. Installment payment plans available.
Available Botox & Fillers:
Anti-wrinkle injection treatment for one facial area (forehead, glabella, or crow's feet).
Comprehensive anti-wrinkle treatment for forehead, frown lines, and crow's feet.
Complete facial anti-wrinkle treatment covering all dynamic wrinkle areas.
Follow Clinic
Sinkulova 38/2, 147 00 Praha 4-Podolí, Czech Republic
Follow Clinic is an aesthetic medicine and cosmetic clinic located at Sinkulova 38/2 in the upscale Prague 4-Podolí neighbourhood, steps from the Vltava riverbank. The clinic was founded on a philosophy of individualized care and natural results — a direct response to the founders' own negative experiences at impersonal aesthetic clinics. Every treatment plan is tailored to the individual client rather than applying a one-size approach. The medical team includes dermatologist MUDr. Nikola Lochmanová, Dr. Nicole Kufelová (aesthetic medicine, lip filler specialist), Dr. Hana Brázdová (anti-aging medicine and certified Karisma biostimulant trainer for the Italian brand), Dr. Anna Zborovská (botulinum toxin), and founder Ivona Jarolímová (plasma pen specialist). Injectable treatments use premium products including Stylage (French HA with antioxidants), Juvéderm, Profhilo (97% HA bioremodeling), Radiesse, and Aptos threads. Cosmetic facial treatments are delivered with Dermapen for microneedling combined with Hyalual chemical peels, biorevitalization, exosomes, and the premium Nanoderm and DUBAJ Blue Elixir protocols. Luxury MEDISPA facials are offered using Orveda — a globally recognized pure vegan skincare brand. The clinic is open Monday–Friday 09:00–18:00 by appointment, with online booking via the Alteg platform. Reviews on Firmy.cz rate the clinic 100 out of 100, with clients highlighting the warm, attentive care and high-quality results from treatments such as dermapen.
Available Botox & Fillers:
Volume modelling at Follow Clinic uses hyaluronic acid fillers (Stylage and Juvéderm) to restore midface volume, define the jawline, lift the temples, and reduce nasolabial folds. Pricing is straightforward: 8,500 Kč per ml, with multi-ml packages at 15,000 Kč (2 ml) and 21,000 Kč (3 ml) — covering cheeks, chin, temples, jawline, or nasolabial folds in a single session. This is a doctor-administered procedure for clients experiencing facial volume loss or wanting structural facial enhancement without surgery. Duration of effect is 12–24 months depending on area and product used.
Botulinum toxin (Botox) treatment for forehead lines, glabellar frown lines, and crow's feet at Follow Clinic Prague, administered by a qualified aesthetic doctor. The full upper face combination — all three zones — is priced at 8,500 Kč, with each individual zone available from 3,500 Kč. Baby Botox micro-doses are offered for clients seeking subtle softening rather than full relaxation. Results develop over 5–14 days and typically last 3–6 months. A complimentary touch-up is included at the 10–14 day review.
Beyond the standard upper face zones, Follow Clinic's doctors offer botulinum toxin for specialised indications: the Nefertiti neck lift (9,500 Kč) tightens the lower face and neck by releasing platysmal bands; masseter injections (7,200 Kč) slim a square jaw and relieve bruxism; and targeted applications address gummy smile, lip flip, drooping mouth corners, chin texture, and nose wrinkles. The full face + Nefertiti package (16,000 Kč) offers the most comprehensive rejuvenation in a single session. All treatments are performed by a qualified aesthetic doctor at the Prague 4-Podolí clinic, and a complimentary touch-up is included at 10–14 days.
RAJSKA Clinic
Lighthouse Building B, Jankovcova 1566/2B, Praha 7 – Holešovice, 170 00, Czech Republic
RAJSKA Clinic is a private aesthetic dermatology practice located in Lighthouse Building B in Praha 7 – Holešovice, founded and led by MUDr. Lucie Rajská, Ph.D., who holds a medical degree from Masaryk University (2010) and a doctorate from Charles University's 2nd Faculty of Medicine (2017), with prior clinical experience at Na Bulovce Hospital and specialised certifications in anti-aging medicine. The clinic operates without any health insurance contracts — every treatment is private — which allows it to maintain appointment depth and individualised care over throughput. Seven physicians cover the full spectrum from general and paediatric dermatology to advanced injectable aesthetics and surgical mole removal, making RAJSKA unusual among aesthetic practices in being able to handle clinical skin conditions alongside cosmetic procedures in a single visit. Equipment highlights include the VIVACE microneedle radiofrequency system for deep collagen and elastin remodelling, the ALMA PIXEL CO2 fractional laser for both superficial rejuvenation and deep resurfacing, and the ADENA LCD G+ IPL platform for vascular and pigmentation concerns. Injectable offerings span botulinum toxin (Bocouture, Baby Botox, full-face protocol), hyaluronic acid fillers, Radiesse calcium hydroxyapatite lifting, Profhilo and Structura bioremodelling, Jalupro biorevitalisation, and Aptos thread lifting with multiple thread types. The clinic openly claims a 5/5 Google rating with 14-plus named testimonials displayed on the homepage, praising the team's precision, warmth, and commitment to natural outcomes. Appointments typically require at least two weeks' advance booking, and the clinic's philosophy — "aesthetics without exaggeration, naturalness without compromise" — is reinforced through its choice not to accept walk-ins or insurance-driven time pressures.
Available Botox & Fillers:
Hyaluronic acid dermal fillers at RAJSKA Clinic restore facial volume, define lips, soften under-eye hollows, and contour facial structures using premium HA products — applied by physicians who treat natural harmony as a non-negotiable outcome. The clinic's philosophy explicitly rejects the overdone look: volumes are calibrated to the individual's facial anatomy, not trend-driven targets. Lips, under-eye tear troughs, cheekbones, nasolabial folds, and jawline definition are all available in a single consultation-and-treatment appointment, with topical anaesthetic applied to ensure comfort during injection.
Radiesse calcium hydroxyapatite filler at RAJSKA Clinic provides immediate lifting with long-term biostimulation — distinct from standard HA fillers, which add volume but do not stimulate new tissue. Radiesse microspheres create a physical scaffold that supports the overlying skin while triggering the body's own collagen-forming cells to produce new structural matrix. Applied to the face, neck, décolletage, or hands, Radiesse achieves a lifting effect without adding puffiness, making it particularly suited to patients who want tightening and firmness rather than volume. A single session typically delivers results lasting twelve to eighteen months.
Polylactic acid (PLLA) biostimulation at RAJSKA Clinic uses Lenisna and Juvelook — injectable solutions that gradually rebuild collagen over three to six months, delivering the most natural and durable rejuvenation of all injectable options. Unlike HA fillers that produce instant visible volume, PLLA works invisibly for the first few weeks and then delivers a gradual, natural-looking improvement as new collagen integrates into the skin's matrix. Treatments cover the face, neck, décolletage, and hands; Juvelook's polynucleotide formula targets the delicate eye area specifically. Results are expected to last eighteen to twenty-four months from a full three-session course.
Aether Clinic
Národní 135/14, 1st floor, building DRN, 110 00 Praha 1, Czech Republic
Aether Aesthetic and Beauty Clinic offers more than 300 services in aesthetic medicine, dermatology, body contouring, and spa wellness. Features 15+ premium lasers and exclusive treatments available only at this clinic in Czech Republic.
Available Botox & Fillers:
Premium hyaluronic acid filler for facial volumization and contouring.
Calcium-based collagen stimulator for facial lifting and volumization.
Exclusive biologically derived collagen product for skin regeneration (only available in Czech Republic at this clinic).
Be Elite Clinic
Jindřišská 20, 110 00 Praha 1, Czech Republic
Be Elite Clinic is a private aesthetic medicine and plastic surgery center in the heart of Prague led by MUDr. Monika Kavková, an internationally certified expert with APTOS certification. They combine classic Western medicine with unique Eastern methods for non-invasive lifting.
Available Botox & Fillers:
Botulinum toxin treatment for eye wrinkles.
Complete upper face treatment including forehead, glabella, and crow's feet.
Hyaluronic acid lip enhancement for volume and definition.
FaceExpert
FaceExpert, Maiselova 19, 110 00 Praha 1 – Josefov, Czech Republic
FaceExpert (Klinika estetické medicíny Praha) is a boutique aesthetic medicine practice located at Maiselova 19 in Josefov, the historic Jewish Quarter of central Prague 1. The clinic was founded by MUDr. Zuzana Macko, an aesthetic dermatologist and internationally recognised trainer who is certified by TEOXANE, Merz Aesthetics, and the MINT thread lifting system. She sits on the boards of SELM, IMCAS Academy, CAM Aesthetics, AMWC Academy, AMS, and the Czech Academy of Dermatovenereology — an unusually broad set of accreditations for a single-founder clinic. The team includes MUDr. Kateřina Besperát for aesthetic medicine and laser treatments, and MUDr. Alexandra Reptišová who specialises in non-invasive rhinoplasty and holds an additional qualification from Turkey. The clinical space is finished in a French-inspired boutique interior with artwork and a luxury atmosphere that sets it apart from the majority of Prague's medical aesthetic providers. The service catalogue covers the full non-surgical facial rejuvenation spectrum: botulinum toxin across 14 distinct areas, hyaluronic acid fillers, PDO/PLLA thread lifting, Ultraformer III HIFU, Morpheus 8 RF microneedling, Lumecca IPL, HydraFacial with LightStim LED, medical microneedling, chemical peels, biostimulation with Radiesse and Sculptra, PRP plasma therapy, polynucleotide injections, and diode laser hair removal. The clinic maintains a 4.9/5 rating from 51 verified reviews on Estheticon.cz with a 98% recommendation rate, and also runs the Dr. Macko Academy for physician education and an in-house SkinCeuticals product e-shop.
Available Botox & Fillers:
Botulinum toxin at FaceExpert is administered by MUDr. Zuzana Macko and her team using atraumatic needles for near-painless delivery. The treatment temporarily blocks neuromuscular transmission in targeted facial muscles, smoothing expression lines that form through repeated movement. Results appear within 3–14 days and last approximately 4–6 months. FaceExpert treats the full spectrum of areas: forehead, glabella, crow's feet, masseter (jaw slimming), Nefertiti lifting of the neck, gummy smile correction, underarm hyperhidrosis, palms, soles, and migraine treatment protocols. Combination-area pricing offers meaningful savings versus single-area rates. MUDr. Macko's international training credentials — including TEOXANE and Merz Aesthetics — ensure consistently refined outcomes, and the boutique Josefov setting makes this a sought-after destination for patients seeking an elevated treatment experience in central Prague.
Hyaluronic acid filler treatments at FaceExpert are performed by MUDr. Zuzana Macko and her team using premium HA products injected via fine needles or cannulas to restore volume, define contours, and hydrate the skin. Hyaluronic acid is a molecule naturally present in the body that binds water and maintains tissue fullness — when injected as a cross-linked gel, it provides durable volume and contouring that lasts 12–24 months depending on the area and product. FaceExpert treats the full facial map: lips, under-eye hollowing, cheekbone projection, chin definition, profile balance, liquid lifting, jawline contouring, temples, and hand rejuvenation. MUDr. Macko's international training credentials with TEOXANE and Merz Aesthetics — brands whose premium filler ranges she uses — underpin consistently natural-looking results. All procedures are carried out in the clinic's luxury French-inspired Josefov setting with a focus on comfort and subtlety.
Laser Esthetic
Washingtonova 17 (1st floor), 110 00 Praha 1 – Nové Město, Czech Republic
Laser Esthetic has operated from its Washingtonova 17 address in the heart of Prague's Nové Město district since 2000, steps from Wenceslas Square. The clinic is one of the Czech Republic's longest-running private aesthetic practices and holds official accreditation as a certified training facility of the Czech Medical Society JEP — the professional body that certifies physicians and nurses in laser and aesthetic dermatology nationwide. Its four-strong dermatology team (MUDr. Simona Bedřichová, MUDr. Ivana Úlehlová, MUDr. Květa Gazdíková, MUDr. Jan Říčař Ph.D.) works alongside four plastic surgeons and an anaesthesiologist. Laser equipment includes the Candela GentleLASE PRO alexandrite hair-removal laser with dynamic cooling, the Q-Plus Nd:YAG and Candela Alexandrite for pigmentation and tattoo removal, and the V-beam vascular dye laser for capillary and rosacea work — all USA-manufactured Candela systems. Non-laser services span botulinum toxin, hyaluronic acid fillers including the Redensity II under-eye protocol, PRP plasmalifting with RegenLab Cellular Matrix, Exilis dual-radiofrequency tightening, and microneedling. The clinic operates Monday–Thursday 09:00–17:30 and Friday 09:00–14:00 on a private-pay basis. On Estheticon, the Czech Republic's main patient-review platform for aesthetic clinics, Laser Esthetic holds 4.9 out of 5 from 47 verified reviews with a 98 % recommendation rate.
Available Botox & Fillers:
Precision botulinum toxin injections by Laser Esthetic's dermatologists to smooth dynamic forehead lines, frown lines and crow's feet by temporarily relaxing the underlying facial muscles. At 65 Kč per unit with clearly tiered area pricing, the clinic makes dosing transparent. Results develop gradually over ten days and last six to seven months, extending with repeated use. The same team also uses botulinum toxin to treat hyperhidrosis (excessive sweating).
Specialist under-eye hollow correction and dark circle treatment using Redensity II Eyes by Teoxane Switzerland — a purpose-formulated hyaluronic acid gel (15 mg/g) enriched with amino acids, antioxidants and lidocaine. The cannula technique used by Laser Esthetic's dermatologists is entirely painless thanks to the built-in lidocaine anaesthetic. Results are immediate and last a minimum of twelve months — significantly longer than most HA fillers in this area.
Hyaluronic acid lip filler injections to enhance lip volume, define the vermillion border, soften perioral lines and correct minor lip asymmetry. Laser Esthetic uses a range of HA products matched to the desired effect, with dental-block anaesthesia available for a comfortable session. Results are immediate, visible and adjustable in real time during the procedure. Duration is six to twelve months.
ABClinic Art & Beauty
V Parku 2308/8, 148 00 Praha 4 - Chodov, Czech Republic
ABClinic Art & Beauty is a leading plastic surgery and aesthetic medicine clinic in Prague. They are the only certified clinic in Czech Republic performing DHI hair transplantation with exclusive partnership with DHI Global Medical Group. Their facility in Prague 4 features three modern operating theaters and a team of experienced surgeons trained by the London Hair Restoration Training Academy.
Available Botox & Fillers:
ARS Clinic
Italská 1219/2, 120 00 Praha 2 - Vinohrady, Czech Republic
ARS Clinic is a new concept aesthetic medicine center in Prague's Vinohrady district that combines advanced medical technologies with artistic approach for natural, precise results. Services include lip enhancement, dermal fillers, anti-wrinkle injections, vector lifting, skinboosters, Aptos thread lifts, blepharoplasty, microneedling, and vitamin infusion therapy. The clinic also offers full diagnostic dermatology consultations.
Available Botox & Fillers:
Botulinum toxin treatment for dynamic wrinkles on forehead, crow's feet, and frown lines.
Hyaluronic acid filler for facial volume restoration and contouring.
Collagen stimulator treatment for facial lifting and volume restoration using calcium-based product.
How We Ranked These Clinics
Rankings are based on patient reviews, pricing transparency, and service quality for botox & fillers in Prague:
- ✓ Patient Reviews – Aggregated from Google and verified review platforms
- ✓ Pricing Transparency – Clear, upfront pricing published online
- ✓ International Services – English-speaking staff, patient coordinators
- ✓ Range of Services – Variety of botox & fillers options available
Data Sources
- Longevity.haus Database: Clinic listings with direct partnerships (Updated: 2026-06-04)
- Google Reviews: Aggregated ratings from Google Maps – Ratings may vary over time
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