10 Best Botox & Fillers Clinics in San Francisco (2026)

Mosaic Skin Studio is a medically supervised aesthetics practice co-founded by Stephanie Hwang, NP (Stanford Human Biology, UPenn BSN/MSN) and Dr. Chantal Lunderville, MD (UCLA Medical School, UCSF Family Medicine Residency). Located inside Pono Boutique at the corner of Diamond and Bosworth Streets in Glen Park — across from the BART station — the San Francisco studio emphasises science-backed skin care for diverse faces with a focus on prevention and inclusivity. Treatments include Botox, Xeomin, and Juvederm/RHA dermal fillers, SkinPen Precision microneedling (with optional PRP upgrade), HydraFacial, and customisable medical-grade chemical peels. Alle Payment Plans financing is available and a monthly Mosaic Fellowship membership provides 10% off injectables and ongoing credits. The studio holds a 4.9-star rating across 133 reviews. The SF Glen Park location operates Tuesdays and Thursdays; the Oakland Piedmont Ave flagship is the full-service location.

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Bay Area Cosmetic Dermatology is a physician-led cosmetic and medical dermatology practice founded in 2000 by Dr. Kathleen Welsh in Lower Pacific Heights, San Francisco. The practice operates the largest cosmetic laser center in the Bay Area, offering Fraxel re:pair CO2, Fraxel Duo, Fotona laser resurfacing, IPL photofacials, laser hair removal (Candela GentleLase, GentleYag, and Lumenis LightSheer DUET), and laser tattoo removal. With more than 5,000 BOTOX treatments administered annually, the injectable program spans BOTOX Cosmetic, Dysport, and Xeomin neurotoxins plus a comprehensive filler portfolio including Juvéderm, Restylane, Radiesse, Belotero, Sculptra, and KYBELLA. Advanced skin treatments include Morpheus8 RF microneedling, traditional microneedling via Micropen, and PRP therapy for hair loss and skin rejuvenation. Five board-certified dermatologists — including Newsweek-recognised 'America's Best Dermatologist' Dr. Steven Y. He — provide all treatments with physician-level oversight. The clinic also operates The Body Clinic at Bay Area Cosmetic Dermatology (Suite 304, same building) for body sculpting. Open Monday to Friday 8:00am–5:00pm. Google rating 4.8 stars across 231 reviews.

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Pacific Plastic Surgery Group is located at 77 Van Ness Avenue, Suite 302, in San Francisco's Civic Center district, steps from City Hall. The practice is led by Dr. Edward P. Miranda — Medical Director and board-certified plastic surgeon. Dr. Miranda earned his BS in Biochemistry with honors from Cornell, his MD with highest honors from Cornell Medical College, completed his plastic surgery residency and fellowship at UCSF, and completed a research fellowship at Memorial Sloan-Kettering. He is a member of the American Society of Plastic Surgeons (ASPS), the American Society for Aesthetic Plastic Surgery (ASAPS), and the American College of Surgeons (ACS), and was named a Castle Connolly Top Doctor. The surgical menu covers the full spectrum of plastic surgery: facelift (mini and full rhytidectomy), rhinoplasty with 3D imaging planning, breast augmentation with silicone cohesive gel, saline, or Ideal implants, eyelid surgery (upper and lower blepharoplasty), tummy tuck (standard, extended, panniculectomy, and diastasis recti repair, publicly priced at $8,000–$15,000), and body contouring via tumescent and VASER ultrasonic liposuction. The non-surgical division covers neuromodulators (Botox, Dysport, Xeomin), fillers (Juvederm, Radiesse, Restylane, Sculptra), IPL, fractionated CO2 laser (Nordlys), Nd:YAG laser, Ultherapy, chemical peels, microdermabrasion, microneedling with PRP (Vampire Facial), and facials. Financing is available via CareCredit and Prosper Healthcare Lending. Clinic hours are Monday to Friday 9 am–5 pm.

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The Maas Clinic is a nationally recognised facial plastic surgery practice located in San Francisco's Pacific Heights neighbourhood, founded and led by Dr. Corey S. Maas, MD, FACS. Dr. Maas is double board-certified by the American Board of Otolaryngology and the American Board of Facial Plastic and Reconstructive Surgery, with over 30 years of clinical experience and a record of more than 3,000 rhinoplasty procedures. He is the recipient of the Sir Harold Delf Gilles Award and directs a facial plastic surgery fellowship programme. The clinic campus at 2400 Clay Street spans three on-site facilities: the main surgical clinic, the Appearance Care Center med spa at 2408 Clay St., and the accredited SF Rejuvenation Center surgery suite at 2402 Clay St. Services range from the signature Deep Plane SMASplasty Facelift and complex revision rhinoplasty to injectable wrinkle relaxers and an extensive dermal filler portfolio. The practice holds a 4.8-star rating from 142 reviews.

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Mabrie Facial Institute is a Union Square practice dedicated entirely to non-surgical facial rejuvenation and contouring via injectables. Founded and led by Dr. David C. Mabrie MD — a board-certified facial plastic surgeon trained at Johns Hopkins and Stanford — the clinic has been voted Best BOTOX and Best Medical Spa in the Bay Area and holds a five-time Castle Connolly Top Doctor designation. Dr. Mabrie's proprietary Illumination 360° (i360) methodology studies how light falls across the face from every angle, then uses neuromodulators and dermal fillers to optimise structure and symmetry with no surgery required. The signature i360 Full Face programme combines up to 10 syringes of filler and 40 units of BOTOX across two or more appointments. The practice uses the full range of FDA-cleared products — JUVÉDERM, Restylane, Sculptra, RADIESSE, and KYBELLA — and offers treatments with both Dr. Mabrie and Physician Assistant injectors at accessible price points. Financing is available via CareCredit and Cherry.

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Aura Skin Spa Medical Corporation is a physician-led medical spa located in San Francisco's historic Jackson Square district. Founded and operated by board-certified physicians Dr. Ghausia Ata (Stanford-trained, aesthetic and anti-aging medicine) and Dr. Anthony Waechter (Emergency Medicine, 20+ years), the clinic brings medical oversight to a full range of aesthetic energy-device treatments. The clinical team also includes specialist aesthetic RNs with seven or more years of experience in laser therapies and injectables. The treatment menu covers laser hair removal using the Candela GentleMax Pro dual-wavelength system, Fraxel DUAL fractional resurfacing, Laser Genesis, and IPL PhotoFacials via the Lumenis One system. Skin tightening options include Thermage CPT radiofrequency, Sofwave ultrasound lifting, Pelleve RF, and Morpheus8 RF microneedling. Body contouring is delivered through Emsculpt HIFEM, Vanquish ME contactless RF, and VelaShape elōs technology. Microneedling uses the FDA-cleared Eclipse MicroPen EVO. Cherry financing of up to $10,000 is available, and the clinic runs monthly promotional packages. Open Tuesday through Saturday, closed Sunday and Monday.

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Elinea is an evidence-based medical spa located at 4035 18th Street in San Francisco's Castro District, founded and directed by Dr. Rami Hosein, MD, MPH — trained at UC Davis School of Medicine with a Harvard public health degree and Kaiser Permanente internal medicine residency. The clinical team includes a board-certified nurse practitioner with a DNP from Columbia, a physician assistant trained at Yale School of Medicine, an MSN-credentialed RN, and licensed estheticians specialising in advanced facial techniques. Treatments span the full range of medical aesthetics: Botox, Dysport, and dermal fillers (Restylane, Juvederm, Versa, Radiesse, Sculptra); SkinPen microneedling with AnteAGE stem cell post-care; Morpheus8 fractional RF microneedling with ProNox comfort option; IlluminatePRP for facial rejuvenation, under-eye treatment, and hair restoration; and VI Peel chemical peels. The clinic also offers BBL HERO laser, HALO Tribrid laser, MOXI, and HydraFacial. Booking is through Zenoti at visit.elineasf.com. Open Monday–Thursday 8:30am–7:00pm, Friday–Saturday 8:30am–5:00pm.

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Epi Center MedSpa, established in 1998 at 450 Sutter Street in San Francisco, is recognized as the nation's first medical spa and the country's first LEED eco-certified medspa (2008). It was co-founded by CEO Margaret Mitchell and cosmetic dermatologist Dr. Patrick H. Bitter Sr., M.D., who invented the IPL PhotoFacial procedure. The multilingual team represents 13 countries and speaks 11 languages. The practice holds Allergan Platinum status since 2002 and is ranked the number one Dysport provider in San Francisco. Services include BOTOX, Dysport, and dermal fillers (Juvederm, Restylane, Radiesse, Sculptra), Sofwave and Ultherapy non-surgical skin tightening, IPL PhotoFacial, ResurFX and CO2 fractional laser resurfacing, and microneedling including AquaGold, Morpheus8 RF, and PRF protocols. The clinic serves patients throughout the Bay Area, Monday to Saturday 9:30 AM to 6:00 PM.

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