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What Blood Tests Does Bryan Johnson Get for Longevity?

Quick Answer:

Bryan Johnson tracks 50+ biomarkers monthly including inflammation (CRP, IL-6), hormones (testosterone, thyroid), advanced lipids (ApoB, Lp(a)), metabolic markers (HbA1c, insulin), and cutting-edge aging tests (telomere length, NAD+ levels). Cost: ~$2,500/month.

Bryan Johnson's Blueprint Testing Protocol

Testing Frequency

Monthly

50+ biomarkers tracked

Annual Cost

$30K

Just for blood testing

Biological Age

18 years

Measured via epigenetic clocks

Bryan Johnson's Blueprint protocol aims to reverse biological aging through extreme data tracking and optimization. His blood testing regimen is the most comprehensive publicly documented longevity protocol.

Bryan Johnson's Core Blood Panel

Basic Health Markers

Complete Blood Count (CBC) with differential
Comprehensive Metabolic Panel (CMP)
Liver function tests (ALT, AST, ALP, bilirubin)
Kidney function (creatinine, BUN, eGFR)
Electrolytes (sodium, potassium, chloride)

Cardiovascular Risk

Advanced lipid panel (Total, HDL, LDL, triglycerides)
Apolipoprotein B (ApoB)
Lipoprotein(a) [Lp(a)]
Homocysteine
C-reactive protein (CRP)
Fibrinogen

Inflammatory Markers

High-sensitivity C-reactive protein (hs-CRP)
Interleukin-6 (IL-6)
Tumor necrosis factor-alpha (TNF-α)
Erythrocyte sedimentation rate (ESR)
Neutrophil-to-lymphocyte ratio

Hormone Panel

Thyroid panel (TSH, T3, T4, reverse T3)
Testosterone (total and free)
Estradiol
DHEA-S
Cortisol (morning)
Growth hormone (IGF-1)

Metabolic Health

Fasting glucose
HbA1c (glycated hemoglobin)
Insulin (fasting)
HOMA-IR (insulin resistance)
Leptin
Adiponectin

Nutritional Status

Vitamin D (25-hydroxyvitamin D)
Vitamin B12
Folate
Magnesium
Zinc
Omega-3 index (EPA/DHA ratio)

Advanced Blueprint Testing

Aging & Longevity

$500-1500 per test
Telomere length analysis
NAD+ levels
Biological age testing (methylation clocks)
Senescent cell markers
Autophagy markers

Genetic Testing

$200-800 per panel
APOE genotype
MTHFR mutations
Pharmacogenomics panel
Nutrient metabolism genes
Exercise response genes

Environmental Toxins

$300-600 per panel
Heavy metals panel
Mycotoxin testing
Pesticide residues
Phthalates and BPA
Air pollution markers

Bryan Johnson's Target Ranges vs Current Results

BiomarkerTarget RangeCurrent ResultSignificance
hs-CRP<0.5 mg/L0.3 mg/LUltra-low inflammation
HbA1c<5.0%4.8%Optimal glucose control
Testosterone700-900 ng/dL850 ng/dLYouthful hormone levels
Vitamin D60-80 ng/mL72 ng/mLImmune optimization
ApoB<80 mg/dL65 mg/dLCardiovascular protection
Homocysteine<7 μmol/L6.2 μmol/LVascular health

Monthly Testing Schedule

Week 1

$400-600

Core panel (CBC, CMP, lipids, hormones)

Week 2

$200-400

Inflammatory markers + nutritional status

Week 3

$300-500

Metabolic health + specialty markers

Week 4

$800-1200

Advanced aging biomarkers

Monthly Total: $1,700-2,700

Plus continuous glucose monitoring, sleep tracking, and other devices

Key Insights from Bryan Johnson's Protocol

What Makes It Unique

  • • Monthly frequency (vs quarterly for most)
  • • 50+ biomarkers (vs 20-30 typical)
  • • Advanced aging markers (telomeres, NAD+)
  • • Continuous monitoring integration
  • • Public data sharing for research

Proven Results

  • • 18-year-old biological age at 46
  • • Top 1% biomarkers for his age
  • • Significant improvement in all aging markers
  • • Documented reversal of biological aging
  • • Optimal inflammatory markers

How to Implement a "Blueprint-Inspired" Protocol

Budget Version

$200-400/month

Core biomarkers quarterly

  • • CBC, CMP, lipids
  • • CRP, HbA1c
  • • Thyroid, testosterone
  • • Vitamin D, B12

Comprehensive

$500-800/month

Extended panel monthly

  • • All basic markers
  • • Advanced lipids (ApoB, Lp(a))
  • • Inflammatory panel
  • • Hormone optimization

Blueprint-Level

$1500+/month

Full protocol replication

  • • 50+ biomarkers
  • • Telomere testing
  • • Genetic panels
  • • Continuous monitoring

Start Your Own Blueprint Protocol

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