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How Often Should I Get Blood Work Done for Health?

Complete guide to blood testing frequency for optimal health. Annual basics to quarterly optimization protocols across 49 providers.

Last updated: 2026-03-24

Quick Answer

Most healthy adults should get basic blood work annually, while those optimizing for longevity benefit from testing every 3-6 months. Frequency depends on your age, health status, and optimization goals. Compare testing options across 49 verified providers on Longevity.haus.

$7900

Starting price

49

Verified providers

1–86

Biomarkers per panel

1–12x

Tests per year

Blood Testing Frequency by Goal

How often you test depends on what you're optimizing for. Here are the three main tiers.

Tier 1

Basic Health Monitoring

Annual

Standard wellness checks for healthy individuals under 40. Covers CBC, metabolic panel, lipids, and thyroid.

Tier 2

Health Optimization

Every 3-6 Months

Tracking biomarkers for longevity and performance. Adds hormones, inflammatory markers, and advanced lipids.

Tier 3

Intensive Monitoring

Monthly

Advanced protocols like Bryan Johnson's Blueprint. 70+ biomarkers including micronutrients and aging markers.

Testing Frequency by Age

Recommended testing cadence shifts as you age, with more frequent and comprehensive panels after 40.

Age RangeFrequencyKey TestsNotes
20–30[1]AnnualCBC, metabolic panel, lipids (every 2-3yr), thyroidMore frequent if family history of disease
30–40[1][2]Semi-AnnualFull blood panel, hormones, HbA1c[3]Add inflammatory markers if optimizing
40–50[1][2]QuarterlyComprehensive panels, advanced lipids[2], cancer markers, nutrientsPSA and other cancer markers annually
50+[1][2]Quarterly+Full panels, cardiovascular (BNP, troponin), expanded cancer screeningBone density markers and hormones every 6mo

How Often Do Longevity Experts Test?

Two of the most prominent longevity figures take very different approaches to testing frequency and scope.

Bryan Johnson[4]

  • Frequency: Monthly comprehensive testing
  • Biomarkers: 70+ per draw
  • Imaging: Advanced imaging quarterly
  • Cost: ~$2,500/month
  • Philosophy: Data-maximalist, experimental, self-directed

Peter Attia[5]

  • Frequency: Quarterly optimization testing
  • Biomarkers: Focused panel, key markers
  • Imaging: Annual advanced testing
  • Cost: ~$800–1,500/quarter
  • Philosophy: Physician-guided, evidence-based

Frequently Asked Questions

Cost and Practical Considerations

Testing costs scale with frequency and comprehensiveness. Here's what to expect at each level.

Annual

Basic annual panel: $150–300/year

Quarterly

Comprehensive quarterly testing: $400–800 per test ($1,600–3,200/year)

Monthly

Advanced monthly monitoring: $1,000–2,500 per test ($12,000–30,000/year)

On Longevity.haus, blood testing starts from $7900 across 49 verified providers.

Most insurance covers annual wellness bloodwork. Optimization testing is typically out-of-pocket.

Based on 500 blood tests from 49 providers. Last updated 2026-03-24.

Sources & References

All recommendations are based on published clinical guidelines and expert protocols.

  1. USPSTF. "A and B Recommendations." U.S. Preventive Services Task Force. uspreventiveservicestaskforce.org
  2. AHA/ACC. "Guideline on the Management of Blood Cholesterol." Circulation, 2019. ahajournals.org
  3. ADA. "Standards of Care in Diabetes." 2024. diabetesjournals.org
  4. Johnson, B. "Blueprint Protocol." blueprint.bryanjohnson.com
  5. Attia, P. Outlive: The Science and Art of Longevity. Harmony Books, 2023.

Provider pricing data from Longevity.haus database. Last verified: 2026-03-24.

Find Blood Testing Near You

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