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How Often Should I Get Blood Work Done for Health?

Quick Answer

Most healthy adults should get basic blood work annually, while those optimizing for longevity benefit from testing every 3-6 months. Frequency depends on your age, health status, and optimization goals.

Blood Testing Frequency by Goal

Basic Health Monitoring

Annual

Standard wellness checks for healthy individuals under 40

Health Optimization

Every 3-6 Months

Tracking biomarkers for longevity and performance

Intensive Monitoring

Monthly

Advanced protocols like Bryan Johnson's Blueprint

Testing Frequency by Age

Ages 20-30: Annual Testing

  • Basic metabolic panel and CBC annually
  • Lipid panel every 2-3 years if normal
  • Thyroid function every 2-3 years
  • • More frequent if family history of disease

Ages 30-40: Semi-Annual Testing

  • Complete blood panel every 6-12 months
  • Hormone testing annually (testosterone, thyroid)
  • Inflammatory markers if optimizing health
  • HbA1c annually for diabetes screening

Ages 40+: Quarterly Testing

  • Comprehensive panels every 3-6 months
  • Advanced lipid testing quarterly
  • Cancer markers annually (PSA, etc.)
  • Nutrient levels every 6 months

How Often Do Longevity Experts Test?

Bryan Johnson

Monthly comprehensive testing including 70+ biomarkers

  • • Complete blood panel monthly
  • • Advanced imaging quarterly
  • • Cost: ~$2,500/month

Peter Attia

Quarterly optimization testing for patients

  • • Comprehensive panel every 3 months
  • • Annual advanced testing
  • • Cost: ~$800-1,500/quarter

Frequently Asked Questions

Can I test too often?

Generally no - blood testing is safe and non-invasive. However, testing more than monthly unless medically necessary can be expensive and may show normal fluctuations rather than meaningful trends.

What if my results are normal?

"Normal" ranges are often based on sick populations. Optimal ranges for longevity are typically tighter. Consider testing every 6 months to track trends even with "normal" results.

Should I fast before blood work?

12-hour fasting is required for accurate lipid and glucose testing. Most comprehensive panels require fasting. Hydrate well but avoid food, drinks (except water), and supplements.

Cost and Practical Considerations

Annual Testing Costs

  • Basic annual panel: $150-300
  • Comprehensive quarterly testing: $400-800 per test
  • Advanced monthly monitoring: $1,000-2,500 per test

Most insurance covers annual wellness bloodwork. Optimization testing is typically out-of-pocket.

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