Anaemia Panel (Anemický soubor)

VIDIA DIAGNOSTIKA's Anemický soubor (Anaemia Panel) combines seven iron and vitamin markers required to identify the cause of anaemia rather than simply confirm it: serum iron, TIBC/UIBC, transferrin, soluble transferrin receptor (sTfR), ferritin, folic acid and vitamin B12. Together they distinguish iron-deficiency anaemia from B12-deficiency megaloblastic anaemia, folate deficiency, anaemia of chronic disease and functional iron deficiency — conditions that look similar on a standard blood count but require completely different treatment.

The Anemický soubor (Anaemia Panel) at VIDIA DIAGNOSTIKA is a seven-marker investigation designed to answer a question that the basic complete blood count (CBC) cannot: why is the haemoglobin low? The haemoglobin value and red cell indices (MCV, MCH) on a CBC indicate that anaemia is present and whether red cells are small, large or normal-sized, but they cannot identify the underlying cause. The Anemický soubor provides the mechanistic data to do so. The panel includes serum iron (Fe), which reflects circulating iron available for haemoglobin synthesis; total iron-binding capacity (TIBC) and unsaturated iron-binding capacity (UIBC), which together quantify the unused transport capacity of transferrin; transferrin itself, the primary iron-transport protein whose level inversely correlates with iron stores; soluble transferrin receptor (sTfR), which rises specifically in tissue iron deficiency and is useful for distinguishing true iron deficiency from anaemia of chronic inflammation (where sTfR remains normal); ferritin, the storage form of iron and the most sensitive marker of total body iron — low ferritin is definitive for iron deficiency even when haemoglobin is still normal; folic acid (vitamin B9), deficiency of which causes megaloblastic anaemia with macrocytic red cells; and vitamin B12 (cobalamin), another megaloblastic anaemia cause whose deficiency may also cause neurological symptoms that precede the blood changes. Clinically, the combination allows the physician to separate the four main diagnostic categories: iron-deficiency anaemia (low Fe, high TIBC, low ferritin, high sTfR); anaemia of chronic disease (low or normal Fe, low or normal TIBC, normal or high ferritin, normal sTfR — ferritin is an acute-phase reactant elevated in inflammation); functional iron deficiency (normal ferritin but high sTfR, seen in erythropoietin-treated renal patients); and megaloblastic anaemia (large red cells, low B12 or folate). At VIDIA DIAGNOSTIKA, the panel is available across 30 collection sites with results returned via the patient portal. Individual components can be ordered separately for targeted retesting — ferritin at 335 Kč, B12 at 374 Kč, folate at 370 Kč, sTfR at 429 Kč. No fasting is strictly required for most markers in this panel, though fasting is advisable to reduce serum iron variability from recent dietary intake.