Type
Regenerative Therapy
Duration
30 min
What's included
5 deliverables in this treatment
- Morning venous blood draw (~60 ml) and same-day serum incubation (8–9 hours at 37°C in cultivation device)
- Six serially numbered injection aliquots prepared from a single blood draw
- Afternoon injection into the target joint or tendon by MUDr. Jiří Neumann on day 1
- Five follow-up injection appointments every 5–7 days over approximately 30 days
- Post-treatment guidance and monitoring throughout the course
Orthokine is an autologous biological joint therapy in which the patient's own blood is drawn, specially incubated to concentrate anti-inflammatory cytokines (including IL-1Ra) at levels up to 140 times their baseline concentration, and then injected into the affected joint or tendon. Unlike corticosteroid injections, which suppress inflammation systemically and may weaken cartilage over time, Orthokine introduces the body's own regulatory proteins to interrupt the inflammatory cycle at its source — without synthetic drugs. Sportklinik is one of only a handful of Czech clinics offering this protocol, with MUDr. Jiří Neumann performing all procedures. A standard course is 6 applications over approximately 30 days.
About this treatment
Orthokine belongs to the class of autologous conditioned serum (ACS) therapies — a regenerative medicine approach that uses the patient's own biological material, modified ex-vivo, to reduce joint inflammation and slow cartilage degradation. The mechanism centres on interleukin-1 receptor antagonist (IL-1Ra): IL-1 is a key pro-inflammatory cytokine elevated in osteoarthritic and acutely inflamed joints, and IL-1Ra is its natural counter-regulator. In…
The procedure at Sportklinik follows a same-day two-visit protocol. In the morning, the physician (MUDr. Jiří Neumann) performs a venous blood draw of approximately 60 ml. The blood is transferred to specially coated glass spheres inside a sealed cultivation device and incubated at 37°C for 8–9 hours — during which the spheres trigger the leucocytes to produce concentrated cytokine serum. The serum is centrifuged, filtered, and divided into 6 aliquots for…
Indications at Sportklinik include arthrosis/osteoarthritis of large joints (knee, hip, shoulder, ankle) at stages I–III of the Kellgren–Lawrence grading, post-arthroscopic rehabilitation, tendinopathies that have not responded to conservative management (tennis elbow, Achilles tendinopathy), and selected cases of spinal disc-related pain. The clinic emphasises that Orthokine is not a cure for end-stage joint disease but can substantially reduce pain,…
Good to know
- Method
- Autologous conditioned serum (ACS)
- Cytokine amplification
- IL-1Ra up to 140× baseline
- Course
- 6 injections over ~30 days
- Anaesthesia
- Not required (local anaesthesia available)
- Availability
- One of only a few Czech providers
Who is this for?
Osteoarthritis stages I–III (knee, hip, shoulder, ankle), chronic tendinopathies unresponsive to conservative care, post-arthroscopy rehabilitation, patients seeking to delay or avoid joint replacement
Booking options & clinic offers
Loyalty card 900 Kč/year (5% discount on all services). Premium loyalty card 2,900 Kč/year (10% discount, priority appointments, 3 hydro/lymph massage vouchers).
Preparation required
Morning blood draw requires a short fast (water permitted). Avoid NSAIDs and systemic anti-inflammatory medication throughout the treatment course. Rest the treated area for 24 hours after each injection. No sauna or strenuous exercise for 48 hours post-injection.
About the clinic
Reviews, team and credentials
Independent review links and clinic-reported team information.
Clinical team
Sportklinik is led by MUDr. Jiří Neumann, owner, board-certified surgeon, sports medicine physician, and chief medical officer to Czech Olympic team athletes. The medical team includes MUDr. Tomáš Vašátko and MUDr. Igor Moose as attending physicians, supported by nurse Veronika Nováková. The physiotherapy team comprises five qualified practitioners: Bc. Pavla Macháčková, Mgr. Martina Hobzová, Mgr. Pavlína Holečková,…
Languages: cs, en
Treatment highlights
- Morning venous blood draw (~60 ml) and same-day serum incubation (8–9 hours at 37°C in cultivation device)
- Six serially numbered injection aliquots prepared from a single blood draw
+3 more items in What's included
Price available on request — contact MUDr. Neumann directly at +420 604 935 240. A standard course consists of 6 injections over approximately 30 days. Each appointment involves a morning blood draw, a day of serum incubation, and an afternoon injection visit. Sportklinik is one of only a handful of Czech facilities offering this treatment.