Problem Wound Management with HBOT

The SGH Problem Wound Management programme pairs hyperbaric oxygen therapy with dedicated wound care expertise to address complex, non-healing wounds that have failed to respond adequately to conventional treatment. Managed by specialist physicians and wound care nurses within Singapore General Hospital, this programme is designed for patients with wounds that are clinically stalled — where tissue ischaemia, infection, radiation damage, or underlying…

Hyperbaric oxygen therapy is a cornerstone of the programme's mechanism of action. Breathing 100% oxygen at elevated atmospheric pressure (2 to 3 ATA) raises tissue oxygen tension to levels far beyond what breathing room air at sea level can achieve. This hyperoxic environment stimulates fibroblast proliferation, collagen synthesis, angiogenesis (new blood vessel formation), and immune cell bactericidal activity — all of which are critical components of…

The primary wound types managed in this programme include diabetic foot ulcers at high risk of amputation, venous stasis ulcers refractory to compression therapy, radiation tissue injury (including osteoradionecrosis of the jaw following head and neck radiotherapy, and radiation cystitis or proctitis), refractory osteomyelitis where bone infection has failed to clear with antibiotics and surgery, compromised skin grafts and flaps in post-surgical…