Labor 28 Berlin
Medical laboratory in Berlin-Wilmersdorf offering direct-to-consumer blood testing via Mein Direktlabor platform with transparent GOÄ pricing, physician consultations, same-day results, and comprehensive preventive health packages from basic check-ups to specialized hormone and micronutrient testing.
Labor 28 MVZ GmbH is a well-established medical laboratory serving Berlin for 47 years, part of the international Sonic Healthcare network. With 17 medical specialists and 350 employees, the laboratory provides comprehensive diagnostic services across clinical chemistry, microbiology, virology, and infection epidemiology. For direct consumers, Labor 28 partners with Mein Direktlabor platform to offer self-pay blood testing without physician referral. Located in Berlin-Wilmersdorf at Mecklenburgische Straße 28, the laboratory features modern automated sample processing with strict quality assurance standards (ISO 15189 accredited). Direct consumer services include: preventive health packages from €63.66-€538.25, hormone panels for men/women/thyroid (€147.47-€248.03), specialized testing for osteoporosis (€207.10), hair loss assessment (€211.81), sports performance optimization (€188.34), cardiovascular risk (€93.16), and comprehensive micronutrient profiling. All testing follows German Medical Fee Schedule (GOÄ) pricing. Unique features: same-day results for most tests, physician consultation services for result interpretation, blood sampling by appointment Monday-Friday (9:00-17:00, Wednesday until 18:00), online appointment booking via Doctolib. The laboratory emphasizes personalized result discussions with laboratory doctors, ensuring patients understand clinical significance of findings. Comprehensive testing spectrum allows investigation of nutrient deficiencies (vitamins D/B12/C/E/K, minerals, amino acids), hormonal imbalances (thyroid, reproductive, stress hormones), metabolic health (diabetes, lipid disorders), cardiovascular risk factors, bone health, athletic performance optimization. Results delivered via patient portal with 8-digit order number, typically available within 1-3 days depending on test complexity. Pricing transparency via published 2024 price list includes individual test costs (basic tests from €2.68, specialized tests up to €40+) and package bundles offering comprehensive screening at reduced rates. Ideal for health-conscious individuals seeking regular monitoring, athletes optimizing performance, vegetarians/vegans checking nutritional status, preventive health screening before symptoms arise.
Locations
Treatments
Basis-Check (Basic Health Screening)
Comprehensive basic health screening analyzing 18 biomarkers for cardiovascular, metabolic, liver, kidney, and thyroid function. Venous blood sample with 12-hour fasting required for accurate glucose and lipid measurements. Results typically same-day or within 24 hours via patient portal. Appointment booking via Doctolib, blood sampling Monday-Friday (9:00-17:00, Wednesday until 18:00). GOÄ fee schedule pricing. Essential annual health check covering all major organ systems for disease prevention and early detection. Biomarkers tested: Blood Count - complete blood count (CBC) with differential detecting anemia, infection, inflammation, immune disorders including RBC, WBC, hemoglobin, hematocrit, platelets, neutrophils, lymphocytes, monocytes, eosinophils, basophils; Metabolism - fasting glucose (diabetes screening), HbA1c (glycated hemoglobin reflecting 2-3 month glucose average, gold standard diabetes marker), uric acid (gout risk, kidney function); Cardiovascular - total cholesterol, HDL cholesterol ("good"), LDL cholesterol ("bad"), triglycerides (fat metabolism, cardiovascular risk); Liver - GPT/ALAT (liver inflammation, cell damage), GOT/ASAT (liver and heart damage), bilirubin (bile flow, liver function, hemolysis), alkaline phosphatase (liver and bone enzyme); Kidney - creatinine (filtration capacity), urea (protein metabolism, kidney function); Electrolytes - sodium (fluid balance, blood pressure), potassium (heart rhythm, nerve/muscle function), calcium (bone health, nerve transmission, muscle contraction). Comprehensive panel efficiently screens for: diabetes/prediabetes, cardiovascular disease risk, liver disease (hepatitis, fatty liver, alcohol damage), kidney dysfunction, anemia, electrolyte imbalances, metabolic syndrome. Ideal for annual health monitoring, establishing health baseline, or investigating non-specific symptoms (fatigue, weakness). Price €63.66 includes blood draw (€4.20) and all analyses.
€63.66
Herz-Kreislauf-Check (Cardiovascular Risk Assessment)
Advanced cardiovascular risk screening analyzing 10 biomarkers for heart attack, stroke, and atherosclerosis risk assessment. Venous blood sample with 12-hour fasting required. Same-day results available. Essential for: family history of heart disease, over age 40, smokers, diabetes, hypertension, high cholesterol, obesity, sedentary lifestyle. Identifies modifiable risk factors before cardiovascular events occur. Biomarkers tested: Lipid Panel - total cholesterol (overall risk), HDL cholesterol ("good" protective cholesterol, target >40 mg/dL men, >50 mg/dL women), LDL cholesterol ("bad" cholesterol causing arterial plaque, target <100 mg/dL, <70 mg/dL high-risk patients), triglycerides (fat metabolism, independent risk factor when elevated); Advanced Cardiovascular Markers - lipoprotein(a) [Lp(a)] (genetic cardiovascular risk factor unaffected by lifestyle, strong predictor of heart attack/stroke even with normal cholesterol, elevated levels >30 mg/dL require aggressive LDL management), homocysteine (amino acid, elevated levels (>15 µmol/L) damage arterial walls promoting atherosclerosis, linked to B vitamin deficiency); Blood Count - complete blood count (anemia affects oxygen delivery to heart, polycythemia increases blood viscosity and clot risk); Metabolism - fasting glucose (diabetes damages vessels accelerating atherosclerosis), HbA1c (long-term glucose control, diabetes/prediabetes screening); Kidney - creatinine (kidney disease accelerates cardiovascular disease). Panel provides comprehensive cardiovascular risk stratification beyond basic cholesterol testing. Lp(a) testing particularly valuable as this genetic risk factor often overlooked in standard screening but affects 20% of population. Homocysteine identifies treatable risk factor (lowered with B vitamins). Results guide: statin therapy initiation, aspirin therapy, blood pressure management, diabetes treatment, lifestyle modifications (diet, exercise, smoking cessation). Recommended frequency: baseline age 40, annually if high risk, every 3-5 years if low risk. GOÄ pricing €93.16.
€93.16
Diabetes Mellitus Screening
Focused diabetes screening panel analyzing 2 key glucose biomarkers for diabetes diagnosis and monitoring. Venous blood sample with 12-hour fasting required for accurate fasting glucose measurement. Results within 24 hours. Essential for: family history of diabetes, overweight/obesity (BMI >25), sedentary lifestyle, history of gestational diabetes, prediabetes diagnosis, unexplained fatigue/thirst/urination. American Diabetes Association and German guidelines recommend screening every 3 years for adults over 45, annually if risk factors present. Biomarkers tested: Fasting Glucose - blood sugar after overnight fast, diagnostic criteria: <100 mg/dL normal, 100-125 mg/dL prediabetes, ≥126 mg/dL diabetes (requires confirmation), detects current glycemic control but only snapshot of one moment; HbA1c (Glycated Hemoglobin) - percentage of hemoglobin with attached glucose, reflects average blood sugar over past 2-3 months (lifespan of red blood cells), diagnostic criteria: <5.7% normal, 5.7-6.4% prediabetes, ≥6.5% diabetes, gold standard for diabetes diagnosis and monitoring, not affected by recent meals or daily fluctuations, correlates directly with diabetes complications risk (every 1% increase in HbA1c increases microvascular complications ~30%). Panel advantages: fasting glucose detects current dysglycemia, HbA1c confirms chronic hyperglycemia and tracks long-term control, combination improves diagnostic sensitivity. Early diabetes detection enables: lifestyle interventions preventing progression (weight loss, exercise, diet), metformin therapy for prediabetes, avoiding complications (neuropathy, retinopathy, nephropathy, cardiovascular disease). For diagnosed diabetics, panel monitors treatment effectiveness (target HbA1c <7% for most, <6.5% for some, individualized). Cost-effective focused screening €16.09, can be added to any package. Recommended frequency: prediabetes every 3-6 months, established diabetes every 3 months. GOÄ pricing.
€16.09
Sport Check-up (Athletic Performance & Recovery Panel)
Comprehensive athletic performance optimization panel analyzing 20+ biomarkers for energy production, muscle function, recovery capacity, and nutritional adequacy. Venous blood sample, fasting recommended. Results within 2-3 days. Essential for: competitive athletes, endurance training, strength training, masters athletes, performance plateaus, slow recovery, recurring injuries, fatigue despite training. Identifies limiting factors preventing optimal performance and adaptation. Biomarkers tested: Blood Count - complete CBC detecting sports anemia (dilutional or iron deficiency), overtraining syndrome (altered WBC differential), adequate oxygen carrying capacity (hemoglobin/hematocrit); Energy Metabolism - glucose (fuel availability), lipid panel (total cholesterol, HDL, LDL, triglycerides - athletes should have optimal lipids despite high caloric intake, abnormal values suggest metabolic dysfunction or dietary issues); Liver - liver enzymes (GPT, GOT, elevated with overtraining or muscle damage, chronically high suggests inadequate recovery); Kidney - creatinine (filtration, muscle breakdown marker especially in strength athletes); Inflammation - CRP (C-reactive protein, acute training stress increases CRP, chronically elevated suggests inadequate recovery or overtraining); Thyroid - TSH (thyroid stimulating hormone, hypothyroidism causes fatigue, weight gain, poor performance, common in athletes especially female with low energy availability/RED-S); Minerals Essential for Performance - magnesium (muscle contraction, energy production, 300+ enzymatic reactions, deficiency causes cramps, fatigue, impaired recovery), calcium (muscle contraction, bone health, neurotransmission), zinc (immune function, testosterone production, wound healing, taste/appetite - low in athletes from sweat losses), selenium (antioxidant, immune function, thyroid conversion); Iron Status - ferritin (iron stores, most sensitive marker of iron deficiency before anemia develops, athletes especially endurance/female at high risk from increased needs, GI losses, foot strike hemolysis, low ferritin causes fatigue, reduced endurance, impaired adaptation to training); Vitamins - vitamin D (bone health, immune function, muscle function, testosterone production, 40-60% athletes deficient especially winter/indoor sports, optimal levels 40-60 ng/mL for performance), amino acids (building blocks for muscle protein synthesis, recovery, neurotransmitter production, imbalances suggest inadequate protein intake or absorption). Panel provides: nutritional deficiency identification (correct before supplementing), overtraining detection (elevated CRP, altered hormones/blood counts), thyroid dysfunction screening (common in athletes), iron status assessment (prevent/treat sports anemia), metabolic health verification. Results guide: targeted supplementation (iron, vitamin D, magnesium based on actual deficiency), training load adjustment (reduce if inflammatory markers high), nutrition optimization (adequate protein, micronutrients), injury risk reduction. Recommended: baseline before training season, every 6 months during heavy training, when performance plateaus or declines unexpectedly. GOÄ pricing €188.34.
€188.34
Mikronährstoffprofil Basis (Basic Micronutrient Profile)
Comprehensive micronutrient screening analyzing 15 essential vitamins, minerals, and metabolic markers for nutritional adequacy, disease prevention, and optimal health. Venous blood sample, fasting recommended for accurate amino acid profile. Results within 3-5 days. Essential for: fatigue, weakness, immune dysfunction, poor wound healing, neurological symptoms, hair loss, skin problems, vegetarian/vegan diets, malabsorption disorders, pregnancy/breastfeeding, elderly, chronic disease, athletic performance optimization. Identifies subclinical deficiencies before overt disease develops. Biomarkers tested: Iron Status - ferritin (iron stores, earliest marker of iron deficiency causing fatigue, weakness, anemia, immune dysfunction, impaired cognition), vitamin B12 (cobalamin, essential for red blood cell formation, neurological function, DNA synthesis, deficiency causes anemia, neuropathy, cognitive decline, vegans/elderly at high risk); Bone & Cardiovascular Health - vitamin D (25-OH-D, hormone regulating calcium, bone density, immune function, mood, optimal levels 40-60 ng/mL, 40-80% population deficient especially winter/northern climates), calcium (bone health, muscle contraction, nerve transmission, heart rhythm), vitamin K1/K2 (K1 for blood clotting, K2 for bone mineralization and preventing arterial calcification, deficiency causes osteoporosis and cardiovascular disease), homocysteine (amino acid, elevated levels (>10 µmol/L) indicate B vitamin deficiency and cardiovascular/cognitive risk, lowered with folate/B12/B6 supplementation); Cardiovascular & Nerve Health - magnesium (300+ enzymatic reactions, muscle relaxation, blood pressure regulation, glucose metabolism, deficiency causes cramps, arrhythmias, hypertension); Antioxidant Vitamins - vitamin A (immune function, vision, skin health, reproduction), vitamin C (collagen synthesis, immune function, iron absorption, antioxidant), vitamin E (fat-soluble antioxidant protecting cell membranes, cardiovascular/cognitive health); B Vitamins - vitamin B1/thiamine (energy metabolism, nerve function, deficiency causes beriberi and Wernicke-Korsakoff syndrome), vitamin B2/riboflavin (energy production, antioxidant regeneration, migraine prevention), vitamin B6/pyridoxine (amino acid metabolism, neurotransmitter synthesis, immune function, homocysteine metabolism); Trace Minerals - zinc (immune function, wound healing, taste/smell, testosterone production, DNA synthesis, 300+ enzymes), selenium (thyroid hormone conversion, antioxidant, immune function, cancer prevention); Protein Status - plasma amino acids (complete profile of 20+ amino acids, detects protein malnutrition, absorption issues, metabolic disorders, guides protein intake adequacy). Comprehensive panel efficiently identifies: vitamin D insufficiency (extremely common), iron deficiency (women, vegetarians, athletes), B12 deficiency (vegans, elderly, metformin users, PPI users), magnesium deficiency (stress, diabetes, GI disorders), elevated homocysteine (B vitamin deficiency, cardiovascular risk), zinc/selenium deficiency (immune/thyroid dysfunction). Results guide targeted supplementation avoiding dangerous megadosing. Recommended annually for health monitoring, every 6 months if deficiency risk factors. GOÄ pricing €180.96.
€180.96
Mikronährstoffprofil Kompakt (Comprehensive Micronutrient Profile)
Ultra-comprehensive micronutrient analysis adding 9 advanced markers to Basic profile for total 24 biomarkers. Total price €719.21 (€180.96 Basic + €538.25 additional). Venous blood sample, fasting required. Results within 5-7 days. Most complete nutritional assessment available for: chronic disease, malabsorption, optimal longevity, complex symptoms, therapeutic monitoring, precision nutrition optimization. All Basic profile markers PLUS: Advanced Antioxidants - total antioxidative capacity (TAC, measures overall antioxidant defense system beyond individual vitamins, low TAC indicates oxidative stress from inadequate antioxidant intake, chronic inflammation, excessive free radical production), glutathione (master intracellular antioxidant, detoxification, immune function, declines with age/stress/chronic disease, marker of cellular health); Energy Production - carnitine (transports fatty acids into mitochondria for energy production, essential for fat metabolism and endurance, deficiency causes muscle weakness, fatigue, cardiomyopathy), coenzyme Q10 (CoQ10, ubiquinone, electron transport chain component producing ATP, powerful antioxidant, heart health, declines with age and statin use causing muscle pain/weakness); Cardiovascular & Metabolic - fatty acid status (comprehensive profile of omega-3, omega-6, omega-9, saturated fats, trans fats, omega-3 index critical for cardiovascular/brain health, optimal EPA+DHA >8%, identifies fat metabolism disorders), copper (ceruloplasmin, iron metabolism, connective tissue formation, nervous system, excess or deficiency causes problems, must balance with zinc); Vitamins - biotin (vitamin B7/H, carbohydrate/fat/protein metabolism, hair/skin/nail health, high-dose biotin supplementation can falsely alter lab results), folate (vitamin B9, DNA synthesis, cell division, prevents neural tube defects in pregnancy, lowers homocysteine, different from folic acid supplement form, measures active natural folate); Thyroid - iodine (essential for thyroid hormone synthesis, deficiency causes hypothyroidism and goiter, 30% global population deficient, excess also problematic, optimal range narrow). Comprehensive profile provides: complete nutritional status assessment beyond standard testing, oxidative stress evaluation (TAC, glutathione), mitochondrial function assessment (CoQ10, carnitine), omega-3 status (inflammatory balance), trace mineral optimization (copper, iodine), B vitamin completion (biotin, folate beyond B12). Clinical applications: chronic fatigue investigation (CoQ10, carnitine, iron, thyroid), cardiovascular optimization (omega-3 index, homocysteine, antioxidants), cognitive decline prevention (omega-3, B vitamins, antioxidants), athletic performance (all of above plus amino acids, minerals), pregnancy preparation (folate, iodine, iron, omega-3), anti-aging/longevity protocols (comprehensive optimization). Results enable precision supplementation targeting actual deficiencies rather than guessing. Most cost-effective comprehensive micronutrient assessment compared to individual test pricing. Recommended: baseline health optimization, annually for longevity-focused individuals, therapeutic monitoring. GOÄ pricing.
€538.25
Haarausfall (Hair Loss Assessment Panel)
Specialized diagnostic panel for hair loss (alopecia) analyzing 12 biomarkers across thyroid, hormones, nutrients, and inflammation affecting hair growth. Venous blood sample, no fasting required though morning collection preferred for hormones. Results within 3-5 days. Essential investigating: increased hair shedding, thinning hair, bald patches, hair texture changes, slow growth. Hair loss causes: androgenetic alopecia (genetic), telogen effluvium (stress/illness), thyroid disease, iron deficiency, hormonal imbalances, nutritional deficiencies, autoimmune (alopecia areata). Biomarkers tested: Blood Count - small blood count (CBC, anemia associated with hair loss, especially iron deficiency anemia); Inflammation - CRP (C-reactive protein, acute/chronic inflammation, autoimmune conditions causing hair loss including alopecia areata); Thyroid - TSH (thyroid stimulating hormone, both hypothyroidism and hyperthyroidism cause diffuse hair loss, brittle hair, altered texture, thyroid disease very common especially women); Minerals - ferritin (iron stores, low ferritin (<40 ng/mL) strongly associated with hair loss even without anemia, women/vegetarians/heavy periods at risk, most common correctable cause), zinc (essential for hair follicle function, protein synthesis, cell division, deficiency causes hair loss, slow growth, brittle hair), selenium (antioxidant, thyroid function, hair health, both deficiency and excess can cause hair loss); Female Hormones - LH (luteinizing hormone), FSH (follicle-stimulating hormone), estradiol (E2, primary estrogen), progesterone (reproductive hormones, imbalances cause hair loss - menopause, PCOS, perimenopause, high androgens in PCOS cause male-pattern hair loss in women); Androgens - DHEA-S (dehydroepiandrosterone sulfate, adrenal androgen precursor, elevated in PCOS associated with androgenetic hair loss), testosterone (in women, elevated testosterone/DHEA-S suggest PCOS or other androgen excess causing male-pattern hair loss, miniaturized hair follicles). Panel identifies most common treatable causes: iron deficiency (supplement iron, investigate source of loss), thyroid dysfunction (levothyroxine for hypothyroidism), PCOS/androgen excess (spironolactone, metformin, oral contraceptives), zinc/selenium deficiency (supplementation). Combined interpretation critical - for example, woman with elevated LH:FSH ratio (>2:1), elevated DHEA-S/testosterone, suggests PCOS; low ferritin alone explains diffuse shedding. Recommended for any unexplained hair loss before expensive treatments (minoxidil, finasteride). Note: panel designed for female hormone assessment; male hair loss typically androgenetic (genetic DHT sensitivity) requiring different evaluation (see Male Hormone Panel). Results guide: iron supplementation (if ferritin <40), thyroid medication (if TSH abnormal), PCOS treatment (if androgens elevated), nutritional correction (zinc, selenium). Hair regrowth takes 3-6 months after correcting deficiency. Follow-up testing recommended 3-6 months post-treatment. GOÄ pricing €211.81.
€211.81
Hormonstatus Mann (Male Hormone Panel)
Comprehensive male hormone panel analyzing 7 key hormones regulating energy, libido, muscle mass, mood, fertility, and metabolic health. Venous blood sample collected morning (7-10 AM) when testosterone peaks. Results within 2-3 days. Essential for: low energy/fatigue, decreased libido, erectile dysfunction, difficulty building muscle, increased body fat, mood disorders, infertility, age over 40. Testosterone declines ~1% annually after age 30; symptomatic hypogonadism affects 20% men over 60. Biomarkers tested: Testosterone (total) - primary male sex hormone, normal range 300-1000 ng/dL, levels <300 ng/dL diagnostic for hypogonadism, affects muscle mass, bone density, libido, mood, energy, cognition, cardiovascular health, fat distribution, erythropoiesis; SHBG (sex hormone-binding globulin) - protein binding testosterone in blood, only unbound "free" testosterone bioavailable to tissues, high SHBG (from aging, hyperthyroidism, liver disease) reduces free testosterone despite normal total testosterone, low SHBG (obesity, hypothyroidism, insulin resistance) increases free testosterone, free testosterone calculated from total testosterone + SHBG using formula; FSH (follicle-stimulating hormone) - in men stimulates spermatogenesis (sperm production) in Sertoli cells of testes, elevated FSH with low testosterone indicates primary testicular failure (testes not responding to pituitary signals), normal/low FSH with low testosterone suggests secondary hypogonadism (pituitary/hypothalamic dysfunction); LH (luteinizing hormone) - stimulates testosterone production by testicular Leydig cells, interpretation parallels FSH (high LH+low testosterone = primary testicular problem, low LH+low testosterone = central hypogonadism from pituitary/hypothalamic causes); Prolactin - pituitary hormone, elevated prolactin (>20 ng/mL) suppresses GnRH release reducing LH/FSH and testosterone, causes hypogonadism, erectile dysfunction, gynecomastia, galactorrhea, caused by prolactinoma (pituitary tumor), medications (antipsychotics, metoclopramide), hypothyroidism; TSH (thyroid stimulating hormone) - hypothyroidism causes low testosterone, fatigue, weight gain, erectile dysfunction mimicking hypogonadism, hyperthyroidism increases SHBG reducing free testosterone; DHEA-S (dehydroepiandrosterone sulfate) - adrenal androgen precursor providing additional androgens beyond testicular testosterone, declines with age, low DHEA-S suggests adrenal insufficiency, provides substrate for peripheral testosterone conversion. Panel distinguishes: primary hypogonadism (testicular failure - high LH/FSH, low testosterone, causes: aging, chemotherapy, trauma, infection, genetic), secondary hypogonadism (pituitary/hypothalamic - low LH/FSH, low testosterone, causes: obesity, opioids, pituitary tumor, Kallmann syndrome), hyperprolactinemia (high prolactin suppressing axis), thyroid dysfunction. Results guide: testosterone replacement therapy (TRT) evaluation (if total testosterone <300 ng/dL with symptoms), fertility assessment (FSH/LH elevated suggests poor sperm production), thyroid treatment (if TSH abnormal), prolactinoma investigation (MRI if prolactin >50), lifestyle modifications (weight loss, sleep, stress, alcohol reduction increase testosterone). Important: TRT contraindicated if fertility desired (suppresses FSH/LH/spermatogenesis), prostate cancer, severe BPH, uncontrolled heart failure. Recommended: baseline age 40, annually if symptomatic or on TRT, repeat 3-6 months after TRT initiation to verify response and adjust dose. GOÄ pricing €150.82.
€150.82
Hormonstatus Frau (Female Hormone Panel)
Comprehensive female reproductive hormone panel for women of childbearing age analyzing 10 hormones regulating menstrual cycles, fertility, ovulation, mood, metabolic health, and ovarian reserve. Venous blood sample with critical timing - ideally Day 3-5 of menstrual cycle for FSH/LH/estradiol/AMH (early follicular phase), Day 21 for progesterone (mid-luteal phase, or 7 days before expected period). Results within 3-5 days. Essential for: irregular periods, fertility issues, PCOS investigation, unexplained weight gain, mood disorders, low libido, PMS symptoms, perimenopause concerns, assessing ovarian reserve before fertility treatment. Biomarkers tested: FSH (follicle-stimulating hormone) - controls ovarian follicle maturation and egg development, Day 3 FSH levels predict ovarian reserve (low reserve if FSH >10-15 IU/L, approaching menopause if >25 IU/L), very high FSH (>40 IU/L) indicates ovarian failure/menopause, cyclic FSH rises select dominant follicle for ovulation; LH (luteinizing hormone) - triggers ovulation mid-cycle releasing mature egg, LH:FSH ratio diagnostic for PCOS (ratio >2:1 suggests PCOS with multiple small follicles and anovulation), absent LH surge indicates anovulation (no ovulation occurring); Estradiol (E2) - primary estrogen hormone, regulates menstrual cycle, maintains endometrium, bone density, cardiovascular health, brain function, libido, skin/hair quality, Day 3 levels should be low (<50-80 pg/mL for normal ovarian function, elevated Day 3 estradiol suggests diminished ovarian reserve or ovarian cyst), rises during follicular phase peaking just before ovulation, low estradiol causes irregular periods, hot flashes, vaginal dryness, bone loss; Progesterone - produced by corpus luteum after ovulation, maintains early pregnancy, balances estrogen, thickens endometrium for implantation, Day 21 progesterone confirms ovulation occurred (levels >10 ng/mL indicate ovulation, <10 ng/mL suggest anovulation or luteal phase defect causing infertility/miscarriage), low progesterone causes irregular bleeding, PMS, anxiety, insomnia; Testosterone - androgen affecting libido, energy, muscle mass, mood in women, mildly elevated testosterone common in PCOS (along with high LH:FSH ratio), very high testosterone suggests other androgen excess disorders; SHBG (sex hormone-binding globulin) - binds testosterone and estrogen, low SHBG (from insulin resistance, obesity, PCOS) increases free androgens worsening PCOS symptoms (acne, hirsutism, hair loss); Prolactin - elevated prolactin (>25 ng/mL) suppresses GnRH release causing anovulation, irregular periods, infertility, galactorrhea, caused by prolactinoma, medications, hypothyroidism, stress; TSH (thyroid stimulating hormone) - thyroid dysfunction causes menstrual irregularities, anovulation, infertility, both hypothyroidism (irregular heavy periods, weight gain) and hyperthyroidism (light/absent periods, weight loss) disrupt reproduction; DHEA-S (dehydroepiandrosterone sulfate) - adrenal androgen, elevated DHEA-S suggests adrenal androgen excess vs ovarian source, helpful differentiating PCOS from adrenal disorders; AMH (anti-Müllerian hormone) - gold standard ovarian reserve marker, produced by small follicles in ovaries, directly correlates with remaining egg supply, levels <1.0 ng/mL indicate low reserve, <0.5 ng/mL severely diminished, undetectable AMH suggests menopause imminent, unlike FSH/estradiol AMH does not fluctuate with menstrual cycle providing stable reserve assessment. Panel identifies: PCOS (high LH:FSH ratio, high testosterone/DHEA-S, low SHBG, anovulation), diminished ovarian reserve (high FSH, low AMH, high Day 3 estradiol), hypothalamic amenorrhea (low all hormones from stress/low weight/overexercise), hyperprolactinemia (high prolactin), thyroid dysfunction (abnormal TSH), luteal phase defect (low progesterone). Results guide: fertility treatment planning (AMH/FSH predict IVF response), PCOS management (metformin, spironolactone, OCP), ovulation induction (clomiphene, letrozole if anovulatory), progesterone supplementation (luteal phase support), thyroid treatment, prolactinoma investigation. Recommended: baseline fertility assessment late 30s/early 40s, investigating irregular cycles/infertility, every 6-12 months monitoring PCOS, annually perimenopause transition. GOÄ pricing €248.03. Most comprehensive female hormone panel available.
€248.03
Schilddrüsen-Funktion (Comprehensive Thyroid Function Panel)
Complete thyroid function assessment analyzing 6 biomarkers for hypothyroidism, hyperthyroidism, autoimmune thyroid disease (Hashimoto, Graves), and thyroid hormone resistance. Venous blood sample, no fasting required though morning collection preferred. Results within 2-3 days. Essential for: fatigue, weight changes, temperature sensitivity, mood disorders, hair loss, palpitations, tremor, anxiety, irregular periods, infertility, family history thyroid disease, monitoring thyroid medication. Thyroid disease affects 12% population, especially women. Biomarkers tested: TSH (thyroid stimulating hormone) - pituitary hormone regulating thyroid, most sensitive screening test, elevated TSH (>4-5 mIU/L) indicates hypothyroidism (thyroid underactive, not producing enough hormone so pituitary increases TSH), low TSH (<0.4 mIU/L) indicates hyperthyroidism (thyroid overactive, producing excess hormone so pituitary suppresses TSH), normal range 0.4-4.0 but optimal 1.0-2.5 mIU/L for symptom relief; Free T3 (triiodothyronine) - active thyroid hormone, T3 is 3-4x more potent than T4, ~20% produced directly by thyroid, ~80% converted from T4 in peripheral tissues (liver, kidney), low Free T3 despite normal TSH/T4 suggests conversion problems (stress, inflammation, nutrient deficiency, medications, liver/kidney disease), elevated T3 in hyperthyroidism causes rapid heart rate, weight loss, anxiety, tremor; Free T4 (thyroxine) - main thyroid hormone secreted by thyroid gland, converted to active T3 in tissues, low T4 with high TSH confirms primary hypothyroidism (thyroid gland failure), low T4 with low/normal TSH suggests central hypothyroidism (pituitary/hypothalamic dysfunction rare), elevated T4 indicates hyperthyroidism; TPO Antibodies (thyroid peroxidase antibodies) - autoantibodies attacking thyroid enzyme, positive TPO antibodies (>35 IU/mL) diagnostic for Hashimoto thyroiditis (autoimmune hypothyroidism, most common cause of hypothyroidism, progressive thyroid destruction), presence predicts future hypothyroidism even if currently euthyroid, associated with infertility, miscarriage; Thyroglobulin Antibodies (TG antibodies) - autoantibodies against thyroglobulin protein, elevated in Hashimoto thyroiditis (often alongside TPO antibodies), less specific than TPO but additive diagnostic value, can interfere with thyroglobulin tumor marker measurement in thyroid cancer follow-up; TSH-Receptor Antibodies (TRAK/TRAb) - autoantibodies stimulating TSH receptor causing unregulated thyroid hormone production, positive TRAK diagnostic for Graves disease (autoimmune hyperthyroidism, most common cause hyperthyroidism), levels correlate with disease activity and relapse risk, differentiate Graves from other hyperthyroidism causes (toxic nodular goiter, thyroiditis). Panel comprehensively evaluates: primary hypothyroidism (high TSH, low T4, often positive TPO/TG antibodies from Hashimoto), subclinical hypothyroidism (high TSH, normal T4, may benefit treatment if symptomatic or antibody-positive), hyperthyroidism (low TSH, high T4/T3, TRAK positive suggests Graves), autoimmune thyroid disease (positive antibodies guide treatment/monitoring), conversion problems (normal TSH/T4 but low T3 from selenium deficiency, inflammation, medications). Results guide: levothyroxine therapy initiation/dose adjustment (hypothyroidism target TSH 1-2.5), antithyroid medication (methimazole, PTU for hyperthyroidism), radioactive iodine or surgery consideration (Graves disease), selenium supplementation (reduces antibodies in Hashimoto), monitoring antibody-positive patients for progression. Complete panel superior to TSH-only screening revealing conversion issues, autoimmunity, differentiating hyper/hypothyroidism causes. Recommended: baseline if symptoms, annually with thyroid disease/positive antibodies, 6-8 weeks after medication changes. GOÄ pricing €147.47.
€147.47