Schilddrüsen-Funktion (Comprehensive Thyroid Function Panel)

Complete thyroid function assessment analyzing 6 biomarkers for hypothyroidism, hyperthyroidism, autoimmune thyroid disease (Hashimoto, Graves), and thyroid hormone resistance. Venous blood sample, no fasting required though morning collection preferred. Results within 2-3 days. Essential for: fatigue, weight changes, temperature sensitivity, mood disorders, hair loss, palpitations, tremor, anxiety, irregular periods, infertility, family history thyroid disease, monitoring thyroid medication. Thyroid disease affects 12% population, especially women. Biomarkers tested: TSH (thyroid stimulating hormone) - pituitary hormone regulating thyroid, most sensitive screening test, elevated TSH (>4-5 mIU/L) indicates hypothyroidism (thyroid underactive, not producing enough hormone so pituitary increases TSH), low TSH (<0.4 mIU/L) indicates hyperthyroidism (thyroid overactive, producing excess hormone so pituitary suppresses TSH), normal range 0.4-4.0 but optimal 1.0-2.5 mIU/L for symptom relief; Free T3 (triiodothyronine) - active thyroid hormone, T3 is 3-4x more potent than T4, ~20% produced directly by thyroid, ~80% converted from T4 in peripheral tissues (liver, kidney), low Free T3 despite normal TSH/T4 suggests conversion problems (stress, inflammation, nutrient deficiency, medications, liver/kidney disease), elevated T3 in hyperthyroidism causes rapid heart rate, weight loss, anxiety, tremor; Free T4 (thyroxine) - main thyroid hormone secreted by thyroid gland, converted to active T3 in tissues, low T4 with high TSH confirms primary hypothyroidism (thyroid gland failure), low T4 with low/normal TSH suggests central hypothyroidism (pituitary/hypothalamic dysfunction rare), elevated T4 indicates hyperthyroidism; TPO Antibodies (thyroid peroxidase antibodies) - autoantibodies attacking thyroid enzyme, positive TPO antibodies (>35 IU/mL) diagnostic for Hashimoto thyroiditis (autoimmune hypothyroidism, most common cause of hypothyroidism, progressive thyroid destruction), presence predicts future hypothyroidism even if currently euthyroid, associated with infertility, miscarriage; Thyroglobulin Antibodies (TG antibodies) - autoantibodies against thyroglobulin protein, elevated in Hashimoto thyroiditis (often alongside TPO antibodies), less specific than TPO but additive diagnostic value, can interfere with thyroglobulin tumor marker measurement in thyroid cancer follow-up; TSH-Receptor Antibodies (TRAK/TRAb) - autoantibodies stimulating TSH receptor causing unregulated thyroid hormone production, positive TRAK diagnostic for Graves disease (autoimmune hyperthyroidism, most common cause hyperthyroidism), levels correlate with disease activity and relapse risk, differentiate Graves from other hyperthyroidism causes (toxic nodular goiter, thyroiditis). Panel comprehensively evaluates: primary hypothyroidism (high TSH, low T4, often positive TPO/TG antibodies from Hashimoto), subclinical hypothyroidism (high TSH, normal T4, may benefit treatment if symptomatic or antibody-positive), hyperthyroidism (low TSH, high T4/T3, TRAK positive suggests Graves), autoimmune thyroid disease (positive antibodies guide treatment/monitoring), conversion problems (normal TSH/T4 but low T3 from selenium deficiency, inflammation, medications). Results guide: levothyroxine therapy initiation/dose adjustment (hypothyroidism target TSH 1-2.5), antithyroid medication (methimazole, PTU for hyperthyroidism), radioactive iodine or surgery consideration (Graves disease), selenium supplementation (reduces antibodies in Hashimoto), monitoring antibody-positive patients for progression. Complete panel superior to TSH-only screening revealing conversion issues, autoimmunity, differentiating hyper/hypothyroidism causes. Recommended: baseline if symptoms, annually with thyroid disease/positive antibodies, 6-8 weeks after medication changes. GOÄ pricing €147.47.

A thyroid panel evaluates how well your thyroid gland is functioning by measuring the hormones it produces and the pituitary signal that controls it. The thyroid is a butterfly-shaped gland in your neck that regulates metabolism, energy, body temperature, heart rate, and mood. A basic panel measures TSH (the brain's signal to the thyroid) and Free T4 (the main thyroid hormone). Comprehensive panels add Free T3 (the active hormone), reverse T3, and thyroid antibodies (TPOAb, TGAb) that can detect autoimmune conditions like Hashimoto's thyroiditis or Graves' disease. Thyroid dysfunction is extremely common — affecting roughly 1 in 8 women — and often goes undiagnosed because symptoms mimic stress, aging, or depression.