Comprehensive female reproductive hormone panel for women of childbearing age analyzing 10 hormones regulating menstrual cycles, fertility, ovulation, mood, metabolic health, and ovarian reserve. Venous blood sample with critical timing - ideally Day 3-5 of menstrual cycle for FSH/LH/estradiol/AMH (early follicular phase), Day 21 for progesterone (mid-luteal phase, or 7 days before expected period). Results within 3-5 days. Essential for: irregular periods, fertility issues, PCOS investigation, unexplained weight gain, mood disorders, low libido, PMS symptoms, perimenopause concerns, assessing ovarian reserve before fertility treatment. Biomarkers tested: FSH (follicle-stimulating hormone) - controls ovarian follicle maturation and egg development, Day 3 FSH levels predict ovarian reserve (low reserve if FSH >10-15 IU/L, approaching menopause if >25 IU/L), very high FSH (>40 IU/L) indicates ovarian failure/menopause, cyclic FSH rises select dominant follicle for ovulation; LH (luteinizing hormone) - triggers ovulation mid-cycle releasing mature egg, LH:FSH ratio diagnostic for PCOS (ratio >2:1 suggests PCOS with multiple small follicles and anovulation), absent LH surge indicates anovulation (no ovulation occurring); Estradiol (E2) - primary estrogen hormone, regulates menstrual cycle, maintains endometrium, bone density, cardiovascular health, brain function, libido, skin/hair quality, Day 3 levels should be low (<50-80 pg/mL for normal ovarian function, elevated Day 3 estradiol suggests diminished ovarian reserve or ovarian cyst), rises during follicular phase peaking just before ovulation, low estradiol causes irregular periods, hot flashes, vaginal dryness, bone loss; Progesterone - produced by corpus luteum after ovulation, maintains early pregnancy, balances estrogen, thickens endometrium for implantation, Day 21 progesterone confirms ovulation occurred (levels >10 ng/mL indicate ovulation, <10 ng/mL suggest anovulation or luteal phase defect causing infertility/miscarriage), low progesterone causes irregular bleeding, PMS, anxiety, insomnia; Testosterone - androgen affecting libido, energy, muscle mass, mood in women, mildly elevated testosterone common in PCOS (along with high LH:FSH ratio), very high testosterone suggests other androgen excess disorders; SHBG (sex hormone-binding globulin) - binds testosterone and estrogen, low SHBG (from insulin resistance, obesity, PCOS) increases free androgens worsening PCOS symptoms (acne, hirsutism, hair loss); Prolactin - elevated prolactin (>25 ng/mL) suppresses GnRH release causing anovulation, irregular periods, infertility, galactorrhea, caused by prolactinoma, medications, hypothyroidism, stress; TSH (thyroid stimulating hormone) - thyroid dysfunction causes menstrual irregularities, anovulation, infertility, both hypothyroidism (irregular heavy periods, weight gain) and hyperthyroidism (light/absent periods, weight loss) disrupt reproduction; DHEA-S (dehydroepiandrosterone sulfate) - adrenal androgen, elevated DHEA-S suggests adrenal androgen excess vs ovarian source, helpful differentiating PCOS from adrenal disorders; AMH (anti-Müllerian hormone) - gold standard ovarian reserve marker, produced by small follicles in ovaries, directly correlates with remaining egg supply, levels <1.0 ng/mL indicate low reserve, <0.5 ng/mL severely diminished, undetectable AMH suggests menopause imminent, unlike FSH/estradiol AMH does not fluctuate with menstrual cycle providing stable reserve assessment. Panel identifies: PCOS (high LH:FSH ratio, high testosterone/DHEA-S, low SHBG, anovulation), diminished ovarian reserve (high FSH, low AMH, high Day 3 estradiol), hypothalamic amenorrhea (low all hormones from stress/low weight/overexercise), hyperprolactinemia (high prolactin), thyroid dysfunction (abnormal TSH), luteal phase defect (low progesterone). Results guide: fertility treatment planning (AMH/FSH predict IVF response), PCOS management (metformin, spironolactone, OCP), ovulation induction (clomiphene, letrozole if anovulatory), progesterone supplementation (luteal phase support), thyroid treatment, prolactinoma investigation. Recommended: baseline fertility assessment late 30s/early 40s, investigating irregular cycles/infertility, every 6-12 months monitoring PCOS, annually perimenopause transition. GOÄ pricing €248.03. Most comprehensive female hormone panel available.
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Basis-Check (Basic Health Screening)
Comprehensive basic health screening analyzing 18 biomarkers for cardiovascular, metabolic, liver, kidney, and thyroid function. Venous blood sample with 12-hour fasting required for accurate glucose and lipid measurements. Results typically same-day or within 24 hours via patient portal. Appointment booking via Doctolib, blood sampling Monday-Friday (9:00-17:00, Wednesday until 18:00). GOÄ fee schedule pricing. Essential annual health check covering all major organ systems for disease prevention and early detection. Biomarkers tested: Blood Count - complete blood count (CBC) with differential detecting anemia, infection, inflammation, immune disorders including RBC, WBC, hemoglobin, hematocrit, platelets, neutrophils, lymphocytes, monocytes, eosinophils, basophils; Metabolism - fasting glucose (diabetes screening), HbA1c (glycated hemoglobin reflecting 2-3 month glucose average, gold standard diabetes marker), uric acid (gout risk, kidney function); Cardiovascular - total cholesterol, HDL cholesterol ("good"), LDL cholesterol ("bad"), triglycerides (fat metabolism, cardiovascular risk); Liver - GPT/ALAT (liver inflammation, cell damage), GOT/ASAT (liver and heart damage), bilirubin (bile flow, liver function, hemolysis), alkaline phosphatase (liver and bone enzyme); Kidney - creatinine (filtration capacity), urea (protein metabolism, kidney function); Electrolytes - sodium (fluid balance, blood pressure), potassium (heart rhythm, nerve/muscle function), calcium (bone health, nerve transmission, muscle contraction). Comprehensive panel efficiently screens for: diabetes/prediabetes, cardiovascular disease risk, liver disease (hepatitis, fatty liver, alcohol damage), kidney dysfunction, anemia, electrolyte imbalances, metabolic syndrome. Ideal for annual health monitoring, establishing health baseline, or investigating non-specific symptoms (fatigue, weakness). Price €63.66 includes blood draw (€4.20) and all analyses.
Herz-Kreislauf-Check (Cardiovascular Risk Assessment)
Advanced cardiovascular risk screening analyzing 10 biomarkers for heart attack, stroke, and atherosclerosis risk assessment. Venous blood sample with 12-hour fasting required. Same-day results available. Essential for: family history of heart disease, over age 40, smokers, diabetes, hypertension, high cholesterol, obesity, sedentary lifestyle. Identifies modifiable risk factors before cardiovascular events occur. Biomarkers tested: Lipid Panel - total cholesterol (overall risk), HDL cholesterol ("good" protective cholesterol, target >40 mg/dL men, >50 mg/dL women), LDL cholesterol ("bad" cholesterol causing arterial plaque, target <100 mg/dL, <70 mg/dL high-risk patients), triglycerides (fat metabolism, independent risk factor when elevated); Advanced Cardiovascular Markers - lipoprotein(a) [Lp(a)] (genetic cardiovascular risk factor unaffected by lifestyle, strong predictor of heart attack/stroke even with normal cholesterol, elevated levels >30 mg/dL require aggressive LDL management), homocysteine (amino acid, elevated levels (>15 µmol/L) damage arterial walls promoting atherosclerosis, linked to B vitamin deficiency); Blood Count - complete blood count (anemia affects oxygen delivery to heart, polycythemia increases blood viscosity and clot risk); Metabolism - fasting glucose (diabetes damages vessels accelerating atherosclerosis), HbA1c (long-term glucose control, diabetes/prediabetes screening); Kidney - creatinine (kidney disease accelerates cardiovascular disease). Panel provides comprehensive cardiovascular risk stratification beyond basic cholesterol testing. Lp(a) testing particularly valuable as this genetic risk factor often overlooked in standard screening but affects 20% of population. Homocysteine identifies treatable risk factor (lowered with B vitamins). Results guide: statin therapy initiation, aspirin therapy, blood pressure management, diabetes treatment, lifestyle modifications (diet, exercise, smoking cessation). Recommended frequency: baseline age 40, annually if high risk, every 3-5 years if low risk. GOÄ pricing €93.16.
Diabetes Mellitus Screening
Focused diabetes screening panel analyzing 2 key glucose biomarkers for diabetes diagnosis and monitoring. Venous blood sample with 12-hour fasting required for accurate fasting glucose measurement. Results within 24 hours. Essential for: family history of diabetes, overweight/obesity (BMI >25), sedentary lifestyle, history of gestational diabetes, prediabetes diagnosis, unexplained fatigue/thirst/urination. American Diabetes Association and German guidelines recommend screening every 3 years for adults over 45, annually if risk factors present. Biomarkers tested: Fasting Glucose - blood sugar after overnight fast, diagnostic criteria: <100 mg/dL normal, 100-125 mg/dL prediabetes, ≥126 mg/dL diabetes (requires confirmation), detects current glycemic control but only snapshot of one moment; HbA1c (Glycated Hemoglobin) - percentage of hemoglobin with attached glucose, reflects average blood sugar over past 2-3 months (lifespan of red blood cells), diagnostic criteria: <5.7% normal, 5.7-6.4% prediabetes, ≥6.5% diabetes, gold standard for diabetes diagnosis and monitoring, not affected by recent meals or daily fluctuations, correlates directly with diabetes complications risk (every 1% increase in HbA1c increases microvascular complications ~30%). Panel advantages: fasting glucose detects current dysglycemia, HbA1c confirms chronic hyperglycemia and tracks long-term control, combination improves diagnostic sensitivity. Early diabetes detection enables: lifestyle interventions preventing progression (weight loss, exercise, diet), metformin therapy for prediabetes, avoiding complications (neuropathy, retinopathy, nephropathy, cardiovascular disease). For diagnosed diabetics, panel monitors treatment effectiveness (target HbA1c <7% for most, <6.5% for some, individualized). Cost-effective focused screening €16.09, can be added to any package. Recommended frequency: prediabetes every 3-6 months, established diabetes every 3 months. GOÄ pricing.
Sport Check-up (Athletic Performance & Recovery Panel)
Comprehensive athletic performance optimization panel analyzing 20+ biomarkers for energy production, muscle function, recovery capacity, and nutritional adequacy. Venous blood sample, fasting recommended. Results within 2-3 days. Essential for: competitive athletes, endurance training, strength training, masters athletes, performance plateaus, slow recovery, recurring injuries, fatigue despite training. Identifies limiting factors preventing optimal performance and adaptation. Biomarkers tested: Blood Count - complete CBC detecting sports anemia (dilutional or iron deficiency), overtraining syndrome (altered WBC differential), adequate oxygen carrying capacity (hemoglobin/hematocrit); Energy Metabolism - glucose (fuel availability), lipid panel (total cholesterol, HDL, LDL, triglycerides - athletes should have optimal lipids despite high caloric intake, abnormal values suggest metabolic dysfunction or dietary issues); Liver - liver enzymes (GPT, GOT, elevated with overtraining or muscle damage, chronically high suggests inadequate recovery); Kidney - creatinine (filtration, muscle breakdown marker especially in strength athletes); Inflammation - CRP (C-reactive protein, acute training stress increases CRP, chronically elevated suggests inadequate recovery or overtraining); Thyroid - TSH (thyroid stimulating hormone, hypothyroidism causes fatigue, weight gain, poor performance, common in athletes especially female with low energy availability/RED-S); Minerals Essential for Performance - magnesium (muscle contraction, energy production, 300+ enzymatic reactions, deficiency causes cramps, fatigue, impaired recovery), calcium (muscle contraction, bone health, neurotransmission), zinc (immune function, testosterone production, wound healing, taste/appetite - low in athletes from sweat losses), selenium (antioxidant, immune function, thyroid conversion); Iron Status - ferritin (iron stores, most sensitive marker of iron deficiency before anemia develops, athletes especially endurance/female at high risk from increased needs, GI losses, foot strike hemolysis, low ferritin causes fatigue, reduced endurance, impaired adaptation to training); Vitamins - vitamin D (bone health, immune function, muscle function, testosterone production, 40-60% athletes deficient especially winter/indoor sports, optimal levels 40-60 ng/mL for performance), amino acids (building blocks for muscle protein synthesis, recovery, neurotransmitter production, imbalances suggest inadequate protein intake or absorption). Panel provides: nutritional deficiency identification (correct before supplementing), overtraining detection (elevated CRP, altered hormones/blood counts), thyroid dysfunction screening (common in athletes), iron status assessment (prevent/treat sports anemia), metabolic health verification. Results guide: targeted supplementation (iron, vitamin D, magnesium based on actual deficiency), training load adjustment (reduce if inflammatory markers high), nutrition optimization (adequate protein, micronutrients), injury risk reduction. Recommended: baseline before training season, every 6 months during heavy training, when performance plateaus or declines unexpectedly. GOÄ pricing €188.34.