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IFCOR laboratory technician performing sample analysis with pipette
Two IFCOR scientists reviewing samples at microscope
IFCOR laboratory technician with pipette — close-up

Thrombophilia Genetic Panel

Type

Blood Testing

Duration

20 min

Results

14 days

Sample

Blood (venous draw)

What's included

6 deliverables in this treatment

  • Coagulation function: CBC, prothrombin time (INR), aPTT, fibrinogen, D-dimers, antithrombin III
  • Molecular PCR genetics: Factor V Leiden, Prothrombin G20210A, Factor XIII V34L
  • MTHFR C677T and MTHFR A1298C gene variants
  • PAI-1 4G/5G polymorphism — fibrinolysis capacity
  • Informed consent process included
  • Results within 2 weeks by secure communication

IFCOR's Thrombophilia Genetic Panel is a comprehensive coagulation and genetics screen for people at elevated risk of inherited blood-clotting disorders. It combines haematological coagulation markers (CBC, prothrombin time, aPTT, fibrinogen, D-dimers, antithrombin) with molecular PCR testing for the five most clinically significant thrombophilia mutations: Factor V Leiden, Prothrombin gene G20210A, Factor XIII, MTHFR C677T, MTHFR A1298C, and PAI-1 4G/5G. Unlike coagulation function tests alone, genetic testing identifies permanent inherited risk that does not normalise with treatment — enabling lifelong risk-aware decisions about anticoagulation, hormonal contraception, pregnancy management, and surgery. Informed consent is required. Results are available within two weeks.

About this treatment

Thrombophilia — a hereditary or acquired tendency toward abnormal blood clotting — is an important predisposing factor for deep vein thrombosis, pulmonary embolism, stroke, recurrent miscarriage, and placental insufficiency. IFCOR's comprehensive panel tests both the functional coagulation system and the genetic variants most strongly associated with inherited thrombophilia risk. The functional coagulation markers included are: CBC for platelet count and…

Good to know

Panel type
Coagulation function + 6 genetic variants
Genetic consent
Required — informed consent process included
Turnaround
Within 2 weeks
Accreditation
ISO 15189:2013 (ČIA M 8106)

Who is this for?

People with a family or personal history of DVT, pulmonary embolism, or recurrent miscarriage; women before starting hormonal contraception; anyone being assessed for surgery anticoagulation planning.

Preparation required

Fasting not required. Signed informed consent required before sample collection. Inform staff of all anticoagulation medications — some may affect the functional coagulation results.

About the clinic

Reviews, team and credentials

Independent review links and clinic-reported team information.

Clinical team

IFCOR was founded and is led by RNDr. František Flek, who established the original allergy and immunology laboratory in 1994. The network holds ISO 15189:2013 accreditation across five facilities (ČIA number M 8106) and participates in four external quality assurance programmes: SEKK, EHK SZÚ Prague, Instand, and ÚHKT. The Jihlava laboratory team covers nine specialist disciplines — clinical biochemistry,…

Clinic-reported credentials

ISO 15189:2013 (ČIA M 8106) SÚKL diagnostic laboratory permit SZÚ sterilizer control authorisation SEKK external quality assurance EHK SZÚ Prague external quality assurance Instand external quality assurance ÚHKT external quality assurance

Languages: Czech

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