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MUDr. Anežka Vochtová

HArmonyCA — Hybrid Biostimulating Injectable

Type

Botox & Fillers

Duration

45 min

What's included

4 deliverables in this treatment

  • Emla topical anaesthetic application
  • Skin cleansing and disinfection
  • HArmonyCA hybrid injectable via cannula
  • Cold compresses for post-injection comfort

HArmonyCA is a next-generation hybrid injectable that combines two active substances in a single syringe: hyaluronic acid for immediate volumising and lifting, and calcium hydroxyapatite (CaHA) microspheres for longer-term collagen biostimulation. The HA component provides instant soft tissue augmentation and skin hydration, while the CaHA particles act as a scaffold that stimulates the body's own fibroblasts to produce new collagen, progressively firming the treated area over 12 weeks. At AV Aesthetics, HArmonyCA is delivered via cannula after Emla topical anaesthetic is applied, and is used for facial firming, structural lifting, rejuvenation, and overall skin quality improvement. Results become fully visible after approximately 12 weeks and typically last 19 months or longer.

About this treatment

HArmonyCA (manufactured by Galderma) represents a specific category of injectable product known as a hybrid or combination biostimulator — distinct from standard HA fillers in that it does not simply add volume, but actively promotes the body's own collagen synthesis for a progressive, firming result.

The two-component mechanism works in sequence. The hyaluronic acid phase acts immediately on injection: it integrates into the intercellular matrix, drawing water and providing lift, firmness, and hydration in the treated zone. This immediate effect is similar to a conventional HA filler. The calcium hydroxyapatite phase works more slowly: the CaHA microspheres are too large to be metabolised quickly, and they act as a physical scaffold around which…

The clinical consequence of this dual mechanism is that the result continues to improve for up to 12 weeks after injection, and then persists significantly longer than a standard HA filler — studies of CaHA-based products report durability of 19 months or more for the full treatment effect.

Good to know

Product
HArmonyCA (Galderma) — HA + CaHA
Delivery
Cannula (lower bruising risk)
Full result
After 12 weeks
Duration
19+ months

Who is this for?

Facial firming, structural lifting, soft tissue augmentation, skin hydration, overall rejuvenation in patients wanting collagen stimulation alongside immediate volume

Preparation required

No active skin conditions in the treatment area for at least one week before appointment. Avoid aspirin, Warfarin, and other blood-thinning medications on the day of treatment.

About the clinic

Reviews, team and credentials

Independent review links and clinic-reported team information.

AV Aesthetics clinical team

Clinical team

MUDr. Anežka Vochtová holds a medical degree from Palacký University Olomouc. She previously worked in the Ophthalmology Department at Municipal Hospital Ostrava, and concurrently at Oční EU Vratimov and LE clinic in Frýdlant nad Ostravicí. She began specialising in aesthetic medicine in 2018, holding multiple certifications in injectable and energy-based treatments. She performs every procedure personally and…

Languages: cs

What clients say

"{"author":"Kateřina","text":"I have had both Botox and three PRP plasma therapies at AV Aesthetics. Dr Vochtová explained everything patiently and recommended treatments tailored to me. AV Aesthetics is the place that advises you and professionally delivers a touch of perfection. 100%..."

"{"author":"Valentina","text":"I am more than satisfied with Dr Vochtová's work. I was afraid it would be painful, but it wasn't — the injection was barely felt. I would definitely recommend AV Aesthetics.","source":"avaesthetics.cz"}"

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