YEARS Ultimate®

Ultimate longevity diagnostic program with 230 lab biomarkers, 25+ functional examinations, whole-body MRI, multi-cancer detection, genomics, microbiomics, and epigenomics. Blood, urine, stool, saliva, living cell samples. Most comprehensive longevity program combining ALL diagnostic modalities. Biomarkers tested: ALL YEARS Evolve® biomarkers (120 markers) PLUS: Autoimmune Markers - ANA (antinuclear antibodies), RF (rheumatoid factor), anti-CCP, anti-TPO (thyroid peroxidase), anti-thyroglobulin, celiac disease markers (anti-tTG, anti-DGP); Infection Screening - Hepatitis B (HBsAg, anti-HBs, anti-HBc), Hepatitis C (anti-HCV), HIV (antibody/antigen test), EBV (Epstein-Barr virus), CMV (cytomegalovirus); Advanced Cytokines - TNF-alpha (tumor necrosis factor), IL-1beta, IL-8, IL-10, interferon-gamma; Oxidative Stress - TMAO (trimethylamine N-oxide), CoQ10 (coenzyme Q10), glutathione, 8-OHdG (DNA damage marker), malondialdehyde (MDA); Immunoglobulins - IgG subclasses (IgG1, IgG2, IgG3, IgG4), IgA, IgM, IgE; Amino Acids - essential amino acids profile (leucine, isoleucine, valine, lysine, methionine, phenylalanine, threonine, tryptophan), non-essential amino acids (arginine, glutamine, glycine, proline, tyrosine); Advanced Nutrients - Nicotinamide (NAD+ precursor), Vitamin B1 (thiamine), B2 (riboflavin), B6 (pyridoxine), B9 (folate), biotin, pantothenic acid; Heavy Metals - lead, mercury, cadmium, arsenic; Bone Health - osteocalcin, CTX (bone turnover marker), vitamin K status. Advanced Diagnostics: Medical Genomics - whole exome/genome sequencing analyzing 170+ disease risk genes (cancer susceptibility, cardiovascular disease, Alzheimer's, metabolic disorders), 150+ pharmacogenomics markers (drug metabolism, adverse reaction risks); Microbiomics - comprehensive gut bacteria and fungi analysis, diversity scores, pathogen detection, dysbiosis markers; Epigenomics - biological age assessment via DNA methylation patterns, epigenetic aging clocks, age acceleration metrics; YEARS Performance Battery - advanced functional testing; Biological Specimen Preservation - cryopreservation of 70 blood samples for future regenerative medicine applications. Premium Support: Year-round concierge support with 10-hour annual retainer; 3 physician check-ins annually; Monthly coaching sessions (nutrition, performance, lifestyle). Most advanced longevity program globally for comprehensive health optimization, disease prevention, and lifespan extension.

This comprehensive health screening package combines blood tests, clinical assessments, and specialist consultations tailored to your age, sex, and health goals. Packages typically include a full blood panel (metabolic markers, organ function, complete blood count), vital signs, and may include imaging, cardiac assessment, or cancer screening depending on the tier. These curated programs are designed to provide a thorough health evaluation in a single visit, making them ideal for annual checkups, executive health reviews, or anyone wanting a structured, all-in-one health assessment. Results come with a detailed report and doctor consultation to interpret findings and plan next steps.