NAD+ IV Drip 250mg

A 250-milligram intravenous infusion of nicotinamide adenine dinucleotide (NAD+), administered slowly over approximately two hours. NAD+ is a coenzyme present in every living cell that plays a central role in cellular energy production, DNA repair, and sirtuin activation.

Wellth's NAD+ IV Drip delivers 250 milligrams of nicotinamide adenine dinucleotide directly into the bloodstream over a two-hour infusion window. The slow drip rate is deliberate — NAD+ infusions administered too rapidly can produce temporary side effects including chest tightness, nausea, and flushing, so the clinic titrates the flow to maintain patient comfort throughout the session. NAD+ is a coenzyme that participates in over 500 enzymatic reactions in human cells. Its most well-characterised role is as an electron carrier in the mitochondrial electron transport chain, where it shuttles electrons from the citric acid cycle to complex I, driving the proton gradient that powers ATP synthesis. Without adequate NAD+, mitochondrial energy production declines, and cells shift toward less efficient metabolic pathways. Beyond energy metabolism, NAD+ is consumed as a substrate by three families of enzymes with distinct biological functions. Sirtuins (SIRT1-7) use NAD+ to deacetylate proteins involved in DNA repair, inflammatory regulation, circadian rhythm maintenance, and metabolic adaptation. PARPs (poly-ADP-ribose polymerases) use NAD+ to repair single-strand DNA breaks, a process that becomes increasingly active with age and cumulative DNA damage. CD38, an NAD+ glycohydrolase, consumes NAD+ as part of calcium signalling and immune cell function. Intracellular NAD+ levels decline measurably with age — studies suggest a roughly 50 percent reduction between the ages of 40 and 60 in some tissues. This decline is driven by increased consumption (more DNA damage to repair, higher inflammatory signalling) and reduced synthesis. While oral precursors such as NMN and NR can support NAD+ biosynthesis, intravenous delivery provides a more direct elevation of circulating NAD+ levels. At Wellth, the infusion is administered in a comfortable reclining setting with a nurse monitoring the drip rate and checking in at regular intervals. Patients are encouraged to bring reading material or work, as the two-hour session requires relatively little active participation. Mild flushing or warmth during the infusion is normal and typically resolves by slowing the drip rate briefly.