PRP and PRF Injections

Platelet-rich plasma (PRP) and platelet-rich fibrin (PRF) injectable treatments at UnionDerm, listed under the clinic's Injectables category. Both use a patient's own blood, processed by centrifuge to concentrate growth factors, and re-injected to stimulate collagen production, skin rejuvenation, and healing. Performed by board-certified dermatologists at the Union Square clinic. Complementary to filler and laser treatments.

Union Square Laser Dermatology offers platelet-rich plasma (PRP) and platelet-rich fibrin (PRF) injectable treatments as part of its comprehensive injectables program, performed exclusively by board-certified dermatologists. Both PRP and PRF are autologous blood-derived treatments — meaning they use the patient's own blood — which eliminates the risk of allergic reaction or immunological rejection. The process begins with a standard blood draw, after which the sample is centrifuged to separate blood components by density. For PRP, the centrifugation produces a plasma fraction highly concentrated in platelets (typically 3–8 times baseline concentration); platelets are alpha-granule storage vesicles for a rich array of growth factors including platelet-derived growth factor (PDGF), transforming growth factor-beta (TGF-β), vascular endothelial growth factor (VEGF), insulin-like growth factor-1 (IGF-1), and epidermal growth factor (EGF). When injected into the dermis or periosteal tissues, activated platelets release these growth factors, stimulating fibroblast proliferation, collagen and elastin synthesis, angiogenesis, and local tissue repair and regeneration. PRF (platelet-rich fibrin) uses a slower centrifugation protocol without anticoagulant additives, producing a fibrin matrix that traps platelets and leukocytes in a three-dimensional scaffold; growth factor release from PRF is slower and more sustained than from PRP (days to weeks versus hours), which some practitioners prefer for certain collagen-stimulation applications. At UnionDerm, PRP and PRF are used for facial skin rejuvenation (improved texture, tone, and fine lines), under-eye hollowing, and as adjuncts to other treatments including microneedling and laser procedures to enhance and accelerate healing. The clinic also offers FoLix, the first FDA-cleared fractional laser specifically for hair loss, as a complementary or alternative option for patients seeking hair restoration without injectable growth factor approaches. New patient consultations at $400 are required; $200 appointment deposits are standard.