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Celiac Disease Genetic Test (HLA-DQ2/DQ8)

Type

Blood Testing

Duration

15 min

Results

10 days

Sample

Blood (venous)

What's included

4 deliverables in this treatment

  • HLA-DQ2 and HLA-DQ8 allele typing from a venous blood sample
  • Specialist physician interpretation report included in the price (via uLékaře.cz)
  • Result unaffected by current diet (gluten-free or not)
  • Digital results within 10 business days

A genetic blood test for the HLA-DQ2 and HLA-DQ8 alleles determining genetic susceptibility to celiac disease — the most common gastrointestinal autoimmune condition in Europe, affecting approximately 1% of the population but with over 80% of cases estimated to remain undiagnosed. Available at 2,052 Kč including specialist interpretation through cz.unilabs.online. Unlike standard serological celiac tests (which only turn positive after gluten exposure has already caused intestinal damage), the genetic test identifies lifelong susceptibility before or without gluten ingestion — and is unaffected by current diet. Results in 10 business days. Rated 4.86/5 across 63 reviews.

About this treatment

Celiac disease is an autoimmune condition triggered by dietary gluten in genetically predisposed individuals. The HLA genetic variants DQ2 and DQ8 on chromosome 6 are necessary for the development of celiac disease: approximately 95% of celiac patients carry HLA-DQ2, and most of the remainder carry HLA-DQ8. People who carry neither variant have a near-zero lifetime risk of developing celiac disease, regardless of gluten exposure.

This genetic test is particularly valuable in three scenarios:

Gluten-free diet already in progress: Standard serological tests (anti-TTG IgA, anti-gliadin antibodies) turn negative after several months on a strict gluten-free diet. The HLA genetic test is not affected by diet — it reflects inherited genotype.

Good to know

Price
2,052 Kč incl. interpretation
Tests
HLA-DQ2 and HLA-DQ8 allele typing
Turnaround
10 business days
Rating
4.86/5 (63 reviews)

Who is this for?

Patients already on gluten-free diet (serology unreliable), first-degree relatives of celiac patients, equivocal serology or IgA deficiency, suspected non-coeliac gluten sensitivity

Preparation required

No fasting required. Do not change your current diet before the test — genetic results are diet-independent. Normal gluten intake is neither required nor harmful for this test.

About the clinic

Reviews, team and credentials

Independent review links and clinic-reported team information.

4.9

11,172 clinic reviews

From independent platforms

Clinical team

Unilabs Diagnostics k.s. employs over 1,450 staff across its Czech laboratory network, including board-certified specialists in clinical biochemistry, haematology, immunology, microbiology, pathology, and forensic genetics. All laboratory operations are supervised by qualified laboratory physicians under the Czech Ministry of Health's accreditation framework. Collection points are staffed by trained phlebotomists…

Languages: Czech

What clients say

"{"author":"Dušan — PSA test (verified customer, cz.unilabs.online)","text":"Bez čekání, rychle, vše OK, výsledek rychle. (No waiting, fast, everything OK, result quickly.)","rating":5}"

"{"author":"Verified customer — Thyroid EXPERT (cz.unilabs.online, June 2026)","text":"Profesionální přístup a rychlé výsledky. Oceňuji možnost objednání online bez nutnosti navštívit lékaře předem.","rating":5}"

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Kč 2,052