Type
Blood Testing
Biomarkers
1
Duration
15 min
Results
3 days
Sample
Blood (venous)
What's included
4 deliverables in this treatment
- Total PSA (prostate-specific antigen) measurement
- Free PSA measurement (free PSA fraction calculation)
- [-2]proPSA (p2PSA) isoform measurement
- Calculated PHI index combining all three values for cancer risk stratification
The Prostate Health Index (PHI) is a blood test that substantially improves the clinical accuracy of PSA-based prostate cancer screening by combining three measurements — total PSA, free PSA, and the [-2]proPSA isoform (p2PSA) — into a single calculated index. Available at 1,298 Kč through cz.unilabs.online and collected at any Prague Unilabs point, PHI is used to decide whether a prostate biopsy is genuinely necessary in men with mildly or moderately elevated PSA. A standard PSA reading in the 'grey zone' (4–10 ng/mL) leads to unnecessary biopsies in approximately 70% of cases; PHI's higher specificity reduces this substantially, sparing many men an invasive procedure. Recommended for men aged 45+. Results within 3 business days. Rated 4.58/5 across 48 reviews.
About this treatment
Prostate-specific antigen (PSA) testing has been the primary prostate cancer screening tool for decades, but its major limitation is poor specificity: PSA is elevated not only in prostate cancer but in benign prostatic hyperplasia (BPH), prostatitis, and after physical activity involving the prostate. The result is that a large proportion of men with elevated PSA in the 4–10 ng/mL range (the 'diagnostic grey zone') are referred for prostate biopsy when no…
The Prostate Health Index solves this by combining three PSA-related measurements in a validated algorithm. Total PSA provides the overall antigen level. Free PSA is the fraction of PSA circulating unbound to serum proteins: a low free PSA percentage (free PSA/total PSA ratio) is associated with higher cancer probability, while benign conditions tend to produce proportionally more free PSA. The [-2]proPSA (p2PSA) is the most cancer-specific isoform of PSA…
The PHI formula combines these three values: PHI = (p2PSA / free PSA) × √total PSA. In clinical validation studies (including the European Randomised Study of Screening for Prostate Cancer, ERSPC), PHI has demonstrated superior sensitivity for clinically significant prostate cancer compared to total PSA or %fPSA alone, while substantially reducing the biopsy rate in men who are ultimately cancer-free.
Good to know
- Parameters
- 3 measurements → PHI index
- Price
- 1,298 Kč
- Turnaround
- 3 business days
- Rating
- 4.58/5 (48 reviews)
Who is this for?
Men aged 45+ for prostate cancer risk assessment, especially those with elevated or borderline PSA who want to evaluate biopsy necessity
Preparation required
Avoid sexual intercourse, cycling, and strenuous exercise for 48 hours before the test. Postpone 2 weeks after a rectal examination or prostate massage. Wait 2 weeks after a prostate biopsy before testing.
Panel categories
Biomarkers tested
1Measures only the unbound PSA in the blood.
About the clinic
Reviews, team and credentials
Independent review links and clinic-reported team information.
11,172 clinic reviews
From independent platforms
Clinical team
Unilabs CZ employs over 1,450 staff across its laboratory network, including board-certified specialists in clinical biochemistry, haematology, immunology, microbiology, pathology, and forensic genetics. All laboratory operations are supervised by qualified laboratory physicians (atestovaní lékaři) under the Czech Ministry of Health's accreditation framework. The Prague client centre at Hadovka (Praha 6 – Evropská)…
Languages: Czech
What clients say
"{"author":"Verified customer — Prostate PHI Test (cz.unilabs.online)","text":"Profesionální přístup a rychlé výsledky. Oceňuji možnost objednání online bez nutnosti navštívit lékaře předem.","rating":4}"
"{"author":"Verified customer — Thyroid Panel (cz.unilabs.online)","text":"Vše proběhlo rychle a profesionálně. Výsledky jsem měla do 2 dnů a online interpretace mi vše srozumitelně vysvětlila.","rating":5}"
Treatment highlights
- Total PSA (prostate-specific antigen) measurement
- Free PSA measurement (free PSA fraction calculation)
+2 more items in What's included
1,298 Kč per test. Includes total PSA, free PSA, and p2PSA measurements combined into the PHI index calculation. Results within 3 business days.