Liver Function Panel

A liver function blood panel available at 390 Kč through cz.unilabs.online, covering the standard hepatic enzyme and metabolite profile in a single venous blood draw at any Prague Unilabs collection point. The liver processes every substance absorbed from the gut and is the primary site of detoxification, protein synthesis, bile production, and glycogen storage — making regular liver function testing valuable for anyone taking long-term medications, consuming alcohol regularly, managing metabolic syndrome, or simply wanting a general health baseline. The panel screens for cell damage (ALT, AST, GGT), cholestatic disease (ALP, bilirubin), and synthetic function (albumin). Results within 2 business days.

The liver function panel at Unilabs CZ measures the standard hepatic biochemistry profile used in clinical practice across Europe to screen for liver cell injury, cholestatic disease, and impaired synthetic function. The liver is one of the organs most commonly stressed by modern lifestyles — excess alcohol, non-alcoholic fatty liver disease (NAFLD, now affecting an estimated 25% of European adults), long-term medication use (statins, NSAIDs, antibiotics, hormonal contraceptives), and metabolic syndrome all generate detectable biochemical signatures in liver enzymes before symptoms or imaging changes become apparent. The core markers in the panel address three distinct liver functions: Cell damage markers: ALT (alanine aminotransferase) and AST (aspartate aminotransferase) are enzymes released from damaged hepatocytes into the bloodstream. ALT is liver-specific; elevated ALT is the most sensitive early marker for hepatocellular damage regardless of cause. AST is less specific (also elevated in muscle damage) but the AST/ALT ratio provides additional diagnostic information — an AST:ALT ratio above 2:1 is associated with alcoholic liver disease. GGT (gamma-glutamyltransferase) is elevated in both liver disease and alcohol use, making it useful as a combined hepatic and alcohol-use marker. Cholestatic markers: ALP (alkaline phosphatase) and bilirubin (total and/or direct) rise when bile flow is obstructed — whether by gallstones, bile duct disease, or intrahepatic cholestasis. Elevated bilirubin without raised ALT suggests haemolysis or Gilbert's syndrome rather than primary liver disease. Synthetic function: Albumin, produced exclusively by the liver, is a marker of synthetic reserve. Falling albumin in the context of elevated liver enzymes indicates reduced hepatic synthetic capacity — a sign of more advanced liver disease. For patients taking long-term medications with known hepatotoxicity (metformin, statins, valproate, antibiotics, antifungals, or herbal supplements), an annual liver panel is a practical monitoring tool. The Unilabs booking flow makes this accessible without a GP appointment: order online, attend a Prague collection point for a 10-minute fasting blood draw, and receive results within 2 business days.