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Celiac Disease Genetic Test (HLA-DQ2/DQ8)

Type

Blood Testing

Duration

15 min

Results

10 days

Sample

Blood (venous)

What's included

4 deliverables in this treatment

  • HLA-DQ2 and HLA-DQ8 allele typing from a venous blood sample
  • Specialist physician interpretation report included in the price (via uLékaře.cz)
  • Result unaffected by current diet (gluten-free or not)
  • Digital results within 10 business days

A genetic blood test for the HLA-DQ2 and HLA-DQ8 alleles that determine genetic susceptibility to celiac disease — the most common gastrointestinal autoimmune condition in Europe, affecting approximately 1% of the population but with over 80% of cases estimated to remain undiagnosed. Available at 2,052 Kč including specialist interpretation through cz.unilabs.online and collected at any Prague Unilabs collection point. Unlike the standard serological celiac test (IgA anti-tissue transglutaminase), which only turns positive after gluten exposure has already caused intestinal damage, the genetic test identifies lifelong susceptibility before or without gluten ingestion. Results in 10 business days. Rated 4.86/5 across 63 reviews.

About this treatment

Celiac disease is an autoimmune condition triggered by dietary gluten in genetically predisposed individuals. The HLA (human leukocyte antigen) genetic variants DQ2 and DQ8 on chromosome 6 are necessary — though not sufficient — for the development of celiac disease: approximately 95% of celiac patients carry HLA-DQ2, and most of the remainder carry HLA-DQ8. People who carry neither variant have a near-zero lifetime risk of developing celiac disease,…

This genetic test is particularly valuable in three scenarios:

Gluten-free diet already in progress: Standard serological tests (anti-TTG IgA, anti-gliadin antibodies) turn negative after several months on a strict gluten-free diet. If a patient has self-diagnosed celiac disease and started the GFD before getting tested, serology will be falsely negative and a normal biopsy will not rule out celiac disease. The HLA genetic test is not affected by diet — it reflects inherited genotype and gives a definitive result…

Good to know

Price
2,052 Kč incl. interpretation
Tests
HLA-DQ2 and HLA-DQ8 allele typing
Turnaround
10 business days
Rating
4.86/5 (63 reviews)

Who is this for?

Patients already on gluten-free diet (serology unreliable), first-degree relatives of celiac patients, equivocal serology or IgA deficiency, suspected non-coeliac gluten sensitivity

Preparation required

No fasting required. Do not change your current diet before the test — genetic results are diet-independent. Normal gluten intake is neither required nor harmful for this test.

About the clinic

Reviews, team and credentials

Independent review links and clinic-reported team information.

4.9

11,172 clinic reviews

From independent platforms

Clinical team

Unilabs CZ employs over 1,450 staff across its laboratory network, including board-certified specialists in clinical biochemistry, haematology, immunology, microbiology, pathology, and forensic genetics. All laboratory operations are supervised by qualified laboratory physicians (atestovaní lékaři) under the Czech Ministry of Health's accreditation framework. The Prague client centre at Hadovka (Praha 6 – Evropská)…

Languages: Czech

What clients say

"{"author":"Verified customer — Thyroid Panel (cz.unilabs.online)","text":"Vše proběhlo rychle a profesionálně. Výsledky jsem měla do 2 dnů a online interpretace mi vše srozumitelně vysvětlila.","rating":5}"

"{"author":"Verified customer — Women's Prevention Panel (cz.unilabs.online)","text":"Objednání přes e-shop bylo jednoduché, odběr proběhl bez čekání, výsledky přišly rychle. Rozhodně doporučuji.","rating":5}"

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