Lipolytic Serum Injections (Fat Dissolving)

Lipolytic serum injections at Top Laser Olomouc offer a chemical approach to reducing localised fat deposits — complementary to the clinic's Accent XL radiofrequency contouring system and suited to patients targeting smaller, more defined areas such as the submental zone (double chin). The procedure involves injecting a phosphatidylcholine or deoxycholate-based lipolytic compound directly into the subcutaneous fat layer, where it disrupts adipocyte membranes, triggering controlled fat cell death and gradual volume reduction over the weeks following treatment. The released lipids are cleared by the lymphatic system. At Top Laser, the treatment is offered for the submental area (1 700 Kč), abdomen, and back. Dr. Nyklová Skřivánková's medical background ensures precise injection depth and distribution pattern to achieve uniform fat reduction without damaging surrounding tissue.

Injectable lipolysis is a well-established body contouring method in European aesthetic medicine, particularly for areas too small or anatomically complex for radiofrequency or surgical approaches. The active compounds used in lipolytic serums work through cell membrane disruption: phosphatidylcholine (PPC) is a naturally occurring phospholipid that integrates into the adipocyte membrane and increases its permeability, causing the cell to release its triglyceride contents; deoxycholate (DC) is a bile acid that acts as a solubilising detergent, disrupting the lipid bilayer. The resulting adipocyte lysis triggers a local inflammatory response over the following days — reflected as swelling, tenderness, and warmth in the treated area — which resolves as macrophages clear the cellular debris and the lymphatic system transports released fatty acids to the liver for metabolism. At Top Laser Olomouc, the primary indication is the submental area — double chin reduction — where the compact anatomy allows precise serum delivery with a short series of treatments. Abdominal and back fat reduction are also offered for larger deposits. A typical session begins with skin cleansing and grid marking to guide even injection distribution. Multiple fine-needle injections are made at 1 cm intervals throughout the target zone, with the total serum volume and concentration determined by the area size and fat layer depth assessed at consultation. Post-treatment swelling is most pronounced in the first 48–72 hours; patients are advised to wear chin compression garments for submental treatments and avoid strenuous activity for 48 hours. Most patients experience two to four sessions spaced four to six weeks apart for meaningful fat reduction; results are maintained long-term as destroyed adipocytes do not regenerate. The procedure differs from the clinic's Accent XL radiofrequency service: ACCENT addresses larger areas with heat-mediated fat disruption and simultaneous skin tightening, while lipolytic injections are better suited for focal, well-defined deposits where injector precision provides an advantage. The two approaches can be combined in a complementary protocol. Contraindications include active infection at the injection site, pregnancy and breastfeeding, liver disease, and lipid metabolism disorders.