High-Dose Vitamin C IV (25g)

Mega-dose intravenous vitamin C infusion delivering 25 grams of ascorbic acid directly into the bloodstream. At this concentration, plasma vitamin C levels reach pharmacological ranges far beyond what oral supplementation can achieve, activating antioxidant and pro-oxidant pathways that are the subject of ongoing clinical research.

High-dose intravenous vitamin C (IVC) therapy at 25 grams represents a pharmacological dose — approximately 250 to 500 times the recommended daily oral intake — that produces plasma concentrations unattainable through dietary or supplemental routes. At these levels, vitamin C behaves differently than at nutritional doses, generating hydrogen peroxide in extracellular fluid through a pro-oxidant mechanism that has been studied extensively in oncology research settings. The 45-minute infusion at TGWAC is administered under medical supervision with pre-treatment screening. Patients receiving high-dose vitamin C for the first time are typically assessed for G6PD (glucose-6-phosphate dehydrogenase) deficiency, a genetic condition that can cause haemolytic anaemia when exposed to high ascorbic acid levels. The clinic may also check kidney function, as large doses of vitamin C are metabolised to oxalate and excreted renally. Beyond the research context, high-dose IVC is widely used in integrative medicine for immune support, particularly during periods of acute illness or recovery. Vitamin C is a cofactor for multiple enzymatic reactions including collagen synthesis, carnitine production, and the hydroxylation of neurotransmitters. It also regenerates other antioxidants, notably vitamin E, and supports the function of neutrophils, lymphocytes, and natural killer cells. Patients receiving the 25g infusion typically remain well-hydrated before and after treatment. Some individuals report mild transient thirst or a warm sensation during the drip, which is normal. The clinic recommends spacing high-dose vitamin C sessions at least one week apart for wellness purposes, though frequency may be adjusted based on clinical context and physician guidance. TGWAC physicians can incorporate IVC into a broader longevity protocol alongside NMN, glutathione, and biomarker monitoring.