Type
Regenerative Therapy
Duration
25 min
What's included
4 deliverables in this treatment
- Consultation and zone assessment
- Topical numbing cream
- Polynucleotide (salmon DNA) micro-injection session
- Course plan — face and eye protocols include 2 treatments
Polynucleotide therapy — popularly known as 'salmon DNA' — is one of the newest regenerative injectables in aesthetic medicine, and TobePrime Clinic offers it for the full face, the delicate eye area, and scar regeneration. Purified polynucleotide fragments derived from salmon DNA may support tissue repair, hydration, and elasticity by creating a regenerative environment in the dermis, rather than filling or freezing it. Courses of two sessions are the standard protocol for face and eye treatments.
About this treatment
Polynucleotides (PN/PDRN) are chains of purified DNA fragments, typically sourced from salmon, with high biocompatibility in human tissue. Injected into the dermis, they are associated with improved fibroblast activity, tissue oxygenation, hydration, and elasticity — a regenerative rather than volumising mechanism. This has made 'salmon DNA' one of the fastest-growing categories in European aesthetic medicine, particularly for zones where conventional…
TobePrime Clinic offers three published protocols. Full-face regeneration (14,000 Kč for 2 treatments) delivers intensive regeneration across the whole face — improving skin density, fine lines, and overall quality. Eye-area treatment (10,000 Kč for 2 treatments) targets the thinnest, most delicate skin on the face, where polynucleotides can brighten, firm, and smooth crepiness with a low risk profile. Scar therapy (5,000 Kč per session) uses the…
Sessions take 20–25 minutes and involve a series of micro-injections after topical numbing. Mild swelling or papules settle within 24–48 hours. Face and eye protocols are delivered as two sessions spaced several weeks apart, with skin quality improving progressively over the following 1–3 months. Results are commonly maintained with a top-up session every 6–9 months.
Good to know
- Mechanism
- Regenerative polynucleotides (PDRN) — not a filler
- Protocol
- 2 sessions for face/eye area; per-session for scars
- Best-known use
- Under-eye and delicate-skin rejuvenation
- Downtime
- 24–48 h mild swelling/papules
Who is this for?
Under-eye crepiness and dark circles, thin or tired skin, scar regeneration, clients preferring regenerative over volumising treatments
About the clinic
Reviews, team and credentials
Independent review links and clinic-reported team information.
Clinical team
Physician-led aesthetic team including MUDr. Alica Paveleková (aesthetic physician with many years of experience, specialising in botulinum toxin, fillers, and the clinic's signature Prime Lips technique) and MUDr. Anna Hrazdírová. All injectable and laser procedures are performed by medical doctors.
Languages: Czech
Treatment highlights
- Consultation and zone assessment
- Topical numbing cream
+2 more items in What's included
Full face: 14,000 Kč for a course of 2 treatments. Eye area: 10,000 Kč for 2 treatments. Scar therapy (healing and tissue regeneration): 5,000 Kč per session. Sessions take 20–25 minutes.