Type
Blood Testing
Biomarkers
11
Duration
10 min
Results
48 hours
Serum 25-hydroxyvitamin D measurement assessing total vitamin D status from dietary intake and sun exposure. At 470 CZK (~19 EUR), this is the standard screening test for vitamin D deficiency — essential at Central European latitudes where UV-B exposure is insufficient for cutaneous synthesis for half the year.
25-hydroxyvitamin D (calcidiol) is the accepted clinical standard for evaluating vitamin D status. It reflects the combined contribution of dietary intake, supplementation, and cutaneous synthesis from ultraviolet-B radiation. The test measures total 25(OH)D, encompassing both D2 (ergocalciferol, plant-derived) and D3 (cholecalciferol, from animal sources and sunlight). Deficiency is defined as serum levels below 50 nmol/L (20 ng/mL), insufficiency as 50-75 nmol/L, and optimal status as 75-125 nmol/L. At Prague's latitude (50.1°N), effective cutaneous vitamin D synthesis occurs only from approximately late March through September. During the remaining months, supplementation is necessary for most individuals. Vitamin D receptors are present in virtually every human tissue. Beyond the well-characterised role in calcium absorption and bone mineralisation, adequate vitamin D status is associated with immune regulation, muscle strength, cardiovascular health, and mood regulation. Chronic deficiency triggers secondary hyperparathyroidism, which mobilises calcium from bone and accelerates osteoporotic bone loss. Population studies consistently show that 60-80% of Central European adults are vitamin D deficient during winter months. Testing in late winter (February-March) captures the nadir of annual vitamin D status and is the most clinically informative timing. The Czech Republic's historical iodine deficiency programmes have improved awareness of micronutrient testing, but vitamin D screening remains underutilised in routine clinical practice. Self-pay testing through SYNLAB makes it accessible without waiting for a physician referral. At 470 CZK (~19 EUR), this test is moderately priced compared to the 20-50 EUR range at German labs. Blood draw and serum separation are included. Results within two business days.
Key Details
- Biomarker
- Vitamin D 25-OH
- Results
- 2 days
- Price
- 470 CZK (~€19)
Who Is This For?
Seasonal screening, bone health, fatigue investigation, supplement dosing
What's Included
Preparation Required
No fasting required. No need to stop vitamin D supplements before testing.
Panel Categories
Biomarkers Tested
11A trace mineral essential for iron metabolism, connective tissue formation, and antioxidant defense. The copper/zinc ratio is an emerging marker of inflammation and oxidative stress. Both deficiency and excess can cause problems.
Essential for DNA synthesis, cell division, and red blood cell formation. Folate deficiency causes megaloblastic anemia and, during pregnancy, increases the risk of neural tube defects. Works closely with vitamin B12.
Involved in over 300 enzymatic reactions including energy production, muscle function, and nerve signaling. Magnesium deficiency is common and associated with muscle cramps, anxiety, insomnia, and increased cardiovascular risk.
A trace mineral crucial for thyroid hormone metabolism, antioxidant defense (via selenoproteins), and immune function. Selenium deficiency can impair thyroid function and increase susceptibility to viral infections.
A fat-soluble vitamin essential for vision, immune function, skin health, and cell growth. Both deficiency and excess can cause health problems. Levels are tightly regulated by the liver.
Essential for nerve function, DNA synthesis, and red blood cell formation. B12 deficiency can cause anemia, neuropathy, fatigue, and cognitive impairment. Common in vegans, vegetarians, older adults, and those taking metformin or acid-reducing medications.
A powerful water-soluble antioxidant essential for collagen synthesis, immune function, and iron absorption. Vitamin C deficiency causes scurvy. It also supports wound healing and protects against oxidative stress.
The best indicator of overall vitamin D status. Vitamin D is essential for calcium absorption, bone health, immune function, and mood regulation. Deficiency is extremely common, especially in northern latitudes, and linked to increased disease risk.
A fat-soluble antioxidant that protects cell membranes from oxidative damage. Vitamin E works synergistically with vitamin C and selenium. Deficiency is rare but can cause nerve and muscle damage.
Essential for blood clotting and bone metabolism. Vitamin K activates proteins needed for blood coagulation and calcium regulation in bones. Deficiency increases bleeding risk and may contribute to osteoporosis.
An essential trace mineral involved in immune function, wound healing, DNA synthesis, and testosterone production. Zinc deficiency impairs immune response, delays wound healing, and can cause hair loss and taste changes.
470 CZK all-inclusive (blood draw + serum separation included).
- Category
- Diagnostic
- Sample Type
- Blood (venous draw)
- Duration
- 10 min
- Results
- 48 hours