Type
Blood Testing
Biomarkers
11
Duration
10 min
Results
48 hours
Sample
Blood (venous draw)
What's included
1 deliverable in this treatment
- 25-hydroxyvitamin D (total)
Serum 25-hydroxyvitamin D measurement at SYNLAB Brno assessing total vitamin D status from dietary intake and sun exposure. At 470 CZK (~19 EUR), essential screening at Central European latitudes — Brno sits at 49.2°N where UV-B exposure is inadequate for cutaneous synthesis from October through March.
About this treatment
25-hydroxyvitamin D (calcidiol) is the accepted clinical standard for evaluating vitamin D status, reflecting the combined contribution of dietary intake, supplementation, and cutaneous synthesis from ultraviolet-B radiation. The test measures total 25(OH)D, encompassing both D2 (ergocalciferol, from plant sources) and D3 (cholecalciferol, from animal sources and sunlight).
Deficiency is defined as serum levels below 50 nmol/L (20 ng/mL), insufficiency as 50-75 nmol/L, and optimal status as 75-125 nmol/L. At Brno's latitude (49.2°N), effective cutaneous vitamin D synthesis occurs only from approximately late March through September — during the remaining months, the solar zenith angle is too low for UV-B photons to reach the skin in sufficient quantities for meaningful cholecalciferol production. Supplementation is necessary…
Vitamin D receptors are expressed in virtually every human tissue type. Beyond the classical role in intestinal calcium absorption and bone mineralisation, adequate vitamin D status is associated with immune modulation, skeletal muscle strength, cardiovascular health, and psychological wellbeing. Chronic deficiency triggers secondary hyperparathyroidism, which mobilises calcium from bone and accelerates osteoporotic bone loss — a particular concern for…
Good to know
- Biomarker
- Vitamin D 25-OH
- Results
- 2 days
- Price
- 470 CZK (~€19)
Who is this for?
Seasonal screening, bone health, fatigue investigation, supplement dosing
Preparation required
No fasting required. No need to stop vitamin D supplements before testing.
Panel categories
Biomarkers tested
11A trace mineral essential for iron metabolism, connective tissue formation, and antioxidant defense. The copper/zinc ratio is an emerging marker of inflammation and oxidative stress. Both deficiency and excess can cause problems.
Essential for DNA synthesis, cell division, and red blood cell formation. Folate deficiency causes megaloblastic anemia and, during pregnancy, increases the risk of neural tube defects. Works closely with vitamin B12.
Involved in over 300 enzymatic reactions including energy production, muscle function, and nerve signaling. Magnesium deficiency is common and associated with muscle cramps, anxiety, insomnia, and increased cardiovascular risk.
A trace mineral crucial for thyroid hormone metabolism, antioxidant defense (via selenoproteins), and immune function. Selenium deficiency can impair thyroid function and increase susceptibility to viral infections.
A fat-soluble vitamin essential for vision, immune function, skin health, and cell growth. Both deficiency and excess can cause health problems. Levels are tightly regulated by the liver.
Essential for nerve function, DNA synthesis, and red blood cell formation. B12 deficiency can cause anemia, neuropathy, fatigue, and cognitive impairment. Common in vegans, vegetarians, older adults, and those taking metformin or acid-reducing medications.
A powerful water-soluble antioxidant essential for collagen synthesis, immune function, and iron absorption. Vitamin C deficiency causes scurvy. It also supports wound healing and protects against oxidative stress.
The best indicator of overall vitamin D status. Vitamin D is essential for calcium absorption, bone health, immune function, and mood regulation. Deficiency is extremely common, especially in northern latitudes, and linked to increased disease risk.
A fat-soluble antioxidant that protects cell membranes from oxidative damage. Vitamin E works synergistically with vitamin C and selenium. Deficiency is rare but can cause nerve and muscle damage.
Essential for blood clotting and bone metabolism. Vitamin K activates proteins needed for blood coagulation and calcium regulation in bones. Deficiency increases bleeding risk and may contribute to osteoporosis.
An essential trace mineral involved in immune function, wound healing, DNA synthesis, and testosterone production. Zinc deficiency impairs immune response, delays wound healing, and can cause hair loss and taste changes.
About the clinic
Reviews, team and credentials
Independent review links and clinic-reported team information.
Clinical team
Part of Europe's largest laboratory network with 9 collection points across Brno. Walk-in blood draws available weekday mornings from 06:00 at the Titanium business complex (Building D, ground floor), wheelchair accessible, near Brno hlavní nádraží train station. Order packages online via e-shop, present yourself at any collection point, receive results in 2 business days via secure email.
Languages: czech, english
Treatment highlights
- 25-hydroxyvitamin D (total)
470 CZK all-inclusive (blood draw + serum separation included).