Profhilo Bio-Remodeling

Profhilo is a high-concentration, non-crosslinked hyaluronic acid bio-remodeler injected at specific anatomical points on the face, neck, décolletage, or hands. Unlike volumising fillers, it does not add bulk — instead it spreads across the tissue plane, stimulating fibroblasts to produce collagen and elastin and rehydrating the dermis from within. At Skinderm Ostrava, licensed dermatologists administer 2.0 ml per session using the five-point BAP (Bio Aesthetic Points) injection technique, with a second session one month later to consolidate the remodelling effect.

Profhilo contains one of the highest concentrations of hyaluronic acid available in an injectable product — 64 mg per 2 ml — yet it is non-crosslinked, meaning the HA chains remain in their natural non-modified form. When injected into the dermis and sub-dermis, it flows through the tissue rather than staying localised, creating a bio-stimulating wave that hydrates, firms, and gradually improves skin laxity over the course of weeks. The treatment protocol at Skinderm follows the standard BAP (Bio Aesthetic Points) approach: five points per side of the face, spaced to cover cheeks, cheekbones, chin, and jawline in a single session of approximately 30 minutes. Practitioners use fine needles or cannulas depending on the area and individual anatomy. A second identical session is scheduled four weeks later; together the two sessions form the foundational course. Some patients elect a single annual maintenance session thereafter. Profhilo Structura, priced at 7,000 Kč per session, is a denser formulation designed for areas requiring more structural support — particularly under-chin, inner arms, and above the knee — where tissue laxity is more marked. Results build progressively rather than appearing immediately. Mild swelling and injection-site marks resolve within hours to a day. Firming and glow improvements are noticeable at 4–6 weeks post-first-session; continued collagen synthesis means the result continues to improve for up to 3 months after the second session and may last 6–12 months. Profhilo is suitable for all skin types and particularly well-suited to patients in their 30s–60s seeking natural rejuvenation without the volumising effect of traditional fillers. It can be combined with botulinum toxin, laser, and other procedures. Contraindications include pregnancy, nursing, autoimmune conditions, and active skin infections. Patients are advised to avoid aspirin and blood-thinning supplements in the week before each session.